ENSP00000226067 (Macaca fascicularis)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00170 (bZIP_1) IPR011616 ENSP00000226067 T070145_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
HLF
M02831_2.00
Homo sapiens
NRTTAYRTAABN

NVTTAYRTAAYN
SELEX
Jolma et al.(2013)
HLF_1
0.896 1.000
Hlf
M02860_2.00
Mus musculus
KRTTACGTAAYN

NRTTACGTAAYM
SELEX
Jolma et al.(2013)
Hlf_1
0.896 1.000
HLF
M04245_2.00
Homo sapiens
NVTTRCRYAABN

NVTTRYGYAABN
SELEX
Yin et al.(2017)
HLF_FL_HT-SELEX
0.896 1.000
HLF
M04016_2.00
Homo sapiens
RTKAYRTAAB

VTTAYRTMAY
SELEX
Rodriguez-Martinez et al.(2017)
HLF.1
0.896 1.000
HLF
M08786_2.00
Homo sapiens
NRTTRYGTAAYMS

SKRTTACRYAAYN
Misc
Kulakovskiy et al.(2013)
HLF_HUMAN.H11MO.0.C
0.896 1.000
Hlf
M08815_2.00
Mus musculus
VTTRTGYAABH

DVTTRCAYAAB
Misc
Kulakovskiy et al.(2013)
HLF_MOUSE.H11MO.0.C
0.896 1.000
HLF
M09937_2.00
Homo sapiens
ATKRYGTAAY

RTTACRYMAT
Transfac
Matys et al.(2006)
V$HLF_01
0.896 1.000
HLF
M04246_2.00
Homo sapiens
NVTTRCRYAABN

NVTTRYGYAABN
SELEX
Yin et al.(2017)
HLF_FL_Methyl-HT-SELEX
0.896 1.000
Tef
M01803_2.00
Mus musculus
NVTTRYVNNN

NNNBRYAABN
PBM
Weirauch et al.(2014)
pTH5078
0.847 0.794
TEF
M02849_2.00
Homo sapiens
NRTTAYGTAAYN

NRTTACRTAAYN
SELEX
Jolma et al.(2013)
TEF_1
0.847 0.794
TEF
M02850_2.00
Homo sapiens
NVTTAYGTAABN

NVTTACRTAABN
SELEX
Jolma et al.(2013)
TEF_2
0.847 0.794
TEF
M04325_2.00
Homo sapiens
NRTTACGTAAYN

NRTTACGTAAYN
SELEX
Yin et al.(2017)
TEF_eDBD_HT-SELEX
0.847 0.794
TEF
M09983_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TEF_05
0.847 0.794
TEF
M09984_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TEF_06
0.847 0.794
TEF
M09985_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TEF_Q6
0.847 0.794
TEF
M09986_2.00
Homo sapiens
MTKAYGTAAY

RTTACRTMAK
Transfac
Matys et al.(2006)
V$VBP_01
0.847 0.794
TEF
M04326_2.00
Homo sapiens
NRTTACRTAAYN

NRTTAYGTAAYN
SELEX
Yin et al.(2017)
TEF_eDBD_Methyl-HT-SELEX
0.847 0.794
Pdp1
M03645_2.00
Drosophila melanogaster
VTTACGTAAB

VTTACGTAAB
SELEX
Nitta et al.(2015)
Pdp1_1
0.795 0.683
Pdp1
M03646_2.00
Drosophila melanogaster
RTTACGTAAY

RTTACGTAAY
SELEX
Nitta et al.(2015)
Pdp1_2
0.795 0.683
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000226067 bZIP 186 248

