|
HHAL000695-PA
(Halyomorpha halys)
bHLH
|
TF Information |
Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
PF00010 (HLH) |
IPR001092 |
HHAL000695-PA |
T051396_2.00 |
Misc (2018-Jan-19) |
NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
No direct experiments |
|
|
|
|
|
Motifs from related TFs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
Tcf21
M01746_2.00 |
Mus musculus |
RMCAKMTGK |
MCAKMTGKY |
PBM
Weirauch et al.(2014)
pTH5087
|
0.883
|
0.942
|
Tcf21
M02819_2.00 |
Mus musculus |
VNAACAGCTGTTVN |
NBAACAGCTGTTNB |
SELEX
Jolma et al.(2013)
Tcf21_1
|
0.883
|
0.942
|
TCF21
M04092_2.00 |
Homo sapiens |
BAACAGCTGBYN |
NRVCAGCTGTTV |
SELEX
Yin et al.(2017)
TCF21_eDBD_HT-SELEX_1
|
0.883
|
0.942
|
TCF21
M04093_2.00 |
Homo sapiens |
NRCCATATGKYV |
BRMCATATGGYN |
SELEX
Yin et al.(2017)
TCF21_eDBD_HT-SELEX_2
|
0.883
|
0.942
|
TCF21
M04094_2.00 |
Homo sapiens |
BAACAGCTGTYV |
BRACAGCTGTTV |
SELEX
Yin et al.(2017)
TCF21_eDBD_Methyl-HT-SELEX_1
|
0.883
|
0.942
|
TCF21
M04095_2.00 |
Homo sapiens |
BACCATATGKYV |
BRMCATATGGTV |
SELEX
Yin et al.(2017)
TCF21_eDBD_Methyl-HT-SELEX_2
|
0.883
|
0.942
|
Msc
M01730_2.00 |
Mus musculus |
NVCRKMYGBN |
NVCRKMYGBN |
PBM
Weirauch et al.(2014)
pTH5112
|
0.883
|
0.923
|
MSC
M02801_2.00 |
Homo sapiens |
AACAGCTGTT |
AACAGCTGTT |
SELEX
Jolma et al.(2013)
MSC_1
|
0.883
|
0.923
|
MSC
M04183_2.00 |
Homo sapiens |
NRMCAGMTGBYN |
NRVCAKCTGKYN |
SELEX
Yin et al.(2017)
MSC_eDBD_HT-SELEX_1
|
0.883
|
0.923
|
MSC
M04184_2.00 |
Homo sapiens |
NRVCAYVTGBYN |
NRVCABRTGBYN |
SELEX
Yin et al.(2017)
MSC_eDBD_HT-SELEX_2
|
0.883
|
0.923
|
MSC
M04187_2.00 |
Homo sapiens |
NRMCAGCTGBYV |
BRVCAGCTGKYN |
SELEX
Yin et al.(2017)
MSC_FL_HT-SELEX_1
|
0.883
|
0.923
|
MSC
M04188_2.00 |
Homo sapiens |
BRMCATATGKYN |
NRMCATATGKYV |
SELEX
Yin et al.(2017)
MSC_FL_HT-SELEX_2
|
0.883
|
0.923
|
MSC
M04185_2.00 |
Homo sapiens |
NRVCAGCTGBBN |
NVVCAGCTGBYN |
SELEX
Yin et al.(2017)
MSC_eDBD_Methyl-HT-SELEX_1
|
0.883
|
0.923
|
MSC
M04186_2.00 |
Homo sapiens |
BRMCATATGKYV |
BRMCATATGKYV |
SELEX
Yin et al.(2017)
MSC_eDBD_Methyl-HT-SELEX_2
|
0.883
|
0.923
|
MSC
M04189_2.00 |
Homo sapiens |
BRACAGCTGTYV |
BRACAGCTGTYV |
SELEX
Yin et al.(2017)
MSC_FL_Methyl-HT-SELEX_1
|
0.883
|
0.923
|
MSC
M04190_2.00 |
Homo sapiens |
BRMCATATGKYV |
BRMCATATGKYV |
SELEX
Yin et al.(2017)
MSC_FL_Methyl-HT-SELEX_2
|
0.883
|
0.923
|
For this family, TFs with SR scores > 0.838 will likely have a similar motif |