CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Atf6
(
Drosophila melanogaster
)
bZIP
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00170 (bZIP_1)
IPR011616
FBgn0033010
T062079_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in endoplasmic reticulum unfolded protein response and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in germline cell; organism; pole plasm; and primordial germ cell. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6) and ATF6B (activating transcription factor 6 beta). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Atf6
M03650_2.00
Drosophila melanogaster
DYGRTGACGTGKCAN
NTGMCACGTCAYCRH
SELEX
Nitta et al.(2015)
CG3136_1
(Direct)
(Direct)
Atf6
M03651_2.00
Drosophila melanogaster
NTGATGACGTCAY
RTGACGTCATCAN
SELEX
Nitta et al.(2015)
CG3136_2
(Direct)
(Direct)
Atf6
M03652_2.00
Drosophila melanogaster
TGMCACGTGKCA
TGMCACGTGKCA
SELEX
Nitta et al.(2015)
CG3136_3
(Direct)
(Direct)
Atf6
M06024_2.00
Drosophila melanogaster
GSTGACGTGKMA
TKYCACGTCASC
B1H
Zhu et al.(2011)
Atf6_SANGER_5_FBgn0033010
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.782
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
FBpp0085415
bZIP
280
341
DKIYKKYQRMIKNRESASLSRKKRKEYVVSLETRINKLEKECDSLKAENITLRDQIFLLATS
FBpp0085416
bZIP
280
341
DKIYKKYQRMIKNRESASLSRKKRKEYVVSLETRINKLEKECDSLKAENITLRDQIFLLATS
FBpp0085417
bZIP
282
343
DKIYKKYQRMIKNRESASLSRKKRKEYVVSLETRINKLEKECDSLKAENITLRDQIFLLATS
Links
Other
bZIP
family TFs
Other
Drosophila melanogaster
TFs
5 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
GM26735
Drosophila sechellia
FBgn0181588
I
0.841
GE11351
Drosophila yakuba
FBgn0229164
I
0.801
GG23144
Drosophila erecta
FBgn0115296
I
0.800
MDOA012880
Musca domestica
MDOA012880
I
0.784