Links

Other bZIP family TFs
Other Macaca fascicularis TFs

232 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ACYPI000702 Acyrthosiphon pisum ACYPI000702 I 0.783
PDP1 Aedes aegypti AAEL005255 I 0.822
ENSAMEG00000002146 Ailuropoda melanoleuca ENSAMEG00000002146 I 0.847
ENSAMEG00000014714 Ailuropoda melanoleuca ENSAMEG00000014714 I 0.896
Alligator_sinensis_CCG018001.1 Alligator sinensis Alligator_sinensis_CCG018001.1 I 0.788
Alligator_sinensis_CCG007983.1 Alligator sinensis Alligator_sinensis_CCG007983.1 I 0.847
Alligator_sinensis_CCG020587.1 Alligator sinensis Alligator_sinensis_CCG020587.1 I 0.881
ENSAPLG00000005838 Anas platyrhynchos ENSAPLG00000005838 I 0.847
ENSAPLG00000004386 Anas platyrhynchos ENSAPLG00000004386 I 0.893
DBP Anolis carolinensis ENSACAG00000015667 I 0.788
TEF Anolis carolinensis ENSACAG00000004810 I 0.847
HLF Anolis carolinensis ENSACAG00000017417 I 0.893
AALB004300 Anopheles albimanus AALB004300 I 0.822
AARA000887 Anopheles arabiensis AARA000887 I 0.822
AATE006511 Anopheles atroparvus AATE006511 I 0.845
ACOM039838 Anopheles coluzzii ACOM039838 I 0.822
ACUA004794 Anopheles culicifacies ACUA004794 I 0.822
ADAC004162 Anopheles darlingi ADAC004162 I 0.822
ADIR007438 Anopheles dirus ADIR007438 I 0.822
AEPI005427 Anopheles epiroticus AEPI005427 I 0.822
AFAF017409 Anopheles farauti AFAF017409 I 0.822
AFUN000141 Anopheles funestus AFUN000141 I 0.822
PDP1 Anopheles gambiae AGAP006376 I 0.822
AMEM018156 Anopheles merus AMEM018156 I 0.822
AMIN007990 Anopheles minimus AMIN007990 I 0.822
AQUA000938 Anopheles quadriannulatus AQUA000938 I 0.822
ASIS001542 Anopheles sinensis ASIS001542 I 0.822
ASTEI09431 Anopheles stephensi ASTEI09431 I 0.822
GB43643 Apis mellifera GB43643 I 0.829
Afo_R002997 Aptenodytes forsteri Afo_R002997 I 0.893
Afo_R007951 Aptenodytes forsteri Afo_R007951 I 0.847
ENSAMXG00000009417 Astyanax mexicanus ENSAMXG00000009417 I 0.791
ENSAMXG00000016053 Astyanax mexicanus ENSAMXG00000016053 I 0.812
ENSAMXG00000008798 Astyanax mexicanus ENSAMXG00000008798 I 0.842
ENSAMXG00000015442 Astyanax mexicanus ENSAMXG00000015442 I 0.841
ENSAMXG00000017639 Astyanax mexicanus ENSAMXG00000017639 I 0.867
ACEP27179 Atta cephalotes ACEP27179 I 0.829
BGIBMGA003874 Bombyx mori BGIBMGA003874 I 0.832
ENSBTAP00000022056-D1 Bos grunniens ENSBTAP00000022056-D1 I 0.847
ENSBTAP00000008682-D1 Bos grunniens ENSBTAP00000008682-D1 I 0.896
HLF Bos taurus ENSBTAG00000006618 I 0.896
TEF Bos taurus ENSBTAG00000016580 I 0.847
e_gw.24.282.1 Branchiostoma floridae e_gw.24.282.1 I 0.803
Brh_R010854 Buceros rhinoceros Brh_R010854 I 0.847
Brh_R008067 Buceros rhinoceros Brh_R008067 I 0.893
TEF Callithrix jacchus ENSCJAG00000004977 I 0.847
HLF Callithrix jacchus ENSCJAG00000011298 I 0.896
Aan_R004902 Calypte anna Aan_R004902 I 0.893
Aan_R013230 Calypte anna Aan_R013230 I 0.847
Cflo_03674--XP_391997.2_APIME Camponotus floridanus Cflo_03674--XP_391997.2_APIME I 0.829
TEF Canis familiaris ENSCAFG00000001095 I 0.847
HLF Canis familiaris ENSCAFG00000030851 I 0.896
ENSCPOG00000011000 Cavia porcellus ENSCPOG00000011000 I 0.896
TEF Cavia porcellus ENSCPOG00000020591 I 0.847
Cmyd_10013489 Chelonia mydas Cmyd_10013489 I 0.893
ENSCSAG00000005557 Chlorocebus sabaeus ENSCSAG00000005557 I 0.896
