nhlh1 (Xenopus tropicalis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 XB-GENE-989790 T051943_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
NHLH1
M02796_2.00
Homo sapiens
CGCAGCTGCB

VGCAGCTGCG
SELEX
Jolma et al.(2013)
NHLH1_1
0.914 1.000
NHLH1
M02797_2.00
Homo sapiens
VGCAGCTGCK

MGCAGCTGCB
SELEX
Jolma et al.(2013)
NHLH1_2
0.914 1.000
NHLH1
M04162_2.00
Homo sapiens
NDGNMKCAGCTGCGYCMH

DKGRCGCAGCTGMKNCHN
SELEX
Yin et al.(2017)
NHLH1_eDBD_HT-SELEX
0.914 1.000
NHLH1
M04164_2.00
Homo sapiens
NDGNMKCAGCTGCGYCMH

DKGRCGCAGCTGMKNCHN
SELEX
Yin et al.(2017)
NHLH1_FL_HT-SELEX
0.914 1.000
Nhlh1
M08773_2.00
Mus musculus
BKGGNMNCAGCTGCGBCCYY

RRGGVCGCAGCTGNKNCCMV
Misc
Kulakovskiy et al.(2013)
HEN1_MOUSE.H11MO.0.C
0.914 1.000
NHLH1
M09875_2.00
Homo sapiens
NNDGGNMVCAGCTGVGNCCNNN

NNNGGNCBCAGCTGBKNCCHNN
Transfac
Matys et al.(2006)
V$HEN1_01
0.914 1.000
NHLH1
M09876_2.00
Homo sapiens
NDRGGVMGCAGCTGMKNCCHHN

NDDGGNMKCAGCTGCKBCCYHN
Transfac
Matys et al.(2006)
V$HEN1_02
0.914 1.000
NHLH1
M04163_2.00
Homo sapiens
NRGBMKCAGCTGCGYCCH

DGGRCGCAGCTGMKVCYN
SELEX
Yin et al.(2017)
NHLH1_eDBD_Methyl-HT-SELEX
0.914 1.000
NHLH1
M04165_2.00
Homo sapiens
DGGNMBCAGCTGCGYCCH

DGGRCGCAGCTGVKNCCH
SELEX
Yin et al.(2017)
NHLH1_FL_Methyl-HT-SELEX
0.914 1.000
Nhlh2
M00756_2.00
Mus musculus
NKCAGCTGHN

NDCAGCTGMN
PBM
Weirauch et al.(2013)
pTH3037
0.914 0.981
NHLH2
M04177_2.00
Homo sapiens
DDGNMGCAGCTGCGYCMH

DKGRCGCAGCTGCKNCHH
SELEX
Yin et al.(2017)
NHLH2_FL_HT-SELEX
0.914 0.981
NHLH2
M09878_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HEN2_Q2
0.914 0.981
NHLH2
M04178_2.00
Homo sapiens
DGGNMBCAGCTGCGYCCH

DGGRCGCAGCTGVKNCCH
SELEX
Yin et al.(2017)
NHLH2_FL_Methyl-HT-SELEX
0.914 0.981
HLH4C
M03609_2.00
Drosophila melanogaster
DDNCRCAGCTGYGNHH

DDNCRCAGCTGYGNHH
SELEX
Nitta et al.(2015)
HLH4C_1
0.891 0.923
HLH4C
M03610_2.00
Drosophila melanogaster
DRSMYCAGCTGVKSYH

DRSMBCAGCTGRKSYH
SELEX
Nitta et al.(2015)
HLH4C_2
0.891 0.923
HLH4C
M03611_2.00
Drosophila melanogaster
NRBMYCAGCTGYGNHH

DDNCRCAGCTGRKVYN
SELEX
Nitta et al.(2015)
HLH4C_3
0.891 0.923
HLH4C
M05963_2.00
Drosophila melanogaster
CACCTGMDCC

GGHKCAGGTG
B1H
Zhu et al.(2011)
HLH4C_da_SANGER_5_3_FBgn0011277
0.891 0.923
HLH4C
M05964_2.00
Drosophila melanogaster
MCAYCTGMGMMM

KKKCKCAGRTGK
B1H
Zhu et al.(2011)
HLH4C_da_SANGER_5_4_FBgn0011277
0.891 0.923
HLH4C
M05965_2.00
Drosophila melanogaster
VNHHVCACCTGMBNC

GNVKCAGGTGBDDNB
B1H
Zhu et al.(2011)
HLH4C_da_SANGER_5_FBgn0011277
0.891 0.923
HLH4C
M05966_2.00
Drosophila melanogaster
RGSMYCAGCTGCGYY

RRCGCAGCTGRKSCY
B1H
Zhu et al.(2011)
HLH4C_SANGER_5_FBgn0011277
0.891 0.923
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
XP_002937307 bHLH 71 123

