Pdp1 (Drosophila melanogaster)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 FBgn0016694 T062075_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in circadian rhythm; positive regulation of transcription, DNA-templated; and regulation of lipid metabolic process. Located in nucleus. Is expressed in several structures, including adult pacemaker neurons; extended germ band embryo; gut section; muscle system; and presumptive embryonic/larval system. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to several human genes including DBP (D-box binding PAR bZIP transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Pdp1
M03645_2.00		 Drosophila melanogaster
VTTACGTAAB
VTTACGTAAB		 SELEX
Nitta et al.(2015)
Pdp1_1		 (Direct) (Direct)
Pdp1
M03646_2.00		 Drosophila melanogaster
RTTACGTAAY
RTTACGTAAY		 SELEX
Nitta et al.(2015)
Pdp1_2		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HLF
M02831_2.00 		Homo sapiens
NRTTAYRTAABN
NVTTAYRTAAYN		 SELEX
Jolma et al.(2013)
HLF_1 		0.795 0.672
Hlf
M02860_2.00 		Mus musculus
KRTTACGTAAYN
NRTTACGTAAYM		 SELEX
Jolma et al.(2013)
Hlf_1 		0.795 0.672
HLF
M04245_2.00 		Homo sapiens
NVTTRCRYAABN
NVTTRYGYAABN		 SELEX
Yin et al.(2017)
HLF_FL_HT-SELEX 		0.795 0.672
HLF
M04016_2.00 		Homo sapiens
RTKAYRTAAB
VTTAYRTMAY		 SELEX
Rodriguez-Martinez et al.(2017)
HLF.1 		0.795 0.672
HLF
M08786_2.00 		Homo sapiens
NRTTRYGTAAYMS
SKRTTACRYAAYN		 Misc
Kulakovskiy et al.(2013)
HLF_HUMAN.H11MO.0.C 		0.795 0.672
Hlf
M08815_2.00 		Mus musculus
VTTRTGYAABH
DVTTRCAYAAB		 Misc
Kulakovskiy et al.(2013)
HLF_MOUSE.H11MO.0.C 		0.795 0.672
HLF
M09937_2.00 		Homo sapiens
ATKRYGTAAY
RTTACRYMAT		 Transfac
Matys et al.(2006)
V$HLF_01 		0.795 0.672
HLF
M04246_2.00 		Homo sapiens
NVTTRCRYAABN
NVTTRYGYAABN		 SELEX
Yin et al.(2017)
HLF_FL_Methyl-HT-SELEX 		0.795 0.672
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0076490 bZIP 182 249
FBpp0076491 bZIP 202 269
FBpp0076492 bZIP 216 283
FBpp0076495 bZIP 579 643
FBpp0076497 bZIP 502 567
FBpp0289726 bZIP 163 227
FBpp0289727 bZIP 565 629
FBpp0297493 bZIP 202 269
FBpp0304390 bZIP 513 578
FBpp0304391 bZIP 207 274
FBpp0304392 bZIP 213 280
FBpp0304393 bZIP 196 263
FBpp0312154 bZIP 202 269

Links

Other bZIP family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

132 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action