ENSCSAG00000005816 Chlorocebus sabaeus ENSCSAG00000005816 I 0.847
ENSCHOG00000001396 Choloepus hoffmanni ENSCHOG00000001396 I 0.896
TEF Choloepus hoffmanni ENSCHOG00000009442 I 0.806
CLEC008918 Cimex lectularius CLEC008918 I 0.782
CGI_10008414 Crassostrea gigas CGI_10008414 I 0.782
CpipJ_CPIJ014920 Culex pipiens CpipJ_CPIJ014920 I 0.822
PDP1 Culex quinquefasciatus CPIJ014920 I 0.822
KGM_21614 Danaus plexippus KGM_21614 I 0.832
tefb Danio rerio ENSDARG00000098103 I 0.831
hlfa Danio rerio ENSDARG00000074752 I 0.865
dbpa Danio rerio ENSDARG00000063014 I 0.798
tefa Danio rerio ENSDARG00000039117 I 0.831
hlfb Danio rerio ENSDARG00000061011 I 0.842
DAPPUDRAFT_102458 Daphnia pulex DAPPUDRAFT_102458 I 0.794
TEF Dasypus novemcinctus ENSDNOG00000035257 I 0.847
YQE_01842 Dendroctonus ponderosae YQE_01842 I 0.815
ENSDORG00000012644 Dipodomys ordii ENSDORG00000012644 I 0.896
Tef Dipodomys ordii ENSDORG00000014982 I 0.847
GF24150 Drosophila ananassae FBgn0101144 I 0.795
GG14935 Drosophila erecta FBgn0107189 I 0.795
GH23565 Drosophila grimshawi FBgn0131022 I 0.795
Pdp1 Drosophila melanogaster FBgn0016694 D 0.795
GI12193 Drosophila mojavensis FBgn0134950 I 0.795
GL17823 Drosophila persimilis FBgn0155426 I 0.795
GA28498 Drosophila pseudoobscura FBgn0249858 I 0.795
GM24985 Drosophila sechellia FBgn0179846 I 0.795
GD13032 Drosophila simulans FBgn0184754 I 0.795
GJ11425 Drosophila virilis FBgn0198683 I 0.795
GK10510 Drosophila willistoni FBgn0212525 I 0.795
GE20386 Drosophila yakuba FBgn0237702 I 0.795
HLF Echinops telfairi ENSETEG00000017670 I 0.896
TEF Equus caballus ENSECAG00000018137 I 0.847
HLF Equus caballus ENSECAG00000016953 I 0.896
HLF Erinaceus europaeus ENSEEUG00000010964 I 0.896
TEF Felis catus ENSFCAG00000003674 I 0.847
HLF Felis catus ENSFCAG00000022556 I 0.896
ENSFALG00000002265 Ficedula albicollis ENSFALG00000002265 I 0.893
ENSFALG00000011967 Ficedula albicollis ENSFALG00000011967 I 0.847
ENSGMOG00000014488 Gadus morhua ENSGMOG00000014488 I 0.802
ENSGMOG00000013327 Gadus morhua ENSGMOG00000013327 I 0.794
ENSGMOG00000004830 Gadus morhua ENSGMOG00000004830 I 0.863
TEF Gallus gallus ENSGALG00000011958 I 0.847
HLF Gallus gallus ENSGALG00000003059 I 0.893
tefb Gasterosteus aculeatus ENSGACG00000007628 I 0.858
tefa Gasterosteus aculeatus ENSGACG00000004793 I 0.822
hlfb Gasterosteus aculeatus ENSGACG00000010103 I 0.826
Gfo_R004744 Geospiza fortis Gfo_R004744 I 0.847
Gfo_R006518 Geospiza fortis Gfo_R006518 I 0.893
TEF Gorilla gorilla ENSGGOG00000016460 I 0.847
HLF Gorilla gorilla ENSGGOG00000006075 I 0.896
HHAL005759-PA Halyomorpha halys HHAL005759-PA I 0.786
Hsal_12188--XP_391997.2_APIME Harpegnathos saltator Hsal_12188--XP_391997.2_APIME I 0.829
HMEL011029 Heliconius melpomene HMEL011029 I 0.832
HLF Homo sapiens ENSG00000108924 D 0.896
TEF Homo sapiens ENSG00000167074 D 0.847
ENSSTOG00000029018 Ictidomys tridecemlineatus ENSSTOG00000029018 I 0.896
ENSSTOG00000019642 Ictidomys tridecemlineatus ENSSTOG00000019642 I 0.847
ISCW004978 Ixodes scapularis ISCW004978 I 0.793
ENSLACG00000006062 Latimeria chalumnae ENSLACG00000006062 I 0.784
ENSLACG00000012726 Latimeria chalumnae ENSLACG00000012726 I 0.893
ENSLACG00000012701 Latimeria chalumnae ENSLACG00000012701 I 0.870
