TF Information

HHAL008564-PA *(Halyomorpha halys)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00010 (HLH)	IPR001092	HHAL008564-PA	T051420_2.00	Misc (2018-Jan-19)
NCBI Gene Info: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
tgo M06005_2.00	Drosophila melanogaster	RDDTCGTGAYY	RRTCACGAHHY	B1H Zhu et al.(2011) dys_tgo_SANGER_5_FBgn0015014	0.914	1.000
tgo M06006_2.00	Drosophila melanogaster	SDTTGCGTGAC	GTCACGCAAHS	B1H Zhu et al.(2011) ss_tgo_SANGER_10_FBgn0015014	0.914	1.000
tgo M06007_2.00	Drosophila melanogaster	KCACGTGAC	GTCACGTGM	B1H Zhu et al.(2011) tgo_cyc_SANGER_5_FBgn0015014	0.914	1.000
tgo M06008_2.00	Drosophila melanogaster	RTACGTGAC	GTCACGTAY	B1H Zhu et al.(2011) tgo_sima_SANGER_5_FBgn0015014	0.914	1.000
tgo M06009_2.00	Drosophila melanogaster	VWACGTGACY	RGTCACGTWB	B1H Zhu et al.(2011) tgo_sim_SANGER_5_FBgn0015014	0.914	1.000
tgo M06010_2.00	Drosophila melanogaster	TGCGTGAC	GTCACGCA	B1H Zhu et al.(2011) tgo_ss_SANGER_5_FBgn0015014	0.914	1.000
tgo M06011_2.00	Drosophila melanogaster	RCACGTGAC	GTCACGTGY	B1H Zhu et al.(2011) tgo_tai_SANGER_5_FBgn0015014	0.914	1.000
tgo M06012_2.00	Drosophila melanogaster	VTACGTGACB	VGTCACGTAB	B1H Zhu et al.(2011) tgo_trh_SANGER_5_FBgn0015014	0.914	1.000
Arnt M01719_2.00	Mus musculus	NNKCACGTGMNN	NNKCACGTGMNN	PBM Weirauch et al.(2014) pTH5111	0.914	0.926
ARNT M08732_2.00	Homo sapiens	NKRCGTGMN	NKCACGYMN	Misc Kulakovskiy et al.(2013) ARNT_HUMAN.H11MO.0.B	0.914	0.926
ARNT M09459_2.00	Homo sapiens	KCACGTNN	NNACGTGM	Misc Heinz et al.(2010) T47D-HIF1b_GSE59937	0.914	0.926
ARNT M09863_2.00	Homo sapiens	NVNNNCACGTGNHHHN	NDDDNCACGTGNNNBN	Transfac Matys et al.(2006) V$ARNT_01	0.914	0.926
ARNT M09864_2.00	Homo sapiens	VVNNNRKCACGTGMYNNNBB	VVNNNRKCACGTGMYNNNBB	Transfac Matys et al.(2006) V$ARNT_02	0.914	0.926
ARNT M09865_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ARNT_Q6_01	0.914	0.926
ARNT M09866_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ARNT_Q6	0.914	0.926
Arnt2 M01720_2.00	Mus musculus	NCAYRTGMNN	NNKCAYRTGN	PBM Weirauch et al.(2014) pTH5159	0.862	0.907
ARNT2 M04170_2.00	Homo sapiens	RDCACGTGMN	NKCACGTGHY	SELEX Yin et al.(2017) ARNT2_eDBD_HT-SELEX	0.862	0.907
Arnt2 M09888_2.00	Rattus norvegicus	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ARNT2_01	0.862	0.907
For this family, TFs with SR scores > 0.838* will likely have a similar motif*