Links

Other bHLH family TFs
Other Xenopus tropicalis TFs

170 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Nhlh1 Mus musculus ENSMUSG00000051251 D 0.914
NHLH2 Homo sapiens ENSG00000177551 D 0.914
HLH4C Drosophila melanogaster FBgn0011277 D 0.891
NHLH1 Homo sapiens ENSG00000171786 D 0.914
Nhlh2 Mus musculus ENSMUSG00000048540 D 0.914
TC007725 Tribolium castaneum TC007725 I 0.894
SPU_009231 Strongylocentrotus purpuratus SPU_009231 I 0.894
SMAR007908 Strigamia maritima SMAR007908 I 0.894
RPRC001173 Rhodnius prolixus RPRC001173 I 0.894
PHUM229200 Pediculus humanus PHUM229200 I 0.894
NV10733 Nasonia vitripennis NV10733 I 0.914
YQE_00442 Dendroctonus ponderosae YQE_00442 I 0.894
Cmyd_10010324 Chelonia mydas Cmyd_10010324 I 0.894
Cmyd_10001044 Chelonia mydas Cmyd_10001044 I 0.882
Cflo_11933--XP_001122281.1_APIME Camponotus floridanus Cflo_11933--XP_001122281.1_APIME I 0.914
Brh_R005283 Buceros rhinoceros Brh_R005283 I 0.861
Alligator_sinensis_CCG018876.1 Alligator sinensis Alligator_sinensis_CCG018876.1 I 0.894
Alligator_sinensis_CCG011163.1 Alligator sinensis Alligator_sinensis_CCG011163.1 I 0.914
Aan_R014318 Calypte anna Aan_R014318 I 0.894
HHAL001761-PA Halyomorpha halys HHAL001761-PA I 0.894
YQE_11502 Dendroctonus ponderosae YQE_11502 I 0.894
YQE_04623 Dendroctonus ponderosae YQE_04623 I 0.894
MESCA010279 Megaselia scalaris MESCA010279 I 0.867
MCINX015834 Melitaea cinxia MCINX015834 I 0.894
GJ15714 Drosophila virilis FBgn0202902 I 0.891
GD16284 Drosophila simulans FBgn0187911 I 0.891
GM12676 Drosophila sechellia FBgn0167612 I 0.891
GL14555 Drosophila persimilis FBgn0152160 I 0.891
GI16068 Drosophila mojavensis FBgn0138817 I 0.891
GH17630 Drosophila grimshawi FBgn0125100 I 0.891
GG18528 Drosophila erecta FBgn0110741 I 0.891
GF20856 Drosophila ananassae FBgn0097862 I 0.891
GA15893 Drosophila pseudoobscura FBgn0075909 I 0.891
GK16457 Drosophila willistoni FBgn0218459 I 0.891
GE16844 Drosophila yakuba FBgn0234336 I 0.891
LotgiG133561 Lottia gigantea LotgiG133561 I 0.894
KGM_06532 Danaus plexippus KGM_06532 I 0.894
ISCW014797 Ixodes scapularis ISCW014797 I 0.894
HMEL010237 Heliconius melpomene HMEL010237 I 0.838
HelroG94416 Helobdella robusta HelroG94416 I 0.870
HelroG153470 Helobdella robusta HelroG153470 I 0.870
HelroG138545 Helobdella robusta HelroG138545 I 0.914
GB53325 Apis mellifera GB53325 I 0.914
GB49291 Apis mellifera GB49291 I 0.914
L798_00559 Zootermopsis nevadensis L798_00559 I 0.894
nRc.2.0.1.g35713 Romanomermis culicivorax nRc.2.0.1.g35713 I 0.870
AMIN011405 Anopheles minimus AMIN011405 I 0.894
AMEM004741 Anopheles merus AMEM004741 I 0.894
AMEC009920 Anopheles melas AMEC009920 I 0.894
AMAM022568 Anopheles maculatus AMAM022568 I 0.894
AFUN005050 Anopheles funestus AFUN005050 I 0.894
AFAF009162 Anopheles farauti AFAF009162 I 0.894
AEPI011485 Anopheles epiroticus AEPI011485 I 0.894
ADIR001683 Anopheles dirus ADIR001683 I 0.894
AQUA014034 Anopheles quadriannulatus AQUA014034 I 0.894
ASIS019843 Anopheles sinensis ASIS019843 I 0.894
ASTEI10641 Anopheles stephensi ASTEI10641 I 0.894
HPBE_0000907401 Heligmosomoides bakeri HPBE_0000907401 I 0.851