ENSLOCG00000011595 Lepisosteus oculatus ENSLOCG00000011595 I 0.849
ENSLOCG00000012233 Lepisosteus oculatus ENSLOCG00000012233 I 0.896
TEF Loxodonta africana ENSLAFG00000013151 I 0.847
HLF Loxodonta africana ENSLAFG00000016475 I 0.896
LCUP014933 Lucilia cuprina LCUP014933 I 0.795
LLOJ006612 Lutzomyia longipalpis LLOJ006612 I 0.798
ENSP00000403078 Macaca fascicularis ENSP00000403078 I 0.847
TEF Macaca mulatta ENSMMUG00000005221 I 0.847
HLF Macaca mulatta ENSMMUG00000022627 I 0.896
ENSMEUG00000013604 Macropus eugenii ENSMEUG00000013604 I 0.847
ENSMEUG00000016384 Macropus eugenii ENSMEUG00000016384 I 0.896
TEF Meleagris gallopavo ENSMGAG00000012262 I 0.847
MCINX004280 Melitaea cinxia MCINX004280 I 0.832
ENSMICG00000002860 Microcebus murinus ENSMICG00000002860 I 0.896
ENSMICG00000013518 Microcebus murinus ENSMICG00000013518 I 0.847
TEF Monodelphis domestica ENSMODG00000016547 I 0.847
HLF Monodelphis domestica ENSMODG00000014851 I 0.896
MDOA003519 Musca domestica MDOA003519 I 0.795
ENSMPUG00000015400 Mustela putorius furo ENSMPUG00000015400 I 0.896
ENSMPUG00000016407 Mustela putorius furo ENSMPUG00000016407 I 0.847
Tef Mus musculus ENSMUSG00000022389 D 0.847
Hlf Mus musculus ENSMUSG00000003949 D 0.896
Myotis_brandtii_Tef_10013968 Myotis brandtii Myotis_brandtii_Tef_10013968 I 0.847
Myotis_brandtii_Hlf_10020713 Myotis brandtii Myotis_brandtii_Hlf_10020713 I 0.896
TEF Myotis lucifugus ENSMLUG00000002459 I 0.847
HLF Myotis lucifugus ENSMLUG00000007393 I 0.896
NV13265 Nasonia vitripennis NV13265 I 0.829
ENSNLEG00000015473 Nomascus leucogenys ENSNLEG00000015473 I 0.847
ENSNLEG00000007993 Nomascus leucogenys ENSNLEG00000007993 I 0.896
TEF Ochotona princeps ENSOPRG00000013592 I 0.846
HLF Ochotona princeps ENSOPRG00000004195 I 0.896
Ogr14443 Ophisaurus gracilis Ogr14443 I 0.847
Ogr12886 Ophisaurus gracilis Ogr12886 I 0.788
Ogr00037 Ophisaurus gracilis Ogr00037 I 0.876
ENSONIG00000012778 Oreochromis niloticus ENSONIG00000012778 I 0.819
ENSONIG00000019079 Oreochromis niloticus ENSONIG00000019079 I 0.883
ENSONIG00000009563 Oreochromis niloticus ENSONIG00000009563 I 0.879
ENSONIG00000019694 Oreochromis niloticus ENSONIG00000019694 I 0.859
ENSONIG00000007041 Oreochromis niloticus ENSONIG00000007041 I 0.791
ENSONIG00000008480 Oreochromis niloticus ENSONIG00000008480 I 0.859
TEF Ornithorhynchus anatinus ENSOANG00000011535 I 0.847
HLF Ornithorhynchus anatinus ENSOANG00000010288 I 0.881
TEF Oryctolagus cuniculus ENSOCUG00000012866 I 0.847
HLF Oryctolagus cuniculus ENSOCUG00000010547 I 0.896
hlfa Oryzias latipes ENSORLG00000000969 I 0.879
tefb Oryzias latipes ENSORLG00000014144 I 0.862
ENSORLG00000011412 Oryzias latipes ENSORLG00000011412 I 0.819
tefa Oryzias latipes ENSORLG00000002582 I 0.843
TEF Otolemur garnettii ENSOGAG00000025997 I 0.847
HLF Otolemur garnettii ENSOGAG00000007056 I 0.896
ENSOARG00000018238 Ovis aries ENSOARG00000018238 I 0.847
HLF Pan troglodytes ENSPTRG00000009424 I 0.896
TEF Pan troglodytes ENSPTRG00000014425 I 0.847
ENSPANG00000022360 Papio anubis ENSPANG00000022360 I 0.896
ENSPANG00000024579 Papio anubis ENSPANG00000024579 I 0.847
PHUM426270 Pediculus humanus PHUM426270 I 0.795
ENSPSIG00000016356 Pelodiscus sinensis ENSPSIG00000016356 I 0.893
