atf6 (Danio rerio)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSDARG00000012656 T059387_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within endoplasmic reticulum unfolded protein response and response to hypoxia. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in nucleus. Is expressed in brain; head; liver; and trunk. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ATF6
M04254_2.00 		Homo sapiens
YKRTGACGTGGCAN
NTGCCACGTCAYMR		 SELEX
Yin et al.(2017)
ATF6_eDBD_HT-SELEX_1 		0.835 0.688
ATF6
M04255_2.00 		Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN		 SELEX
Yin et al.(2017)
ATF6_eDBD_HT-SELEX_2 		0.835 0.688
ATF6
M04018_2.00 		Homo sapiens
GRTGACGTGGCR
YGCCACGTCAYC		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6.1 		0.835 0.688
ATF6
M04019_2.00 		Homo sapiens
KAGTCACGTGK
MCACGTGACTM		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6.2 		0.835 0.688
ATF6
M04020_2.00 		Homo sapiens
BNRTGACGTCATCA
TGATGACGTCAYNV		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6.3 		0.835 0.688
ATF6
M04021_2.00 		Homo sapiens
ACCACGATGTY
RACATCGTGGT		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6.4 		0.835 0.688
ATF6
M08790_2.00 		Homo sapiens
VBSSTGACGTGG
CCACGTCASSVB		 Misc
Kulakovskiy et al.(2013)
ATF6A_HUMAN.H11MO.0.B 		0.835 0.688
ATF6
M09947_2.00 		Homo sapiens
TGACGTGG
CCACGTCA		 Transfac
Matys et al.(2006)
V$ATF6_01 		0.835 0.688
ATF6
M04256_2.00 		Homo sapiens
YGRTGACGTGGCRN
NYGCCACGTCAYCR		 SELEX
Yin et al.(2017)
ATF6_eDBD_Methyl-HT-SELEX_1 		0.835 0.688
ATF6
M04257_2.00 		Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN		 SELEX
Yin et al.(2017)
ATF6_eDBD_Methyl-HT-SELEX_2 		0.835 0.688
ATF6B
M04375_2.00 		Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN		 SELEX
Yin et al.(2017)
ATF6B_eDBD_HT-SELEX_1 		0.824 0.562
ATF6B
M04376_2.00 		Homo sapiens
NRTGACGTGGCR
YGCCACGTCAYN		 SELEX
Yin et al.(2017)
ATF6B_eDBD_HT-SELEX_2 		0.824 0.562
ATF6B
M04377_2.00 		Homo sapiens
TGCCACGTGGCR
YGCCACGTGGCA		 SELEX
Yin et al.(2017)
ATF6B_eDBD_HT-SELEX_3 		0.824 0.562
ATF6B
M04041_2.00 		Homo sapiens
GRTGACGTGGCR
YGCCACGTCAYC		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6B.1 		0.824 0.562
ATF6B
M04042_2.00 		Homo sapiens
YGMCACGTGKCR
YGMCACGTGKCR		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6B.2 		0.824 0.562
ATF6B
M04043_2.00 		Homo sapiens
RTGACGTCAYC
GRTGACGTCAY		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6B.3 		0.824 0.562
ATF6B
M04044_2.00 		Homo sapiens
MCCACGATGT
ACATCGTGGK		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6B.4 		0.824 0.562
ATF6B
M04378_2.00 		Homo sapiens
SRTGACGTCAYB
VRTGACGTCAYS		 SELEX
Yin et al.(2017)
ATF6B_eDBD_Methyl-HT-SELEX_1 		0.824 0.562
ATF6B
M04379_2.00 		Homo sapiens
BRTGACGTGGCR
YGCCACGTCAYV		 SELEX
Yin et al.(2017)
ATF6B_eDBD_Methyl-HT-SELEX_2 		0.824 0.562
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000009333 bZIP 290 353

Links

Other bZIP family TFs
Other Danio rerio TFs

Invalid Input OrderBy

114 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action