MYT1L (Homo sapiens)
C2HC ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01530 (zf-C2HC) IPR002515 ENSG00000186487 T070062_1.02 Ensembl (2011-Oct-26) Link out
NCBI Gene Info:
This gene encodes a member of the zinc finger superfamily of transcription factors whose expression, thus far, has been found only in neuronal tissues. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with an autosomal dominant form of cognitive disability and with autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Jul 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000295067 C2HC ZF 28 58
ENSP00000295067 C2HC ZF 449 479
ENSP00000295067 C2HC ZF 493 523
ENSP00000295067 C2HC ZF 848 878
ENSP00000295067 C2HC ZF 897 927
ENSP00000295067 C2HC ZF 950 980
ENSP00000382111 C2HC ZF 5 35
ENSP00000382111 C2HC ZF 58 88
ENSP00000382114 C2HC ZF 28 58
ENSP00000382114 C2HC ZF 503 533
ENSP00000382114 C2HC ZF 547 577
ENSP00000382114 C2HC ZF 902 932
ENSP00000382114 C2HC ZF 951 981
ENSP00000382114 C2HC ZF 1004 1034
ENSP00000384219 C2HC ZF 1 30
ENSP00000394172 C2HC ZF 1 30
ENSP00000396103 C2HC ZF 28 58
ENSP00000396103 C2HC ZF 501 531
ENSP00000396103 C2HC ZF 545 575
ENSP00000396103 C2HC ZF 900 930
ENSP00000396103 C2HC ZF 949 979
ENSP00000396103 C2HC ZF 1002 1032

Links

Other C2HC ZF family TFs
Other Homo sapiens TFs

0 Related TFs

">No related TF found