Hlf (Mus musculus)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSMUSG00000003949 T060454_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within skeletal muscle cell differentiation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human HLF (HLF transcription factor, PAR bZIP family member). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hlf
M02860_2.00		 Mus musculus
KRTTACGTAAYN
NRTTACGTAAYM		 SELEX
Jolma et al.(2013)
Hlf_1		 (Direct) (Direct)
Hlf
M08815_2.00		 Mus musculus
VTTRTGYAABH
DVTTRCAYAAB		 Misc
Kulakovskiy et al.(2013)
HLF_MOUSE.H11MO.0.C		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HLF
M02831_2.00 		Homo sapiens
NRTTAYRTAABN
NVTTAYRTAAYN		 SELEX
Jolma et al.(2013)
HLF_1 		0.896 1.000
HLF
M04245_2.00 		Homo sapiens
NVTTRCRYAABN
NVTTRYGYAABN		 SELEX
Yin et al.(2017)
HLF_FL_HT-SELEX 		0.896 1.000
HLF
M04016_2.00 		Homo sapiens
RTKAYRTAAB
VTTAYRTMAY		 SELEX
Rodriguez-Martinez et al.(2017)
HLF.1 		0.896 1.000
HLF
M08786_2.00 		Homo sapiens
NRTTRYGTAAYMS
SKRTTACRYAAYN		 Misc
Kulakovskiy et al.(2013)
HLF_HUMAN.H11MO.0.C 		0.896 1.000
HLF
M09937_2.00 		Homo sapiens
ATKRYGTAAY
RTTACRYMAT		 Transfac
Matys et al.(2006)
V$HLF_01 		0.896 1.000
HLF
M04246_2.00 		Homo sapiens
NVTTRCRYAABN
NVTTRYGYAABN		 SELEX
Yin et al.(2017)
HLF_FL_Methyl-HT-SELEX 		0.896 1.000
Tef
M01803_2.00 		Mus musculus
NVTTRYVNNN
NNNBRYAABN		 PBM
Weirauch et al.(2014)
pTH5078 		0.847 0.794
TEF
M02849_2.00 		Homo sapiens
NRTTAYGTAAYN
NRTTACRTAAYN		 SELEX
Jolma et al.(2013)
TEF_1 		0.847 0.794
TEF
M02850_2.00 		Homo sapiens
NVTTAYGTAABN
NVTTACRTAABN		 SELEX
Jolma et al.(2013)
TEF_2 		0.847 0.794
TEF
M04325_2.00 		Homo sapiens
NRTTACGTAAYN
NRTTACGTAAYN		 SELEX
Yin et al.(2017)
TEF_eDBD_HT-SELEX 		0.847 0.794
TEF
M09983_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_05 		0.847 0.794
TEF
M09984_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_06 		0.847 0.794
TEF
M09985_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_Q6 		0.847 0.794
TEF
M09986_2.00 		Homo sapiens
MTKAYGTAAY
RTTACRTMAK		 Transfac
Matys et al.(2006)
V$VBP_01 		0.847 0.794
TEF
M04326_2.00 		Homo sapiens
NRTTACRTAAYN
NRTTAYGTAAYN		 SELEX
Yin et al.(2017)
TEF_eDBD_Methyl-HT-SELEX 		0.847 0.794
Pdp1
M03645_2.00 		Drosophila melanogaster
VTTACGTAAB
VTTACGTAAB		 SELEX
Nitta et al.(2015)
Pdp1_1 		0.795 0.683
Pdp1
M03646_2.00 		Drosophila melanogaster
RTTACGTAAY
RTTACGTAAY		 SELEX
Nitta et al.(2015)
Pdp1_2 		0.795 0.683
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000004051 bZIP 224 286

Links

Other bZIP family TFs
Other Mus musculus TFs

Invalid Input OrderBy

232 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action