CrebA (Drosophila melanogaster)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 FBgn0004396 T062072_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity and cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II; regionalization; and salivary gland development. Located in nucleus and polytene chromosome. Is expressed in several structures, including blastoderm embryo; digestive system; dorsal closure embryo; epithelium; and germ layer. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 16. Orthologous to several human genes including CREB3L1 (cAMP responsive element binding protein 3 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CrebA
M03639_2.00		 Drosophila melanogaster
TGVTGACGTGGCR
YGCCACGTCABCA		 SELEX
Nitta et al.(2015)
CrebA_1		 (Direct) (Direct)
CrebA
M03640_2.00		 Drosophila melanogaster
TGRTGACGTCAYCR
YGRTGACGTCAYCA		 SELEX
Nitta et al.(2015)
CrebA_2		 (Direct) (Direct)
CrebA
M03641_2.00		 Drosophila melanogaster
TGCCACGTGGCA
TGCCACGTGGCA		 SELEX
Nitta et al.(2015)
CrebA_3		 (Direct) (Direct)
CrebA
M06020_2.00		 Drosophila melanogaster
GNHBACGTSRCV
BGYSACGTVDNC		 B1H
Zhu et al.(2011)
CrebA_SANGER_5_FBgn0004396		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Creb3l2
M01812_2.00 		Mus musculus
HCACGTGKM
KMCACGTGD		 PBM
Weirauch et al.(2014)
pTH5024 		0.808 0.703
Creb3l2
M02863_2.00 		Mus musculus
TGRTGACGTGGCA
TGCCACGTCAYCA		 SELEX
Jolma et al.(2013)
Creb3l2_1 		0.808 0.703
Creb3l2
M02864_2.00 		Mus musculus
KGCCACGTGGCA
TGCCACGTGGCM		 SELEX
Jolma et al.(2013)
Creb3l2_2 		0.808 0.703
CREB3L2
M01143_2.00 		Monodelphis domestica
NACGTGKH
DMCACGTN		 PBM
Lambert et al.(2019)
pTH11415 		0.808 0.688
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0075311 bZIP 439 502
FBpp0089339 bZIP 439 502

Links

Other bZIP family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

187 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action