jun-1 (Caenorhabditis elegans)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 WBGene00012005 T069406_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of RNA splicing; and response to starvation. Located in nucleus. Is expressed in several structures, including excretory cell; hermaphrodite gonad; intestine; nervous system; and pharyngeal-intestinal valve. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); JUNB (JunB proto-oncogene, AP-1 transcription factor subunit); and JUND (JunD proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
jun-1
M00599_2.00		 Caenorhabditis elegans
RTGACTCAN
NTGAGTCAY		 PBM
Narasimhan et al.(2015)
pTH9928		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.782 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00599_2.00 bZIP 51 114

DNA Binding Domains

Protein ID Domain From To Sequence
T24H10.7a bZIP 242 305
T24H10.7b bZIP 222 285
T24H10.7c bZIP 24 87
T24H10.7d bZIP 78 141
T24H10.7e bZIP 87 150

Links

Other bZIP family TFs
Other Caenorhabditis elegans TFs

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5 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action