Atf7 (Mus musculus)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000099083 T060507_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; cAMP response element binding activity; and transcription coactivator binding activity. Involved in several processes, including animal organ development; hepatocyte apoptotic process; and p38MAPK cascade. Predicted to be located in nucleoplasm. Is expressed in central nervous system; early conceptus; genitourinary system; and retina. Orthologous to human ATF7 (activating transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Atf7
M01823_2.00		 Mus musculus
HKACGTMAYN
NRTKACGTMD		 PBM
Weirauch et al.(2014)
pTH5081		 (Direct) (Direct)
Atf7
M09499_2.00		 Mus musculus
NNVTGACRTCAB
VTGAYGTCABNN		 Misc
Heinz et al.(2010)
3T3L1-Atf7_GSE56872		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Creb5
M02866_2.00 		Mus musculus
NATGACGTCAYH
DRTGACGTCATN		 SELEX
Jolma et al.(2013)
Creb5_1 		0.911 0.812
ATF7
M02872_2.00 		Homo sapiens
NDRTGACGTCATNN
NNATGACGTCAYHN		 SELEX
Jolma et al.(2013)
ATF7_1 		0.989 0.989
ATF7
M04382_2.00 		Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN		 SELEX
Yin et al.(2017)
ATF7_eDBD_HT-SELEX 		0.989 0.989
CREB5
M04299_2.00 		Homo sapiens
NVTKACRTMABN
NVTKAYGTMABN		 SELEX
Yin et al.(2017)
CREB5_eDBD_HT-SELEX 		0.911 0.812
ATF7
M04383_2.00 		Homo sapiens
NRTKAYGTMATN
NATKACRTMAYN		 SELEX
Yin et al.(2017)
ATF7_eDBD_Methyl-HT-SELEX 		0.989 0.989
CREB5
M04301_2.00 		Homo sapiens
NRTKACGTMAYN
NRTKACGTMAYN		 SELEX
Yin et al.(2017)
CREB5_FL_HT-SELEX 		0.911 0.812
CREB5
M04300_2.00 		Homo sapiens
NRTKACRTCAYN
NRTGAYGTMAYN		 SELEX
Yin et al.(2017)
CREB5_eDBD_Methyl-HT-SELEX 		0.911 0.812
CREB5
M04302_2.00 		Homo sapiens
NATGACRTCAYN
NRTGAYGTCATN		 SELEX
Yin et al.(2017)
CREB5_FL_Methyl-HT-SELEX 		0.911 0.812
Atf2
M01808_2.00 		Mus musculus
NRTKAYGYMD
HKRCRTMAYN		 PBM
Weirauch et al.(2014)
pTH5083 		0.886 0.828
Atf2
M08827_2.00 		Mus musculus
VTGACVTCABY
RVTGABGTCAB		 Misc
Kulakovskiy et al.(2013)
ATF2_MOUSE.H11MO.0.A 		0.886 0.828
Atf2
M09493_2.00 		Mus musculus
NNVTGABVTCAB
VTGABVTCABNN		 Misc
Heinz et al.(2010)
3T3L1-Atf2_GSE56872 		0.886 0.828
For this family, TFs with SR scores > 0.782 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01823_2.00 bZIP 16 79

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000104456 C2H2 ZF 7 31
ENSMUSP00000104456 bZIP 330 393
ENSMUSP00000130130 C2H2 ZF 7 31
ENSMUSP00000130130 bZIP 330 393
ENSMUSP00000139054 C2H2 ZF 7 31
ENSMUSP00000139181 C2H2 ZF 7 31
ENSMUSP00000139181 bZIP 330 393
ENSMUSP00000139243 C2H2 ZF 7 31
ENSMUSP00000139243 bZIP 330 393
ENSMUSP00000139308 bZIP 330 393
ENSMUSP00000139367 C2H2 ZF 7 31

Links

Other bZIP family TFs
Other Mus musculus TFs

Invalid Input OrderBy

308 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action