TF Information

NFIL3 *(Homo sapiens)* bZIP
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00170 (bZIP_1)	IPR011616	ENSG00000165030	T059751_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and PER2 expression and therefore plays a role in the regulation of circadian rhythm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
NFIL3 M02658_2.00	Homo sapiens	TTAYGTAABNN	NNVTTACRTAA	SELEX Mathelier et al.(2014) MA0025.1	(Direct)	(Direct)
NFIL3 M02848_2.00	Homo sapiens	NVTTACRTAAYN	NRTTAYGTAABN	SELEX Jolma et al.(2013) NFIL3_1	(Direct)	(Direct)
NFIL3 M04034_2.00	Homo sapiens	RTKAYGTAAY	RTTACRTMAY	SELEX Rodriguez-Martinez et al.(2017) NFIL3.1	(Direct)	(Direct)
NFIL3 M09982_2.00	Homo sapiens	NRTTAYGTAABN	NVTTACRTAAYN	Transfac Matys et al.(2006) V$E4BP4_01	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Nfil3 M01819_2.00	Mus musculus	NRTTAYVNNN	NNNBRTAAYN	PBM Weirauch et al.(2014) pTH5082	0.829	1.000
Nfil3 M08842_2.00	Mus musculus	DRTKATGYAAB	VTTRCATMAYH	Misc Kulakovskiy et al.(2013) NFIL3_MOUSE.H11MO.0.C	0.829	1.000
For this family, TFs with SR scores > 0.782* will likely have a similar motif*