crh-2 (Caenorhabditis elegans)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 WBGene00016162 T069412_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cAMP response element binding activity. Involved in defense response to Gram-negative bacterium; positive regulation of dauer entry; and regulation of gene expression. Is expressed in several structures, including hypodermis; intestine; nervous system; pharynx; and spermatheca. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 16. Orthologous to several human genes including CREB3L1 (cAMP responsive element binding protein 3 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
crh-2
M00603_2.00		 Caenorhabditis elegans
NBACGTGGMN
NKCCACGTVN		 PBM
Narasimhan et al.(2015)
pTH9879		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.782 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00603_2.00 bZIP 51 117

DNA Binding Domains

Protein ID Domain From To Sequence
C27D6.4a bZIP 153 220
C27D6.4b bZIP 258 323
C27D6.4c bZIP 280 344
C27D6.4d bZIP 148 214

Links

Other bZIP family TFs
Other Caenorhabditis elegans TFs

Invalid Input OrderBy

5 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action