CREB3L4 (Homo sapiens)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSG00000143578 T059744_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CREB3L4
M04293_2.00		 Homo sapiens
NRTGACGTCABN
NVTGACGTCAYN		 SELEX
Yin et al.(2017)
CREB3L4_eDBD_HT-SELEX_1		 (Direct) (Direct)
CREB3L4
M04294_2.00		 Homo sapiens
NKCCACGTCABN
NVTGACGTGGMN		 SELEX
Yin et al.(2017)
CREB3L4_eDBD_HT-SELEX_2		 (Direct) (Direct)
CREB3L4
M04295_2.00		 Homo sapiens
NDMVACGTGKMH
DKMCACGTBKHN		 SELEX
Yin et al.(2017)
CREB3L4_eDBD_HT-SELEX_3		 (Direct) (Direct)
CREB3L4
M04296_2.00		 Homo sapiens
NVTGACRTCAYV
BRTGAYGTCABN		 SELEX
Yin et al.(2017)
CREB3L4_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
CREB3L4
M04297_2.00		 Homo sapiens
DGMSACGTGKCR
YGMCACGTSKCH		 SELEX
Yin et al.(2017)
CREB3L4_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
CREB3L4
M04298_2.00		 Homo sapiens
YKCCACRTCAYM
KRTGAYGTGGMR		 SELEX
Yin et al.(2017)
CREB3L4_eDBD_Methyl-HT-SELEX_3		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CREB3L2
M01143_2.00 		Monodelphis domestica
NACGTGKH
DMCACGTN		 PBM
Lambert et al.(2019)
pTH11415 		0.785 0.594
Creb3l2
M01812_2.00 		Mus musculus
HCACGTGKM
KMCACGTGD		 PBM
Weirauch et al.(2014)
pTH5024 		0.785 0.594
Creb3l2
M02863_2.00 		Mus musculus
TGRTGACGTGGCA
TGCCACGTCAYCA		 SELEX
Jolma et al.(2013)
Creb3l2_1 		0.785 0.594
Creb3l2
M02864_2.00 		Mus musculus
KGCCACGTGGCA
TGCCACGTGGCM		 SELEX
Jolma et al.(2013)
Creb3l2_2 		0.785 0.594
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000271889 bZIP 215 291
ENSP00000357589 bZIP 195 272
ENSP00000357592 bZIP 215 291
ENSP00000357596 bZIP 215 291
ENSP00000391847 bZIP 195 228

Links

Other bZIP family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

126 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action