ENSPSIG00000006835 Pelodiscus sinensis ENSPSIG00000006835 I 0.847
PPAI002842 Phlebotomus papatasi PPAI002842 I 0.798
ENSPFOG00000018222 Poecilia formosa ENSPFOG00000018222 I 0.879
ENSPFOG00000004560 Poecilia formosa ENSPFOG00000004560 I 0.896
ENSPFOG00000007430 Poecilia formosa ENSPFOG00000007430 I 0.798
ENSPFOG00000010189 Poecilia formosa ENSPFOG00000010189 I 0.806
ENSPFOG00000013950 Poecilia formosa ENSPFOG00000013950 I 0.862
ENSPFOG00000016821 Poecilia formosa ENSPFOG00000016821 I 0.860
Pvit_18616 Pogona vitticeps Pvit_18616 I 0.847
Pvit_12136 Pogona vitticeps Pvit_12136 I 0.788
Pvit_00680 Pogona vitticeps Pvit_00680 I 0.893
ENSPPYG00000008257 Pongo abelii ENSPPYG00000008257 I 0.896
ENSPPYG00000011867 Pongo abelii ENSPPYG00000011867 I 0.847
HLF Pteropus vampyrus ENSPVAG00000007461 I 0.896
TEF Pteropus vampyrus ENSPVAG00000001160 I 0.847
Tef Rattus norvegicus ENSRNOG00000019383 I 0.847
Hlf Rattus norvegicus ENSRNOG00000002456 I 0.896
ENSSHAG00000009361 Sarcophilus harrisii ENSSHAG00000009361 I 0.847
ENSSHAG00000015304 Sarcophilus harrisii ENSSHAG00000015304 I 0.896
TEF Sorex araneus ENSSARG00000003323 I 0.847
ENSSARG00000013841 Sorex araneus ENSSARG00000013841 I 0.896
SMAR002779 Strigamia maritima SMAR002779 I 0.818
SPU_004414 Strongylocentrotus purpuratus SPU_004414 I 0.830
TEF Taeniopygia guttata ENSTGUG00000009944 I 0.847
HLF Taeniopygia guttata ENSTGUG00000009478 I 0.893
ENSTRUG00000007098 Takifugu rubripes ENSTRUG00000007098 I 0.805
hlfa Takifugu rubripes ENSTRUG00000003731 I 0.842
ENSTRUG00000003893 Takifugu rubripes ENSTRUG00000003893 I 0.819
tefb Takifugu rubripes ENSTRUG00000003565 I 0.858
hlfb Takifugu rubripes ENSTRUG00000003909 I 0.868
tefa Takifugu rubripes ENSTRUG00000017028 I 0.860
ENSTSYG00000008965 Tarsius syrichta ENSTSYG00000008965 I 0.847
ENSTSYG00000009210 Tarsius syrichta ENSTSYG00000009210 I 0.896
tetur19g00770 Tetranychus urticae tetur19g00770 I 0.806
ENSTNIG00000003545 Tetraodon nigroviridis ENSTNIG00000003545 I 0.856
ENSTNIG00000002167 Tetraodon nigroviridis ENSTNIG00000002167 I 0.826
tefa Tetraodon nigroviridis ENSTNIG00000012940 I 0.848
ENSTNIG00000004400 Tetraodon nigroviridis ENSTNIG00000004400 I 0.805
hlfa Tetraodon nigroviridis ENSTNIG00000011274 I 0.842
ENSTNIG00000008098 Tetraodon nigroviridis ENSTNIG00000008098 I 0.819
TEF Tupaia belangeri ENSTBEG00000010576 I 0.847
HLF Tupaia belangeri ENSTBEG00000006958 I 0.896
HLF Tursiops truncatus ENSTTRG00000007194 I 0.896
TEF Tursiops truncatus ENSTTRG00000003365 I 0.847
Tal_R009182 Tyto alba Tal_R009182 I 0.893
Tal_R002658 Tyto alba Tal_R002658 I 0.847
TEF Vicugna pacos ENSVPAG00000002612 I 0.847
dbp.L Xenopus laevis XB-GENE-6256610 I 0.792
tef.S Xenopus laevis XB-GENE-962737 I 0.800
tef Xenopus tropicalis XB-GENE-962732 I 0.787
dbp Xenopus tropicalis XB-GENE-5995286 I 0.788
hlf Xenopus tropicalis XB-GENE-955698 I 0.826
XP_002937859 Xenopus tropicalis XP_002937859 I 0.826
ENSXMAG00000016939 Xiphophorus maculatus ENSXMAG00000016939 I 0.886
ENSXMAG00000014158 Xiphophorus maculatus ENSXMAG00000014158 I 0.783
ENSXMAG00000012903 Xiphophorus maculatus ENSXMAG00000012903 I 0.868
ENSXMAG00000012054 Xiphophorus maculatus ENSXMAG00000012054 I 0.806
ENSXMAG00000000678 Xiphophorus maculatus ENSXMAG00000000678 I 0.860