|
ENSBTAP00000007199-D1
(Bos grunniens)
bZIP
|
TF Information |
Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
PF00170 (bZIP_1) |
IPR011616 |
ENSBTAP00000007199-D1 |
T070112_2.00 |
GigaDB (2015-Oct-22) |
NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
No direct experiments |
|
|
|
|
|
Motifs from related TFs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
Creb1
M00992_2.00 |
Mus musculus |
NNTGACGTCV |
BGACGTCANN |
PBM
Mann et al.(2013)
CREB1_UM_HK
|
0.904
|
1.000
|
Creb1
M01806_2.00 |
Mus musculus |
VTKACGHNN |
NNDCGTMAB |
PBM
Weirauch et al.(2014)
pTH5080
|
0.904
|
1.000
|
CREB1
M04264_2.00 |
Homo sapiens |
NVTKACGTMABN |
NVTKACGTMABN |
SELEX
Yin et al.(2017)
CREB1_FL_HT-SELEX
|
0.904
|
1.000
|
CREB1
M04258_2.00 |
Homo sapiens |
NVTKACGTMANN |
NNTKACGTMABN |
SELEX
Yin et al.(2017)
CREB1_eDBD_HT-SELEX_1
|
0.904
|
1.000
|
CREB1
M04259_2.00 |
Homo sapiens |
NRTGACGTR |
YACGTCAYN |
SELEX
Yin et al.(2017)
CREB1_eDBD_HT-SELEX_2
|
0.904
|
1.000
|
CREB1
M04260_2.00 |
Homo sapiens |
VTSACRYGWBAY |
RTVWCRYGTSAB |
SELEX
Yin et al.(2017)
CREB1_eDBD_HT-SELEX_3
|
0.904
|
1.000
|
CREB1
M04022_2.00 |
Homo sapiens |
NRTGACGTCAYN |
NRTGACGTCAYN |
SELEX
Rodriguez-Martinez et al.(2017)
CREB1.1
|
0.904
|
1.000
|
CREB1
M04023_2.00 |
Homo sapiens |
RTGACGTADB |
VHTACGTCAY |
SELEX
Rodriguez-Martinez et al.(2017)
CREB1.2
|
0.904
|
1.000
|
CREB1
M08066_2.00 |
Homo sapiens |
NVTGACGTCABN |
NVTGACGTCABN |
ChIP-seq
Mathelier et al.(2014)
MA0018.3
|
0.904
|
1.000
|
CREB1
M08791_2.00 |
Homo sapiens |
WKRCGTCAYYN |
NRRTGACGYMW |
Misc
Kulakovskiy et al.(2013)
CREB1_HUMAN.H11MO.0.A
|
0.904
|
1.000
|
Creb1
M08824_2.00 |
Mus musculus |
WKRCGTCAYYN |
NRRTGACGYMW |
Misc
Kulakovskiy et al.(2013)
CREB1_MOUSE.H11MO.0.A
|
0.904
|
1.000
|
CREB1
M09948_2.00 |
Homo sapiens |
TGACGTMW |
WKACGTCA |
Transfac
Matys et al.(2006)
V$CREB_01
|
0.904
|
1.000
|
CREB1
M09949_2.00 |
Homo sapiens |
BBGDTGACGYVV |
BBRCGTCAHCVV |
Transfac
Matys et al.(2006)
V$CREB_02
|
0.904
|
1.000
|
CREB1
M09950_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$CREB1_Q3
|
0.904
|
1.000
|
CREB1
M09951_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$CREB1_Q6
|
0.904
|
1.000
|
CREB1
M09952_2.00 |
Homo sapiens |
BSTGACGYARNN |
NNYTRCGTCASV |
Transfac
Matys et al.(2006)
V$CREB_Q2
|
0.904
|
1.000
|
CREB1
M09953_2.00 |
Homo sapiens |
BSTGACGYMRBV |
BVYKRCGTCASV |
Transfac
Matys et al.(2006)
V$CREB_Q4
|
0.904
|
1.000
|
CREB1
M09954_2.00 |
Homo sapiens |
KKGGGKTGACGYMND |
HNKRCGTCAMCCCMM |
Transfac
Matys et al.(2006)
V$TAXCREB_01
|
0.904
|
1.000
|
CREB1
M09955_2.00 |
Homo sapiens |
RTGACGCATAYCCCC |
GGGGRTATGCGTCAY |
Transfac
Matys et al.(2006)
V$TAXCREB_02
|
0.904
|
1.000
|