BXY_0231500 Bursaphelenchus xylophilus BXY_0231500 I 0.864
ACAC_0000390701 Angiostrongylus cantonensis ACAC_0000390701 I 0.851
PPAI007861 Phlebotomus papatasi PPAI007861 I 0.894
MDOA013398 Musca domestica MDOA013398 I 0.891
MDOA007431 Musca domestica MDOA007431 I 0.891
LLOJ002704 Lutzomyia longipalpis LLOJ002704 I 0.894
BGLB013717 Biomphalaria glabrata BGLB013717 I 0.894
ACUA026679 Anopheles culicifacies ACUA026679 I 0.894
ACUA009159 Anopheles culicifacies ACUA009159 I 0.894
Ocbimv22001940m.g Octopus bimaculoides Ocbimv22001940m.g I 0.894
Pvit_07565 Pogona vitticeps Pvit_07565 I 0.894
Ogr08231 Ophisaurus gracilis Ogr08231 I 0.894
Hsal_11874--XP_001122281.1_APIME Harpegnathos saltator Hsal_11874--XP_001122281.1_APIME I 0.914
Gfo_R014815 Geospiza fortis Gfo_R014815 I 0.894
ENSP00000405915 Macaca fascicularis ENSP00000405915 I 0.914
ENSP00000358519-D1 Bos grunniens ENSP00000358519-D1 I 0.914
ENSP00000302189 Macaca fascicularis ENSP00000302189 I 0.914
Sakowv30004475m.g Saccoglossus kowalevskii Sakowv30004475m.g I 0.894
CLEC002464 Cimex lectularius CLEC002464 I 0.894
LCUP012274 Lucilia cuprina LCUP012274 I 0.891
ACOM036372 Anopheles coluzzii ACOM036372 I 0.894
AATE010880 Anopheles atroparvus AATE010880 I 0.894
AARA003512 Anopheles arabiensis AARA003512 I 0.894
AALB004585 Anopheles albimanus AALB004585 I 0.894
nhlh1.L Xenopus laevis XB-GENE-989792 I 0.914
nhlh1.S Xenopus laevis XB-GENE-6252028 I 0.914
SMU15030866 Schmidtea mediterranea SMU15030866 I 0.857
LDEC000946 Leptinotarsa decemlineata LDEC000946 I 0.894
Cmyd_10014342 Chelonia mydas Cmyd_10014342 I 0.914
ENSMGAG00000016096 Meleagris gallopavo ENSMGAG00000016096 I 0.894
ENSFCAG00000028313 Felis catus ENSFCAG00000028313 I 0.914
ENSFALG00000006103 Ficedula albicollis ENSFALG00000006103 I 0.914
NHLH1 Echinops telfairi ENSETEG00000009677 I 0.914
NHLH1 Equus caballus ENSECAG00000004612 I 0.914
NHLH1 Dasypus novemcinctus ENSDNOG00000038600 I 0.914
NHLH2 Dasypus novemcinctus ENSDNOG00000008961 I 0.914
nhlh2 Danio rerio ENSDARG00000025495 I 0.894
ENSCSAG00000000172 Chlorocebus sabaeus ENSCSAG00000000172 I 0.914
nhlh2 Gasterosteus aculeatus ENSGACG00000014053 I 0.894
NHLH1 Gallus gallus ENSGALG00000025817 I 0.894
ENSMEUG00000003022 Macropus eugenii ENSMEUG00000003022 I 0.914
ENSLOCG00000017787 Lepisosteus oculatus ENSLOCG00000017787 I 0.894
NHLH1 Loxodonta africana ENSLAFG00000011163 I 0.914
NHLH2 Loxodonta africana ENSLAFG00000007456 I 0.914
ENSLACG00000011363 Latimeria chalumnae ENSLACG00000011363 I 0.914
ENSGMOG00000020309 Gadus morhua ENSGMOG00000020309 I 0.894
NHLH1 Gorilla gorilla ENSGGOG00000015736 I 0.914
NHLH2 Gorilla gorilla ENSGGOG00000008283 I 0.914
ENSCSAG00000000087 Chlorocebus sabaeus ENSCSAG00000000087 I 0.914
NHLH2 Cavia porcellus ENSCPOG00000026593 I 0.914
NHLH1 Cavia porcellus ENSCPOG00000021596 I 0.914
DAPPUDRAFT_66944 Daphnia pulex DAPPUDRAFT_66944 I 0.894
CGI_10002829 Crassostrea gigas CGI_10002829 I 0.870
CapteG162858 Capitella teleta CapteG162858 I 0.894
BGIBMGA008476 Bombyx mori BGIBMGA008476 I 0.894
AGAP004907 Anopheles gambiae AGAP004907 I 0.894
ADAC006978 Anopheles darlingi ADAC006978 I 0.894
