CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Fosb
(
Mus musculus
)
bZIP
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00170 (bZIP_1)
IPR011616
ENSMUSG00000003545
T060453_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within cellular response to calcium ion. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; gut; male reproductive gland or organ; skin; and urinary system. Orthologous to human FOSB (FosB proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Fosb
M08814_2.00
Mus musculus
VTGACTCAB
VTGAGTCAB
Misc
Kulakovskiy et al.(2013)
FOSB_MOUSE.H11MO.0.A
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
FOSB
M04272_2.00
Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN
SELEX
Yin et al.(2017)
FOSB_eDBD_HT-SELEX
0.916
1.000
FOSB
M08795_2.00
Homo sapiens
VTGACTCAB
VTGAGTCAB
Misc
Kulakovskiy et al.(2013)
FOSB_HUMAN.H11MO.0.A
0.916
1.000
FOSB
M04273_2.00
Homo sapiens
NRTGACRTCAYN
NRTGAYGTCAYN
SELEX
Yin et al.(2017)
FOSB_eDBD_Methyl-HT-SELEX
0.916
1.000
Fosl2
M01809_2.00
Mus musculus
GATGACKH
DMGTCATC
PBM
Weirauch et al.(2014)
pTH5108
0.889
0.836
Fosl2
M08828_2.00
Mus musculus
NVTGACTCABN
NVTGAGTCABN
Misc
Kulakovskiy et al.(2013)
FOSL2_MOUSE.H11MO.0.A
0.889
0.836
Fosl2
M09494_2.00
Mus musculus
NNVTGASTCABN
NVTGASTCABNN
Misc
Heinz et al.(2010)
3T3L1-Fosl2_GSE56872
0.889
0.836
FOS
M04327_2.00
Homo sapiens
BRTGACGTCAYV
BRTGACGTCAYV
SELEX
Yin et al.(2017)
FOS_eDBD_HT-SELEX
0.884
0.820
FOS
M08069_2.00
Homo sapiens
DVTGASTCATN
NATGASTCABH
ChIP-seq
Mathelier et al.(2014)
MA0476.1
0.884
0.820
FOS
M07826_2.00
Homo sapiens
NATGASTCABDBN
NVHVTGASTCATN
ChIP-seq
Gerstein et al.(2012)
HeLa-S3_CFOS_Stanford
0.884
0.820
FOS
M07827_2.00
Homo sapiens
MTGASTCAYHN
NDRTGASTCAK
ChIP-seq
Gerstein et al.(2012)
HUVEC_CFOS_UCD
0.884
0.820
FOS
M07828_2.00
Homo sapiens
BDRTGASTCAYNBHB
VDVNRTGASTCAYHV
ChIP-seq
Gerstein et al.(2012)
K562_CFOS_UChicago
0.884
0.820
FOS
M08802_2.00
Homo sapiens
VTGACTCAB
VTGAGTCAB
Misc
Kulakovskiy et al.(2013)
FOS_HUMAN.H11MO.0.A
0.884
0.820
Fos
M08819_2.00
Mus musculus
NRTGACTCAYNN
NNRTGAGTCAYN
Misc
Kulakovskiy et al.(2013)
FOS_MOUSE.H11MO.0.A
0.884
0.820
FOS
M09988_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CFOS_Q4
0.884
0.820
FOS
M09989_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CFOS_Q6
0.884
0.820
FOS
M09990_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FOS_02
0.884
0.820
FOS
M09991_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FOS_03
0.884
0.820
FOS
M04328_2.00
Homo sapiens
VATGACRTCAYM
KRTGAYGTCATB
SELEX
Yin et al.(2017)
FOS_eDBD_Methyl-HT-SELEX
0.884
0.820
Fosl1
M01805_2.00
Mus musculus
NNRTGACKYMN
NKRMGTCAYNN
PBM
Weirauch et al.(2014)
pTH5077
0.799
0.803
FOSL1
M04333_2.00
Homo sapiens
NRTGAWTCAYN
NRTGAWTCAYN
SELEX
Yin et al.(2017)
FOSL1_FL_HT-SELEX_1
0.799
0.803
FOSL1
M04334_2.00
Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN
SELEX
Yin et al.(2017)
FOSL1_FL_HT-SELEX_2
0.799
0.803
FOSL1
M04335_2.00
Homo sapiens
DRTGAYRCR
YGYRTCAYH
SELEX
Yin et al.(2017)
FOSL1_FL_HT-SELEX_3
0.799
0.803
FOSL1
M04035_2.00
Homo sapiens
RTGACGTCAY
RTGACGTCAY
SELEX
Rodriguez-Martinez et al.(2017)
FOSL1.1
0.799
0.803
FOSL1
M04036_2.00
Homo sapiens
GTCAYCRRTGAC
GTCAYYGRTGAC
SELEX
Rodriguez-Martinez et al.(2017)
FOSL1.2
0.799
0.803
FOSL1
M08071_2.00
Homo sapiens
DRTGASTCAKV
BMTGASTCAYH
ChIP-seq
Mathelier et al.(2014)
MA0477.1
0.799
0.803
FOSL1
M07833_2.00
Homo sapiens
NDRTGASTCAB
VTGASTCAYHN
ChIP-seq
Gerstein et al.(2012)
K562_FOSL1_HudsonAlpha
0.799
0.803
FOSL1
M08805_2.00
Homo sapiens
NVTGACTCABNN
NNVTGAGTCABN
Misc
Kulakovskiy et al.(2013)
FOSL1_HUMAN.H11MO.0.A
0.799
0.803
Fosl1
M08821_2.00
Mus musculus
NVTGACTCABNN
NNVTGAGTCABN
Misc
Kulakovskiy et al.(2013)
FOSL1_MOUSE.H11MO.0.A
0.799
0.803
FOSL1
M09490_2.00
Homo sapiens
NNVTGASTCABN
NVTGASTCABNN
Misc
Heinz et al.(2010)
BT549-Fra1_GSE46166
0.799
0.803
FOSL1
M10000_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FOSL1_01
0.799
0.803
FOSL1
M10001_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FRA1_Q5
0.799
0.803
FOSL1
M10002_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FRA1_Q6_01
0.799
0.803
FOSL1
M10003_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FRA1_Q6
0.799
0.803
FOSL1
M04336_2.00
Homo sapiens
BRTGASTCATV
BATGASTCAYV
SELEX
Yin et al.(2017)
FOSL1_FL_Methyl-HT-SELEX_1
0.799
0.803
FOSL1
M04337_2.00
Homo sapiens
NRTSACGTCAYN
NRTGACGTSAYN
SELEX
Yin et al.(2017)
FOSL1_FL_Methyl-HT-SELEX_2
0.799
0.803
FOSL1
M04338_2.00
Homo sapiens
RATGAYRCR
YGYRTCATY
SELEX
Yin et al.(2017)
FOSL1_FL_Methyl-HT-SELEX_3
0.799
0.803
Atf3
M03648_2.00
Drosophila melanogaster
NRTKACGTMAYN
NRTKACGTMAYN
SELEX
Nitta et al.(2015)
Atf3_1
0.783
0.426
For this family, TFs with SR scores >
0.782
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSMUSP00000003640
bZIP
153
213
EEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEF
Links
Other
bZIP
family TFs
Other
Mus musculus
TFs
292 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy