CEBPD (Homo sapiens)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSG00000221869 T059769_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
CEBPD
M02859_2.00
Homo sapiens
VTTRCGCAAY

RTTGCGYAAB
SELEX
Jolma et al.(2013)
CEBPD_1
(Direct) (Direct)
CEBPD
M04380_2.00
Homo sapiens
NVTTRCGCAAYN

NRTTGCGYAABN
SELEX
Yin et al.(2017)
CEBPD_eDBD_HT-SELEX
(Direct) (Direct)
CEBPD
M04381_2.00
Homo sapiens
NRTTRCGCAAYN

NRTTGCGYAAYN
SELEX
Yin et al.(2017)
CEBPD_eDBD_Methyl-HT-SELEX
(Direct) (Direct)
CEBPD
M08812_2.00
Homo sapiens
DVTKRHGCAAB

VTTGCDYMABH
Misc
Kulakovskiy et al.(2013)
CEBPD_HUMAN.H11MO.0.C
(Direct) (Direct)
CEBPD
M10020_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPD_Q3
(Direct) (Direct)
CEBPD
M10021_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPD_Q6_01
(Direct) (Direct)
CEBPD
M10022_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPD_Q6
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Cebpd
M00990_2.00
Mus musculus
TTRCGCAA

TTGCGYAA
PBM
Mann et al.(2013)
CEBPD_UM_HK
0.883 1.000
Cebpd
M01789_2.00
Mus musculus
NDDNRHAAB

VTTDYNHHN
PBM
Weirauch et al.(2014)
pTH5250
0.883 1.000
Cebpd
M08780_2.00
Mus musculus
NVTKDNGMAAK

MTTKCNHMABN
Misc
Kulakovskiy et al.(2013)
CEBPD_MOUSE.H11MO.0.B
0.883 1.000
Cebpd
M00989_2.00
Mus musculus
NTTDCGCAA

TTGCGHAAN
PBM
Mann et al.(2013)
CEBPD_M_HK
0.883 1.000
Cebpd
M10034_2.00
Rattus norvegicus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPD_02
0.883 0.983
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000386165 bZIP 194 252

Links

Other bZIP family TFs
Other Homo sapiens TFs

37 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
CEBPD Pan troglodytes ENSPTRG00000042020 I 0.883
CEBPD Macaca mulatta ENSMMUG00000013151 I 0.883
Cebpd Rattus norvegicus ENSRNOG00000050869 D 0.883
ENSSTOG00000021236 Ictidomys tridecemlineatus ENSSTOG00000021236 I 0.883
ENSMPUG00000001146 Mustela putorius furo ENSMPUG00000001146 I 0.883
ENSPPYG00000018572 Pongo abelii ENSPPYG00000018572 I 0.883
CEBPD Otolemur garnettii ENSOGAG00000030449 I 0.883
ENSOCUG00000025135 Oryctolagus cuniculus ENSOCUG00000025135 I 0.883
Cebpd Mus musculus BAE29047.1 D 0.883
cebpd.S Xenopus laevis XB-GENE-866497 I 0.883
CEBPD Gorilla gorilla ENSGGOG00000008077 I 0.883
ENSCPOG00000025482 Cavia porcellus ENSCPOG00000025482 I 0.883
CEBPD Callithrix jacchus ENSCJAG00000013678 I 0.883
ENSAPLG00000002650 Anas platyrhynchos ENSAPLG00000002650 I 0.883
ENSPANG00000024953 Papio anubis ENSPANG00000024953 I 0.883
Cmyd_10014862 Chelonia mydas Cmyd_10014862 I 0.883
CEBPD Taeniopygia guttata ENSTGUG00000010839 I 0.883
CEBPD Dasypus novemcinctus ENSDNOG00000025666 I 0.883
cebpd Gasterosteus aculeatus ENSGACG00000017927 I 0.876
cebpd.L Xenopus laevis XB-GENE-17330367 I 0.874
Pvit_15371 Pogona vitticeps Pvit_15371 I 0.872
ENSOANG00000007261 Ornithorhynchus anatinus ENSOANG00000007261 I 0.870
CEBPD Monodelphis domestica ENSMODG00000010525 I 0.870
cebpd Xenopus tropicalis XB-GENE-853588 I 0.870
cebpd Tetraodon nigroviridis ENSTNIG00000000222 I 0.864
ENSXMAG00000019437 Xiphophorus maculatus ENSXMAG00000019437 I 0.860
ENSSSCG00000006276 Sus scrofa ENSSSCG00000006276 I 0.860
ENSPFOG00000020361 Poecilia formosa ENSPFOG00000020361 I 0.860
ENSFALG00000014184 Ficedula albicollis ENSFALG00000014184 I 0.857
ENSAMXG00000025594 Astyanax mexicanus ENSAMXG00000025594 I 0.854
CEBPD Anolis carolinensis ENSACAG00000012009 I 0.852
ENSONIG00000021429 Oreochromis niloticus ENSONIG00000021429 I 0.848
cebpd Danio rerio ENSDARG00000087303 I 0.839
ENSLACG00000015084 Latimeria chalumnae ENSLACG00000015084 I 0.834
ENSLOCG00000017816 Lepisosteus oculatus ENSLOCG00000017816 I 0.834
ENSOARG00000011169 Ovis aries ENSOARG00000011169 I 0.826
ENSGMOG00000002585 Gadus morhua ENSGMOG00000002585 I 0.825