Atf6 (Drosophila melanogaster)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 FBgn0033010 T062079_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in endoplasmic reticulum unfolded protein response and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in germline cell; organism; pole plasm; and primordial germ cell. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6) and ATF6B (activating transcription factor 6 beta). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Atf6
M03650_2.00		 Drosophila melanogaster
DYGRTGACGTGKCAN
NTGMCACGTCAYCRH		 SELEX
Nitta et al.(2015)
CG3136_1		 (Direct) (Direct)
Atf6
M03651_2.00		 Drosophila melanogaster
NTGATGACGTCAY
RTGACGTCATCAN		 SELEX
Nitta et al.(2015)
CG3136_2		 (Direct) (Direct)
Atf6
M03652_2.00		 Drosophila melanogaster
TGMCACGTGKCA
TGMCACGTGKCA		 SELEX
Nitta et al.(2015)
CG3136_3		 (Direct) (Direct)
Atf6
M06024_2.00		 Drosophila melanogaster
GSTGACGTGKMA
TKYCACGTCASC		 B1H
Zhu et al.(2011)
Atf6_SANGER_5_FBgn0033010		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0085415 bZIP 280 341
FBpp0085416 bZIP 280 341
FBpp0085417 bZIP 282 343

Links

Other bZIP family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

5 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action