Creb1
M00991_2.00 |
Mus musculus |
NNRTGACGYVN |
NBRCGTCAYNN |
PBM
Mann et al.(2013)
CREB1_M_HK
|
0.904
|
1.000
|
CREB1
M04265_2.00 |
Homo sapiens |
NRTGACRTCAYN |
NRTGAYGTCAYN |
SELEX
Yin et al.(2017)
CREB1_FL_Methyl-HT-SELEX
|
0.904
|
1.000
|
CREB1
M04261_2.00 |
Homo sapiens |
BRTGAYGYGND |
HNCRCRTCAYV |
SELEX
Yin et al.(2017)
CREB1_eDBD_Methyl-HT-SELEX_1
|
0.904
|
1.000
|
CREB1
M04262_2.00 |
Homo sapiens |
NRTGACRTCAYN |
NRTGAYGTCAYN |
SELEX
Yin et al.(2017)
CREB1_eDBD_Methyl-HT-SELEX_2
|
0.904
|
1.000
|
CREB1
M04263_2.00 |
Homo sapiens |
NRTGACGYV |
BRCGTCAYN |
SELEX
Yin et al.(2017)
CREB1_eDBD_Methyl-HT-SELEX_3
|
0.904
|
1.000
|
ATF1
M08792_2.00 |
Homo sapiens |
HBRCGTCAYHN |
NDRTGACGYVD |
Misc
Kulakovskiy et al.(2013)
ATF1_HUMAN.H11MO.0.B
|
0.894
|
0.867
|
ATF1
M09485_2.00 |
Homo sapiens |
NVTGACGTMA |
TKACGTCABN |
Misc
Heinz et al.(2010)
K562-ATF1_GSE31477
|
0.894
|
0.867
|
ATF1
M09956_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$ATF1_Q3
|
0.894
|
0.867
|
ATF1
M09957_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$ATF1_Q6_01
|
0.894
|
0.867
|
ATF1
M09958_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$ATF1_Q6
|
0.894
|
0.867
|
Atf1
M00124_2.00 |
Mus musculus |
NNNNDNDNNN |
NNNHNHNNNN |
PBM
Badis et al.(2009)
Atf1_3026
|
0.883
|
0.867
|
Atf1
M01804_2.00 |
Mus musculus |
RTGACGTV |
BACGTCAY |
PBM
Weirauch et al.(2014)
pTH5005
|
0.883
|
0.867
|
Atf1
M08820_2.00 |
Mus musculus |
VTGACGTSAV |
BTSACGTCAB |
Misc
Kulakovskiy et al.(2013)
ATF1_MOUSE.H11MO.0.B
|
0.883
|
0.867
|
Crem
M01821_2.00 |
Mus musculus |
NRTKACGTMN |
NKACGTMAYN |
PBM
Weirauch et al.(2014)
pTH5002
|
0.882
|
0.950
|
Crem
M08845_2.00 |
Mus musculus |
SVVTGACGTSA |
TSACGTCABBS |
Misc
Kulakovskiy et al.(2013)
CREM_MOUSE.H11MO.0.C
|
0.882
|
0.950
|
CREM
M04229_2.00 |
Homo sapiens |
VVTBACGTVABN |
NVTBACGTVABB |
SELEX
Yin et al.(2017)
CREM_eDBD_HT-SELEX
|
0.851
|
0.767
|
CREM
M08784_2.00 |
Homo sapiens |
SVVTGACGTSA |
TSACGTCABBS |
Misc
Kulakovskiy et al.(2013)
CREM_HUMAN.H11MO.0.C
|
0.851
|
0.767
|
CREM
M09930_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$CREM_Q6_01
|
0.851
|
0.767
|
CREM
M09931_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$CREM_Q6
|
0.851
|
0.767
|
CREM
M04230_2.00 |
Homo sapiens |
NRTGACRTCAYN |
NRTGAYGTCAYN |
SELEX
Yin et al.(2017)
CREM_eDBD_Methyl-HT-SELEX
|
0.851
|
0.767
|
CrebB-17A
M03659_2.00 |
Drosophila melanogaster |
RTGACGTCAY |
RTGACGTCAY |
SELEX
Nitta et al.(2015)
CrebB-17A_1
|
0.819
|
0.800
|
CrebB-17A
M03660_2.00 |
Drosophila melanogaster |
RTGACGTCAY |
RTGACGTCAY |
SELEX
Nitta et al.(2015)
CrebB-17A_2
|
0.819
|
0.800
|
For this family, TFs with SR scores > 0.782 will likely have a similar motif |