ENSP00000338272 (Macaca fascicularis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 ENSP00000338272 T047243_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
HEY1
M02793_2.00
Homo sapiens
SVCACGTGYC

GRCACGTGBS
SELEX
Jolma et al.(2013)
HEY1_1
0.914 1.000
HEY1
M04152_2.00
Homo sapiens
NRCACGTGVV

BBCACGTGYN
SELEX
Yin et al.(2017)
HEY1_eDBD_HT-SELEX
0.914 1.000
HEY1
M04154_2.00
Homo sapiens
NRCRCGYGVV

BBCRCGYGYN
SELEX
Yin et al.(2017)
HEY1_FL_HT-SELEX
0.914 1.000
HEY1
M04153_2.00
Homo sapiens
NRCRCGYGVV

BBCRCGYGYN
SELEX
Yin et al.(2017)
HEY1_eDBD_Methyl-HT-SELEX
0.914 1.000
HEY1
M04155_2.00
Homo sapiens
NDCRCGYRSN

NSYRCGYGHN
SELEX
Yin et al.(2017)
HEY1_FL_Methyl-HT-SELEX
0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000338272 bHLH 50 109

Links

Other bHLH family TFs
Other Macaca fascicularis TFs

84 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
HEY1 Callithrix jacchus ENSCJAG00000000477 I 0.914
HEY1 Gorilla gorilla ENSGGOG00000009960 I 0.914
HEY1 Homo sapiens ENSG00000164683 D 0.914
HEY1 Macaca mulatta ENSMMUG00000002740 I 0.914
HEY1 Pan troglodytes ENSPTRG00000020364 I 0.914
HEY1 Ochotona princeps ENSOPRG00000003055 I 0.889
HEY1 Procavia capensis ENSPCAG00000000598 I 0.889
ENSAMEG00000017517 Ailuropoda melanoleuca ENSAMEG00000017517 I 0.889
ENSP00000338272-D1 Bos grunniens ENSP00000338272-D1 I 0.889
HEY1 Tupaia belangeri ENSTBEG00000010367 I 0.889
HEY1 Microcebus murinus ENSMICG00000001913 I 0.889
HEY1 Oryctolagus cuniculus ENSOCUG00000016568 I 0.889
ENSPPYG00000018693 Pongo abelii ENSPPYG00000018693 I 0.871
ENSPFOG00000001913 Poecilia formosa ENSPFOG00000001913 I 0.871
ENSONIG00000003087 Oreochromis niloticus ENSONIG00000003087 I 0.871
ENSNLEG00000002239 Nomascus leucogenys ENSNLEG00000002239 I 0.871
Hey1 Mus musculus ENSMUSG00000040289 I 0.871
ENSOARG00000008063 Ovis aries ENSOARG00000008063 I 0.871
ENSPSIG00000003791 Pelodiscus sinensis ENSPSIG00000003791 I 0.871
HEY1 Oryzias latipes ENSORLG00000008268 I 0.871
ENSPANG00000018687 Papio anubis ENSPANG00000018687 I 0.871
ENSSHAG00000017958 Sarcophilus harrisii ENSSHAG00000017958 I 0.871
Myotis_brandtii_HEY1_10021379 Myotis brandtii Myotis_brandtii_HEY1_10021379 I 0.871
Gfo_R007552 Geospiza fortis Gfo_R007552 I 0.871
Ogr14041 Ophisaurus gracilis Ogr14041 I 0.871
Pvit_00065 Pogona vitticeps Pvit_00065 I 0.871
hey1.S Xenopus laevis XB-GENE-865637 I 0.871
hey1 Xenopus tropicalis XB-GENE-486694 I 0.871
Brh_R005579 Buceros rhinoceros Brh_R005579 I 0.871
Afo_R005157 Aptenodytes forsteri Afo_R005157 I 0.871
HEY1 Sus scrofa ENSSSCG00000006159 I 0.871
ENSMPUG00000001859 Mustela putorius furo ENSMPUG00000001859 I 0.871
ENSSTOG00000023191 Ictidomys tridecemlineatus ENSSTOG00000023191 I 0.871
HEY1 Tetraodon nigroviridis ENSTNIG00000018401 I 0.871
