BZIP28 (Arabidopsis thaliana)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 AT3G10800 T056893_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Encodes bZIP28, a putative membrane-tethered transcriptional factor. Up-regulated in response to heat; a bZIP28 null mutant has a heat-sensitive phenotype. bZIP28 has a similar domain structure to the mammalian ATF6 protein involved in the unfolded protein response (UPR), and shares a bZIP domain, transmembrane domain, and a canonical S1P cleavage site. The bZIP28 seems to be glycosylated in vivo. bZIP28 does not appear to be transcriptionally up-regulated by UPR-inducing tunicamycin (TM) treatment. But, the expression level of three UPR-related genes is reduced in TM-treated zip28 mutants relative to wild type seedlings. And several UPR genes are transcriptionally upregulated when an N-terminal portion of the bZIP28 protein is expressed using the 35S promoter. A myc:bZIP28 fusion protein appears to be cleaved, likely at a canonical S2 cleavage site, following a TM treatment or a DTT stress-inducing treatment, but not a salt treatment. A portion of the mGFP:bZIP28 protein present in root cells appears to translocate from the cytoplasm and ER to the nucleus following TM treatment.

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
BZIP28
M06772_2.00
Arabidopsis thaliana
DNNDRWSACGTGKCD

HGMCACGTSWYHNNH
Dap-seq
OMalley et al.(2016)
bZIP28_col_a
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AT3G10800.1 bZIP 188 251

Links

Other bZIP family TFs
Other Arabidopsis thaliana TFs

4 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
BZIP28 Arabidopsis lyrata fgenesh2_kg.3__1116__AT3G10800.1 I 0.890
Cagra.8632s0019 Capsella grandiflora Cagra.8632s0019 I 0.880
Carubv10016005m.g Capsella rubella Carubv10016005m.g I 0.880
Bostr.19424s1002 Boechera stricta Bostr.19424s1002 I 0.857