NFE2 (Homo sapiens)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSG00000123405 T059736_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
NFE2
M02832_2.00
Homo sapiens
VATGACTCATB

VATGAGTCATB
SELEX
Jolma et al.(2013)
NFE2_1
(Direct) (Direct)
NFE2
M04024_2.00
Homo sapiens
RTGACTCAY

RTGAGTCAY
SELEX
Rodriguez-Martinez et al.(2017)
NFE2.1
(Direct) (Direct)
NFE2
M04266_2.00
Homo sapiens
VRTGASTCAYB

VRTGASTCAYB
SELEX
Yin et al.(2017)
NFE2_eDBD_HT-SELEX
(Direct) (Direct)
NFE2
M04267_2.00
Homo sapiens
NRTGASTCAYN

NRTGASTCAYN
SELEX
Yin et al.(2017)
NFE2_eDBD_Methyl-HT-SELEX
(Direct) (Direct)
NFE2
M07813_2.00
Homo sapiens
VRTGACTCAGCANWWHB

VDWWNTGCTGAGTCAYB
ChIP-seq
Gerstein et al.(2012)
K562_NFE2_Stanford
(Direct) (Direct)
NFE2
M08793_2.00
Homo sapiens
VVRTGACTCAGCA

TGCTGAGTCAYBB
Misc
Kulakovskiy et al.(2013)
NFE2_HUMAN.H11MO.0.A
(Direct) (Direct)
NFE2
M09486_2.00
Homo sapiens
VATGACTCAGCA

TGCTGAGTCATB
Misc
Heinz et al.(2010)
K562-NFE2_GSE31477
(Direct) (Direct)
NFE2
M09959_2.00
Homo sapiens
RTGASTCAGCD

HGCTGASTCAY
Transfac
Matys et al.(2006)
V$NFE2_01
(Direct) (Direct)
NFE2
M09960_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NFE2_04
(Direct) (Direct)
NFE2
M09961_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NFE2_Q6
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Nfe2
M08843_2.00
Mus musculus
RTGACTCAGCANDW

WHNTGCTGAGTCAY
Misc
Kulakovskiy et al.(2013)
NFE2_MOUSE.H11MO.0.A
0.915 0.952
NFE2L2
M01142_2.00
Gallus gallus
NNRTKAYNN

NNRTMAYNN
PBM
Lambert et al.(2019)
pTH9845
0.868 0.683
NFE2L2
M08789_2.00
Homo sapiens
RTGACTCAGCANWW

WWNTGCTGAGTCAY
Misc
Kulakovskiy et al.(2013)
NF2L2_HUMAN.H11MO.0.A
0.868 0.635
NFE2L2
M09943_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF2_Q3
0.868 0.635
NFE2L2
M09944_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF2_Q4_01
0.868 0.635
NFE2L2
M09945_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF2_Q4
0.868 0.635
NFE2L2
M09946_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF2_Q6
0.868 0.635
Nfe2l2
M08077_2.00
Mus musculus
NRNNRTGACTCAGCA

TGCTGAGTCAYNNYN
ChIP-seq
Mathelier et al.(2014)
MA0150.2
0.858 0.667
Nfe2l2
M08816_2.00
Mus musculus
RTGACTNAGCANDH

DHNTGCTNAGTCAY
Misc
Kulakovskiy et al.(2013)
NF2L2_MOUSE.H11MO.0.A
0.858 0.667
NFE2L1
M04008_2.00
Homo sapiens
RTGACTCAY

RTGAGTCAY
SELEX
Rodriguez-Martinez et al.(2017)
NFE2L1.1
0.832 0.587
NFE2L1
M08782_2.00
Homo sapiens
NATGAYD

HRTCATN
Misc
Kulakovskiy et al.(2013)
NF2L1_HUMAN.H11MO.0.C
0.832 0.587
Nfe2l1
M08831_2.00
Mus musculus
NATGAYD

HRTCATN
Misc
Kulakovskiy et al.(2013)
NF2L1_MOUSE.H11MO.0.C
0.832 0.587
NFE2L1
M09925_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NFE2L1_Q5
0.832 0.587
NFE2L1
M09926_2.00
Homo sapiens
NNNNHWNNATGAC

GTCATNNWDNNNN
Transfac
Matys et al.(2006)
V$TCF11_01
0.832 0.587
Nfe2l3
M10031_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF3_01
0.828 0.508
NFE2L3
M09923_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF3_02
0.815 0.508
FBgn0262975
M03654_2.00
Drosophila melanogaster
NYGTCAYSRTGACRN

NYGTCAYSRTGACRN
SELEX
Nitta et al.(2015)
cnc_1
0.791 0.444
FBgn0262975
M03655_2.00
Drosophila melanogaster
SATGACRNVVATGACD

HGTCATBBNYGTCATS
SELEX
Nitta et al.(2015)
cnc_2
0.791 0.444
FBgn0262975
M03656_2.00
Drosophila melanogaster
GTCAKSATGACGTCAY

RTGACGTCATSMTGAC
SELEX
Nitta et al.(2015)
cnc_3
0.791 0.444
FBgn0262975
M08189_2.00
Drosophila melanogaster
TGAYTBDGCA

TGCHVARTCA
ChIP-seq
Contrino et al.(2012)
Mf3
0.791 0.444
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000312436 bZIP 265 327
ENSP00000397185 bZIP 265 327
ENSP00000439120 bZIP 265 327
ENSP00000446929 bZIP 265 327
ENSP00000447558 bZIP 265 327

Links

Other bZIP family TFs
Other Homo sapiens TFs

328 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSCSAG00000018675 Chlorocebus sabaeus ENSCSAG00000018675 I 0.000
ENSMPUG00000001216 Mustela putorius furo ENSMPUG00000001216 I 0.000
ENSPANG00000017142 Papio anubis ENSPANG00000017142 I 0.000
ENSPPYG00000010750 Pongo abelii ENSPPYG00000010750 I 0.000
INSM1 Pan troglodytes ENSPTRG00000013303 I 0.000
INSM1 Otolemur garnettii ENSOGAG00000034802 I 0.000
Insm1 Mus musculus ENSMUSG00000068154 D 0.000
INSM1 Bos taurus ENSBTAG00000045526 I 0.000
INSM1 Gorilla gorilla ENSGGOG00000027642 I 0.000
INSM1 Homo sapiens ENSG00000173404 D 0.000
INSM1 Dasypus novemcinctus ENSDNOG00000033318 I 0.000
INSM1 Canis familiaris ENSCAFG00000005264 I 0.000
INSM1 Sus scrofa ENSSSCG00000007106 I 0.000