HEY1 Takifugu rubripes ENSTRUG00000013573 I 0.871
Hey1 Rattus norvegicus ENSRNOG00000011593 I 0.871
HEY1 Otolemur garnettii ENSOGAG00000007210 I 0.871
ENSGMOG00000013488 Gadus morhua ENSGMOG00000013488 I 0.871
ENSGMOG00000017811 Gadus morhua ENSGMOG00000017811 I 0.871
HEY1 Monodelphis domestica ENSMODG00000006648 I 0.871
HEY1 Equus caballus ENSECAG00000017010 I 0.871
ENSFALG00000008605 Ficedula albicollis ENSFALG00000008605 I 0.871
HEY1 Felis catus ENSFCAG00000025542 I 0.871
HEY1 Gasterosteus aculeatus ENSGACG00000008712 I 0.871
HEY1 Dasypus novemcinctus ENSDNOG00000031981 I 0.871
ENSLACG00000015540 Latimeria chalumnae ENSLACG00000015540 I 0.871
HEY1 Cavia porcellus ENSCPOG00000008527 I 0.871
HEY1 Canis familiaris ENSCAFG00000008391 I 0.871
ENSCSAG00000013410 Chlorocebus sabaeus ENSCSAG00000013410 I 0.871
hey1 Gasterosteus aculeatus ENSGACG00000003436 I 0.871
HEY1 Loxodonta africana ENSLAFG00000011488 I 0.871
hey1 Danio rerio ENSDARG00000070538 I 0.871
HEY1 Bos taurus ENSBTAG00000015717 I 0.871
hey1 Takifugu rubripes ENSTRUG00000014561 I 0.868
hey1 Tetraodon nigroviridis ENSTNIG00000017785 I 0.868
heyl Gasterosteus aculeatus ENSGACG00000007492 I 0.851
LotgiG171867 Lottia gigantea LotgiG171867 I 0.851
ENSXMAG00000006950 Xiphophorus maculatus ENSXMAG00000006950 I 0.851
TC001593 Tribolium castaneum TC001593 I 0.851
YQE_09192 Dendroctonus ponderosae YQE_09192 I 0.851
ENSAMXG00000011237 Astyanax mexicanus ENSAMXG00000011237 I 0.851
LDEC001043 Leptinotarsa decemlineata LDEC001043 I 0.851
heyl Danio rerio ENSDARG00000055798 I 0.851
ENSLOCG00000001853 Lepisosteus oculatus ENSLOCG00000001853 I 0.851
ENSXMAG00000014241 Xiphophorus maculatus ENSXMAG00000014241 I 0.851
ENSONIG00000004726 Oreochromis niloticus ENSONIG00000004726 I 0.851
ENSPFOG00000015536 Poecilia formosa ENSPFOG00000015536 I 0.851
ENSGMOG00000011084 Gadus morhua ENSGMOG00000011084 I 0.851
HEYL Felis catus ENSFCAG00000010963 I 0.851
CapteG228069 Capitella teleta CapteG228069 I 0.851
heyl Tetraodon nigroviridis ENSTNIG00000009228 I 0.851
heyl Oryzias latipes ENSORLG00000013651 I 0.851
heyl Takifugu rubripes ENSTRUG00000003399 I 0.851
ENSMEUG00000009781 Macropus eugenii ENSMEUG00000009781 I 0.846
HEY1 Anolis carolinensis ENSACAG00000013410 I 0.846
ENSLOCG00000004692 Lepisosteus oculatus ENSLOCG00000004692 I 0.846
CGI_10018323 Crassostrea gigas CGI_10018323 I 0.841
Ocbimv22039104m.g Octopus bimaculoides Ocbimv22039104m.g I 0.841
Sakowv30023592m.g Saccoglossus kowalevskii Sakowv30023592m.g I 0.841
SPU_009465 Strongylocentrotus purpuratus SPU_009465 I 0.841
ENSLACG00000012215 Latimeria chalumnae ENSLACG00000012215 I 0.841
ISCW011251 Ixodes scapularis ISCW011251 I 0.841
Aqu1.218726 Amphimedon queenslandica Aqu1.218726 I 0.838
HEY1 Meleagris gallopavo ENSMGAG00000011620 I 0.272