Atf-2 (Drosophila melanogaster)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 FBgn0265193 T062297_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in several processes, including cellular response to heat; regulation of cellular biosynthetic process; and stress-activated MAPK cascade. Located in chromocenter; nucleus; and pericentric heterochromatin. Is expressed in organism. Orthologous to several human genes including ATF2 (activating transcription factor 2); ATF7 (activating transcription factor 7); and CREB5 (cAMP responsive element binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Atf-2
M03657_2.00		 Drosophila melanogaster
NNRTSACGTSAYNN
NNRTSACGTSAYNN		 SELEX
Nitta et al.(2015)
CG30420_1		 (Direct) (Direct)
Atf-2
M03658_2.00		 Drosophila melanogaster
NRATGACGTCATYN
NRATGACGTCATYN		 SELEX
Nitta et al.(2015)
CG30420_2		 (Direct) (Direct)
Atf-2
M06027_2.00		 Drosophila melanogaster
KATGACGTSAY
RTSACGTCATM		 B1H
Zhu et al.(2011)
Atf-2_SANGER_5_FBgn0050420		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0308241 bZIP 280 342

Links

Other bZIP family TFs
Other Drosophila melanogaster TFs

8 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
GD11905 Drosophila simulans FBgn0183644 I 0.951
GM11907 Drosophila sechellia FBgn0166848 I 0.951
GE14449 Drosophila yakuba FBgn0232055 I 0.938
GG23012 Drosophila erecta FBgn0115169 I 0.925
GK21677 Drosophila willistoni FBgn0223662 I 0.867
GA24876 Drosophila pseudoobscura FBgn0246261 I 0.828
GL17691 Drosophila persimilis FBgn0155294 I 0.824
GF13345 Drosophila ananassae FBgn0090377 I 0.816