CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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HY5
(
Arabidopsis thaliana
)
bZIP
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00170 (bZIP_1)
IPR011616
AT5G11260
T056924_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Basic leucine zipper (bZIP) transcription factor. Nuclear localization. Involved in light-regulated transcriptional activation of G-box-containing promoters. Negatively regulated by Cop1. Although cytokinins do not appear to affect the gene's promoter activity, they appear to stabilize the protein. HY5 plays a role in anthocyanin accumulation in far-red light and blue light, but not in red light or in the dark. Mutant studies showed that the gene product is involved in the positive regulation of the PHYA-mediated inhibition of hypocotyl elongation. Binds to G- and Z-boxes, and other ACEs, but not to E-box. Loss of function mutation shows ABA resistant seedling phenotypes suggesting involvement for HY5 in mediating ABA responses. Binds to the promoter of ABI5 and regulates its expression.
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
HY5
M06790_2.00
Arabidopsis thaliana
DNHGVTGACGTSDMN
NKHSACGTCABCDNH
Dap-seq
OMalley et al.(2016)
HY5_colamp_v3a
(Direct)
(Direct)
HY5
M08407_2.00
Arabidopsis thaliana
NNHGMCACGTGKCDNN
NNHGMCACGTGKCDNN
ChIP-chip
Mathelier et al.(2014)
MA0551.1
(Direct)
(Direct)
HY5
M09919_2.00
Arabidopsis thaliana
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
P$HY5_01
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Q39895_SOYBN
M10048_2.00
Glycine max
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
P$STF1_01
0.857
0.875
Q39895_SOYBN
M10049_2.00
Glycine max
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
P$STF1_02
0.831
0.841
For this family, TFs with SR scores >
0.782
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
AT5G11260.1
bZIP
86
150
EKENKRLKRLLRNRVSAQQARERKKAYLSELENRVKDLENKNSELEERLSTLQNENQMLRHILKN
AT5G11260.2
bZIP
86
148
EKENKRLKRLLRNRVSAQQARERKKAYLSELENRVKDLENKNSELEERLSTLQNENQMLRHVR
Links
Other
bZIP
family TFs
Other
Arabidopsis thaliana
TFs
104 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy