HHAL010192-PA (Halyomorpha halys)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 HHAL010192-PA T051424_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
MAX
M00938_2.00
Homo sapiens
CCACGTGH

DCACGTGG
PBM
Guo et al.(2014)
Max_L
0.869 0.846
Max
M00121_2.00
Mus musculus
NCRCRTGNN

NNCAYGYGN
PBM
Badis et al.(2009)
Max_3863
0.869 0.846
Max
M00122_2.00
Mus musculus
NNCRCRTGN

NCAYGYGNN
PBM
Badis et al.(2009)
Max_3864
0.869 0.846
Max
M01753_2.00
Mus musculus
NCAYGYKNN

NNMRCRTGN
PBM
Weirauch et al.(2014)
pTH4381
0.869 0.846
Max
M08778_2.00
Mus musculus
VVVCACGYGSN

NSCRCGTGBBB
Misc
Kulakovskiy et al.(2013)
MAX_MOUSE.H11MO.0.A
0.869 0.846
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL010192-PA bHLH 11 63

Links

Other bHLH family TFs
Other Halyomorpha halys TFs

Invalid Input OrderBy

101 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action