CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Nfe2
(
Rattus norvegicus
)
bZIP
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00170 (bZIP_1)
IPR011616
ENSRNOG00000036837
T061331_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable several functions, including WW domain binding activity; identical protein binding activity; and protein N-terminus binding activity. Predicted to contribute to cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of bone mineralization; and negative regulation of syncytium formation by plasma membrane fusion. Predicted to be located in PML body and cytoplasm. Predicted to be part of protein-DNA complex. Predicted to be active in nucleus. Orthologous to human NFE2 (nuclear factor, erythroid 2). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Nfe2
M08843_2.00
Mus musculus
RTGACTCAGCANDW
WHNTGCTGAGTCAY
Misc
Kulakovskiy et al.(2013)
NFE2_MOUSE.H11MO.0.A
0.912
0.968
NFE2
M02832_2.00
Homo sapiens
VATGACTCATB
VATGAGTCATB
SELEX
Jolma et al.(2013)
NFE2_1
0.905
0.968
NFE2
M04266_2.00
Homo sapiens
VRTGASTCAYB
VRTGASTCAYB
SELEX
Yin et al.(2017)
NFE2_eDBD_HT-SELEX
0.905
0.968
NFE2
M04024_2.00
Homo sapiens
RTGACTCAY
RTGAGTCAY
SELEX
Rodriguez-Martinez et al.(2017)
NFE2.1
0.905
0.968
NFE2
M07813_2.00
Homo sapiens
VRTGACTCAGCANWWHB
VDWWNTGCTGAGTCAYB
ChIP-seq
Gerstein et al.(2012)
K562_NFE2_Stanford
0.905
0.968
NFE2
M08793_2.00
Homo sapiens
VVRTGACTCAGCA
TGCTGAGTCAYBB
Misc
Kulakovskiy et al.(2013)
NFE2_HUMAN.H11MO.0.A
0.905
0.968
NFE2
M09486_2.00
Homo sapiens
VATGACTCAGCA
TGCTGAGTCATB
Misc
Heinz et al.(2010)
K562-NFE2_GSE31477
0.905
0.968
NFE2
M09959_2.00
Homo sapiens
RTGASTCAGCD
HGCTGASTCAY
Transfac
Matys et al.(2006)
V$NFE2_01
0.905
0.968
NFE2
M09960_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NFE2_04
0.905
0.968
NFE2
M09961_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NFE2_Q6
0.905
0.968
NFE2
M04267_2.00
Homo sapiens
NRTGASTCAYN
NRTGASTCAYN
SELEX
Yin et al.(2017)
NFE2_eDBD_Methyl-HT-SELEX
0.905
0.968
NFE2L2
M01142_2.00
Gallus gallus
NNRTKAYNN
NNRTMAYNN
PBM
Lambert et al.(2019)
pTH9845
0.865
0.683
NFE2L2
M08789_2.00
Homo sapiens
RTGACTCAGCANWW
WWNTGCTGAGTCAY
Misc
Kulakovskiy et al.(2013)
NF2L2_HUMAN.H11MO.0.A
0.865
0.635
NFE2L2
M09943_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF2_Q3
0.865
0.635
NFE2L2
M09944_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF2_Q4_01
0.865
0.635
NFE2L2
M09945_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF2_Q4
0.865
0.635
NFE2L2
M09946_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF2_Q6
0.865
0.635
Nfe2l2
M08077_2.00
Mus musculus
NRNNRTGACTCAGCA
TGCTGAGTCAYNNYN
ChIP-seq
Mathelier et al.(2014)
MA0150.2
0.855
0.667
Nfe2l2
M08816_2.00
Mus musculus
RTGACTNAGCANDH
DHNTGCTNAGTCAY
Misc
Kulakovskiy et al.(2013)
NF2L2_MOUSE.H11MO.0.A
0.855
0.667
NFE2L1
M04008_2.00
Homo sapiens
RTGACTCAY
RTGAGTCAY
SELEX
Rodriguez-Martinez et al.(2017)
NFE2L1.1
0.829
0.587
NFE2L1
M08782_2.00
Homo sapiens
NATGAYD
HRTCATN
Misc
Kulakovskiy et al.(2013)
NF2L1_HUMAN.H11MO.0.C
0.829
0.587
Nfe2l1
M08831_2.00
Mus musculus
NATGAYD
HRTCATN
Misc
Kulakovskiy et al.(2013)
NF2L1_MOUSE.H11MO.0.C
0.829
0.587
NFE2L1
M09925_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NFE2L1_Q5
0.829
0.587
NFE2L1
M09926_2.00
Homo sapiens
NNNNHWNNATGAC
GTCATNNWDNNNN
Transfac
Matys et al.(2006)
V$TCF11_01
0.829
0.587
Nfe2l3
M10031_2.00
Mus musculus
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF3_01
0.825
0.508
NFE2L3
M09923_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NRF3_02
0.812
0.508
For this family, TFs with SR scores >
0.782
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000052156
bZIP
265
327
ALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLGSERERLLRARGEADRTLEVMRQQLT
Links
Other
bZIP
family TFs
Other
Rattus norvegicus
TFs
312 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy