HY5 (Arabidopsis thaliana)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 AT5G11260 T056924_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Basic leucine zipper (bZIP) transcription factor. Nuclear localization. Involved in light-regulated transcriptional activation of G-box-containing promoters. Negatively regulated by Cop1. Although cytokinins do not appear to affect the gene's promoter activity, they appear to stabilize the protein. HY5 plays a role in anthocyanin accumulation in far-red light and blue light, but not in red light or in the dark. Mutant studies showed that the gene product is involved in the positive regulation of the PHYA-mediated inhibition of hypocotyl elongation. Binds to G- and Z-boxes, and other ACEs, but not to E-box. Loss of function mutation shows ABA resistant seedling phenotypes suggesting involvement for HY5 in mediating ABA responses. Binds to the promoter of ABI5 and regulates its expression.

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HY5
M06790_2.00		 Arabidopsis thaliana
DNHGVTGACGTSDMN
NKHSACGTCABCDNH		 Dap-seq
OMalley et al.(2016)
HY5_colamp_v3a		 (Direct) (Direct)
HY5
M08407_2.00		 Arabidopsis thaliana
NNHGMCACGTGKCDNN
NNHGMCACGTGKCDNN		 ChIP-chip
Mathelier et al.(2014)
MA0551.1		 (Direct) (Direct)
HY5
M09919_2.00		 Arabidopsis thaliana Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
P$HY5_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Q39895_SOYBN
M10048_2.00 		Glycine max Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
P$STF1_01 		0.831 0.841
Q39895_SOYBN
M10049_2.00 		Glycine max Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
P$STF1_02 		0.831 0.841
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AT5G11260.1 bZIP 86 150
AT5G11260.2 bZIP 86 148

Links

Other bZIP family TFs
Other Arabidopsis thaliana TFs

Invalid Input OrderBy

104 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action