ACYPI007008 Acyrthosiphon pisum ACYPI007008 I 0.894
ACEP10202 Atta cephalotes ACEP10202 I 0.914
NHLH2 Anolis carolinensis ENSACAG00000003304 I 0.914
ENSACAG00000010649 Anolis carolinensis ENSACAG00000010649 I 0.894
NHLH2 Callithrix jacchus ENSCJAG00000012807 I 0.914
NHLH1 Callithrix jacchus ENSCJAG00000005775 I 0.914
NHLH1 Canis familiaris ENSCAFG00000023513 I 0.914
NHLH2 Canis familiaris ENSCAFG00000009767 I 0.914
NHLH1 Bos taurus ENSBTAG00000020027 I 0.914
NHLH2 Bos taurus ENSBTAG00000015067 I 0.914
ENSAMXG00000026006 Astyanax mexicanus ENSAMXG00000026006 I 0.894
ENSAMEG00000010851 Ailuropoda melanoleuca ENSAMEG00000010851 I 0.890
AAEL004428 Aedes aegypti AAEL004428 I 0.894
ENSMICG00000002851 Microcebus murinus ENSMICG00000002851 I 0.914
ENSXMAG00000020348 Xiphophorus maculatus ENSXMAG00000020348 I 0.894
ENSSHAG00000015472 Sarcophilus harrisii ENSSHAG00000015472 I 0.914
ENSSHAG00000006613 Sarcophilus harrisii ENSSHAG00000006613 I 0.914
Nhlh2 Rattus norvegicus ENSRNOG00000054375 I 0.914
Nhlh1 Rattus norvegicus ENSRNOG00000005166 I 0.914
NHLH2 Pteropus vampyrus ENSPVAG00000012688 I 0.914
NHLH1 Pteropus vampyrus ENSPVAG00000007987 I 0.914
NHLH1 Pan troglodytes ENSPTRG00000001551 I 0.914
NHLH2 Pan troglodytes ENSPTRG00000001149 I 0.914
NHLH1 Sus scrofa ENSSSCG00000006384 I 0.914
NHLH2 Sus scrofa ENSSSCG00000006744 I 0.914
NHLH2 Tursiops truncatus ENSTTRG00000003112 I 0.914
NHLH1 Tursiops truncatus ENSTTRG00000001840 I 0.914
ENSTSYG00000000582 Tarsius syrichta ENSTSYG00000000582 I 0.914
nhlh2 Takifugu rubripes ENSTRUG00000003636 I 0.894
nhlh2 Tetraodon nigroviridis ENSTNIG00000010331 I 0.894
NHLH1 Taeniopygia guttata ENSTGUG00000013389 I 0.914
ENSSTOG00000027988 Ictidomys tridecemlineatus ENSSTOG00000027988 I 0.914
ENSSTOG00000019698 Ictidomys tridecemlineatus ENSSTOG00000019698 I 0.914
ENSPPYG00000000988 Pongo abelii ENSPPYG00000000988 I 0.914
ENSPPYG00000000632 Pongo abelii ENSPPYG00000000632 I 0.914
ENSPFOG00000020651 Poecilia formosa ENSPFOG00000020651 I 0.894
ENSNLEG00000013637 Nomascus leucogenys ENSNLEG00000013637 I 0.914
ENSMPUG00000019473 Mustela putorius furo ENSMPUG00000019473 I 0.914
ENSMPUG00000019387 Mustela putorius furo ENSMPUG00000019387 I 0.914
NHLH1 Monodelphis domestica ENSMODG00000024591 I 0.914
NHLH2 Monodelphis domestica ENSMODG00000023228 I 0.914
NHLH1 Macaca mulatta ENSMMUG00000021865 I 0.914
ENSMMUG00000008971 Macaca mulatta ENSMMUG00000008971 I 0.914
NHLH2 Myotis lucifugus ENSMLUG00000015989 I 0.914
NHLH2 Ornithorhynchus anatinus ENSOANG00000009820 I 0.914
NHLH2 Oryctolagus cuniculus ENSOCUG00000015744 I 0.914
NHLH1 Procavia capensis ENSPCAG00000009061 I 0.914
ENSPANG00000011970 Papio anubis ENSPANG00000011970 I 0.914
ENSPANG00000001481 Papio anubis ENSPANG00000001481 I 0.914
NHLH2 Ochotona princeps ENSOPRG00000006661 I 0.914
ENSONIG00000021015 Oreochromis niloticus ENSONIG00000021015 I 0.894
ENSONIG00000020673 Oreochromis niloticus ENSONIG00000020673 I 0.866
NHLH2 Otolemur garnettii ENSOGAG00000034540 I 0.914
NHLH1 Otolemur garnettii ENSOGAG00000010592 I 0.914
NHLH1 Microcebus murinus ENSMICG00000012700 I 0.914