Atf6b (Mus musculus)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSMUSG00000015461 T060455_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to contribute to DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in endoplasmic reticulum unfolded protein response; negative regulation of ATF6-mediated unfolded protein response; and positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress. Predicted to act upstream of or within response to unfolded protein. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of RNA polymerase II transcription regulator complex and protein-DNA complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human ATF6B (activating transcription factor 6 beta). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ATF6B
M04375_2.00 		Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN		 SELEX
Yin et al.(2017)
ATF6B_eDBD_HT-SELEX_1 		0.883 1.000
ATF6B
M04376_2.00 		Homo sapiens
NRTGACGTGGCR
YGCCACGTCAYN		 SELEX
Yin et al.(2017)
ATF6B_eDBD_HT-SELEX_2 		0.883 1.000
ATF6B
M04377_2.00 		Homo sapiens
TGCCACGTGGCR
YGCCACGTGGCA		 SELEX
Yin et al.(2017)
ATF6B_eDBD_HT-SELEX_3 		0.883 1.000
ATF6B
M04041_2.00 		Homo sapiens
GRTGACGTGGCR
YGCCACGTCAYC		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6B.1 		0.883 1.000
ATF6B
M04042_2.00 		Homo sapiens
YGMCACGTGKCR
YGMCACGTGKCR		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6B.2 		0.883 1.000
ATF6B
M04043_2.00 		Homo sapiens
RTGACGTCAYC
GRTGACGTCAY		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6B.3 		0.883 1.000
ATF6B
M04044_2.00 		Homo sapiens
MCCACGATGT
ACATCGTGGK		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6B.4 		0.883 1.000
ATF6B
M04378_2.00 		Homo sapiens
SRTGACGTCAYB
VRTGACGTCAYS		 SELEX
Yin et al.(2017)
ATF6B_eDBD_Methyl-HT-SELEX_1 		0.883 1.000
ATF6B
M04379_2.00 		Homo sapiens
BRTGACGTGGCR
YGCCACGTCAYV		 SELEX
Yin et al.(2017)
ATF6B_eDBD_Methyl-HT-SELEX_2 		0.883 1.000
ATF6
M04254_2.00 		Homo sapiens
YKRTGACGTGGCAN
NTGCCACGTCAYMR		 SELEX
Yin et al.(2017)
ATF6_eDBD_HT-SELEX_1 		0.832 0.625
ATF6
M04255_2.00 		Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN		 SELEX
Yin et al.(2017)
ATF6_eDBD_HT-SELEX_2 		0.832 0.625
ATF6
M04018_2.00 		Homo sapiens
GRTGACGTGGCR
YGCCACGTCAYC		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6.1 		0.832 0.625
ATF6
M04019_2.00 		Homo sapiens
KAGTCACGTGK
MCACGTGACTM		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6.2 		0.832 0.625
ATF6
M04020_2.00 		Homo sapiens
BNRTGACGTCATCA
TGATGACGTCAYNV		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6.3 		0.832 0.625
ATF6
M04021_2.00 		Homo sapiens
ACCACGATGTY
RACATCGTGGT		 SELEX
Rodriguez-Martinez et al.(2017)
ATF6.4 		0.832 0.625
ATF6
M08790_2.00 		Homo sapiens
VBSSTGACGTGG
CCACGTCASSVB		 Misc
Kulakovskiy et al.(2013)
ATF6A_HUMAN.H11MO.0.B 		0.832 0.625
ATF6
M09947_2.00 		Homo sapiens
TGACGTGG
CCACGTCA		 Transfac
Matys et al.(2006)
V$ATF6_01 		0.832 0.625
ATF6
M04256_2.00 		Homo sapiens
YGRTGACGTGGCRN
NYGCCACGTCAYCR		 SELEX
Yin et al.(2017)
ATF6_eDBD_Methyl-HT-SELEX_1 		0.832 0.625
ATF6
M04257_2.00 		Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN		 SELEX
Yin et al.(2017)
ATF6_eDBD_Methyl-HT-SELEX_2 		0.832 0.625
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000015605 bZIP 327 390
ENSMUSP00000133516 bZIP 330 393

Links

Other bZIP family TFs
Other Mus musculus TFs

Invalid Input OrderBy

112 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action