CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ENSP00000338272
(
Macaca fascicularis
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
PF00010 (HLH)
IPR001092
ENSP00000338272
T047243_2.00
GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
HEY1
M02793_2.00
Homo sapiens
SVCACGTGYC
GRCACGTGBS
SELEX
Jolma et al.(2013)
HEY1_1
0.914
1.000
HEY1
M04152_2.00
Homo sapiens
NRCACGTGVV
BBCACGTGYN
SELEX
Yin et al.(2017)
HEY1_eDBD_HT-SELEX
0.914
1.000
HEY1
M04154_2.00
Homo sapiens
NRCRCGYGVV
BBCRCGYGYN
SELEX
Yin et al.(2017)
HEY1_FL_HT-SELEX
0.914
1.000
HEY1
M04153_2.00
Homo sapiens
NRCRCGYGVV
BBCRCGYGYN
SELEX
Yin et al.(2017)
HEY1_eDBD_Methyl-HT-SELEX
0.914
1.000
HEY1
M04155_2.00
Homo sapiens
NDCRCGYRSN
NSYRCGYGHN
SELEX
Yin et al.(2017)
HEY1_FL_Methyl-HT-SELEX
0.914
1.000
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000338272
bHLH
50
109
RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLH
Links
Other
bHLH
family TFs
Other
Macaca fascicularis
TFs
84 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy