HHAL004160-PA (Halyomorpha halys)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00170 (bZIP_1) IPR011616 HHAL004160-PA T072788_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
CEBPB
M02851_2.00
Homo sapiens
VTTRCGCAAY

RTTGCGYAAB
SELEX
Jolma et al.(2013)
CEBPB_1
0.859 0.656
CEBPB
M02852_2.00
Homo sapiens
VTTRCGCAAY

RTTGCGYAAB
SELEX
Jolma et al.(2013)
CEBPB_2
0.859 0.656
CEBPB
M04331_2.00
Homo sapiens
NVTTRCGCAAYN

NRTTGCGYAABN
SELEX
Yin et al.(2017)
CEBPB_eDBD_HT-SELEX
0.859 0.656
CEBPB
M05840_2.00
Homo sapiens
RTTRCGYAAYM

KRTTRCGYAAY
SMiLE-seq
Isakova et al.(2017)
CEBPb
0.859 0.656
CEBPB
M07830_2.00
Homo sapiens
NNDRTKDYGCAAYN

NRTTGCRHMAYHNN
ChIP-seq
Gerstein et al.(2012)
HeLa-S3_CEBPB_Stanford
0.859 0.656
CEBPB
M07831_2.00
Homo sapiens
RTKRYGCAAYV

BRTTGCRYMAY
ChIP-seq
Gerstein et al.(2012)
HepG2_CEBPB_Stanford
0.859 0.656
CEBPB
M07832_2.00
Homo sapiens
DRTKRYGCAAYVNN

NNBRTTGCRYMAYH
ChIP-seq
Gerstein et al.(2012)
K562_CEBPB_Stanford
0.859 0.656
CEBPB
M08804_2.00
Homo sapiens
DRTKDHGCAAYV

BRTTGCDHMAYH
Misc
Kulakovskiy et al.(2013)
CEBPB_HUMAN.H11MO.0.A
0.859 0.656
CEBPB
M09993_2.00
Homo sapiens
RNRTKDDGHAAKNN

NNMTTDCHHMAYNY
Transfac
Matys et al.(2006)
V$CEBPB_01
0.859 0.656
CEBPB
M09994_2.00
Homo sapiens
NDRTKDHGCAABMH

DKVTTGCDHMAYHN
Transfac
Matys et al.(2006)
V$CEBPB_02
0.859 0.656
CEBPB
M09995_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPB_04
0.859 0.656
CEBPB
M09996_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPB_07
0.859 0.656
CEBPB
M09997_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPB_Q3
0.859 0.656
CEBPB
M09998_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPB_Q6
0.859 0.656
CEBPB
M04332_2.00
Homo sapiens
NRTTRCGCAAYN

NRTTGCGYAAYN
SELEX
Yin et al.(2017)
CEBPB_eDBD_Methyl-HT-SELEX
0.859 0.656
Cebpb
M02636_2.00
Mus musculus
VTKDYGYAAB

VTTRCRHMAB
PBM
Tillo et al.(2017)
CEBPB_C
0.856 0.656
Cebpb
M00999_2.00
Mus musculus
VTKDYGYAAB

VTTRCRHMAB
PBM
Mann et al.(2013)
CEBPB_UM_HK
0.856 0.656
Cebpb
M00761_2.00
Mus musculus
NTKDHGHAAB

VTTDCDHMAN
PBM
Weirauch et al.(2013)
pTH3208
0.856 0.656
Cebpb
M01818_2.00
Mus musculus
VTKDYGYAAB

VTTRCRHMAB
PBM
Weirauch et al.(2014)
pTH5460
0.856 0.656
Cebpb
M02867_2.00
Mus musculus
VTTRCGCAAY

RTTGCGYAAB
SELEX
Jolma et al.(2013)
Cebpb_1
0.856 0.656
Cebpb
M08841_2.00
Mus musculus
DRTKDHGCAAB

VTTGCDHMAYH
Misc
Kulakovskiy et al.(2013)
CEBPB_MOUSE.H11MO.0.A
0.856 0.656
Cebpb
M09498_2.00
Mus musculus
GTTGYRCAAT

ATTGYRCAAC
Misc
Heinz et al.(2010)
ThioMac-CEBPb_GSE21512
0.856 0.656
Cebpb
M02633_2.00
Mus musculus
VTKDNGHAAB

VTTDCNHMAB
PBM
Tillo et al.(2017)
CEBPB_5hmC
0.856 0.656
Cebpb
M02634_2.00
Mus musculus
TKDYGYAAYN

NRTTRCRHMA
PBM
Tillo et al.(2017)
CEBPB_5mCG
0.856 0.656
Cebpb
M02635_2.00
Mus musculus
YKDYGHAAYN

NRTTDCRHMR
PBM
Tillo et al.(2017)
CEBPB_5mC
0.856 0.656
Cebpb
M00998_2.00
Mus musculus
NTTDCGCAA

TTGCGHAAN
PBM
Mann et al.(2013)
CEBPB_M_HK
0.856 0.656
CEBPE
M02824_2.00
Homo sapiens
VTTRCGCAAY

RTTGCGYAAB
SELEX
Jolma et al.(2013)
CEBPE_1
0.842 0.609
CEBPE
M02729_2.00
Homo sapiens
VTTDYRHAAY

RTTDYRHAAB
SELEX
Jolma et al.(2010)
CEBPE_dimer
0.842 0.609
CEBPE
M04227_2.00
Homo sapiens
NRTTRCGCAAYN

NRTTGCGYAAYN
SELEX
Yin et al.(2017)
CEBPE_eDBD_HT-SELEX
0.842 0.609
CEBPE
M04009_2.00
Homo sapiens
NVTKRYRCAABN

NVTTGYRYMABN
SELEX
Rodriguez-Martinez et al.(2017)
CEBPE.1
0.842 0.609
CEBPE
M08783_2.00
Homo sapiens
VHDATTDCVHAM

KTDBGHAATHDB
Misc
Kulakovskiy et al.(2013)
CEBPE_HUMAN.H11MO.0.A
0.842 0.609
CEBPE
M09927_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPE_01
0.842 0.609
CEBPE
M09928_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPE_Q6_01
0.842 0.609
CEBPE
M09929_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPE_Q6
0.842 0.609
CEBPE
M04228_2.00
Homo sapiens
NRTTRCGCAAYN

NRTTGCGYAAYN
SELEX
Yin et al.(2017)
CEBPE_eDBD_Methyl-HT-SELEX
0.842 0.609
Cebpe
M01815_2.00
Mus musculus
TKDYGCAA

TTGCRHMA
PBM
Weirauch et al.(2014)
pTH5253
0.841 0.594
Cebpe
M08836_2.00
Mus musculus
VHDATTDCVHAM

KTDBGHAATHDB
Misc
Kulakovskiy et al.(2013)
CEBPE_MOUSE.H11MO.0.A
0.841 0.594
Cebpa
M00994_2.00
Mus musculus
TTDCGCAA

TTGCGHAA
PBM
Mann et al.(2013)
CEBPA_UM_HK
0.803 0.547
Cebpa
M01811_2.00
Mus musculus
VTKDYRHMAB

VTKDYRHMAB
PBM
Weirauch et al.(2014)
pTH5166
0.803 0.547
CEBPA
M04045_2.00
Homo sapiens
NVTKRCGCAABN

NVTTGCGYMABN
SELEX
Rodriguez-Martinez et al.(2017)
CEBPA.1
0.803 0.547
CEBPA
M08076_2.00
Homo sapiens
DRTTDTGCAAY

RTTGCAHAAYH
ChIP-seq
Mathelier et al.(2014)
MA0102.3
0.803 0.547
CEBPA
M08813_2.00
Homo sapiens
NVTKKWGCAABN

NVTTGCWMMABN
Misc
Kulakovskiy et al.(2013)
CEBPA_HUMAN.H11MO.0.A
0.803 0.547
Cebpa
M08830_2.00
Mus musculus
DVTKDNGCAAB

VTTGCNHMABH
Misc
Kulakovskiy et al.(2013)
CEBPA_MOUSE.H11MO.0.A
0.803 0.547
CEBPA
M10023_2.00
Homo sapiens
NNNWHWVCAMWBN

NVWKTGBWDWNNN
Transfac
Matys et al.(2006)
V$CEBP_01
0.803 0.547
CEBPA
M10024_2.00
Homo sapiens
NNNTKDNSYAAHNN

NNDTTRSNHMANNN
Transfac
Matys et al.(2006)
V$CEBPA_01
0.803 0.547
CEBPA
M10025_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPA_04
0.803 0.547
CEBPA
M10026_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPA_Q4
0.803 0.547
CEBPA
M10027_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CEBPA_Q6
0.803 0.547
CEBPA
M10028_2.00
Homo sapiens
NGWVTKHBGYAAKVBAYD

HRTVBMTTRCVDMABWCN
Transfac
Matys et al.(2006)
V$CEBP_C
0.803 0.547
CEBPA
M10029_2.00
Homo sapiens
NNNTKDHSCAANNN

NNNTTGSDHMANNN
Transfac
Matys et al.(2006)
V$CEBP_Q2
0.803 0.547
Cebpa
M00993_2.00
Mus musculus
NTTDCGCAA

TTGCGHAAN
PBM
Mann et al.(2013)
CEBPA_M_HK
0.803 0.547
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL004160-PA bZIP 155 218

Links

Other bZIP family TFs
Other Halyomorpha halys TFs

141 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
CLEC002077 Cimex lectularius CLEC002077 I 0.888
ACYPI003971 Acyrthosiphon pisum ACYPI003971 I 0.870
L798_13978 Zootermopsis nevadensis L798_13978 I 0.866
PHUM433250 Pediculus humanus PHUM433250 I 0.866
TC009220 Tribolium castaneum TC009220 I 0.864
YQE_11799 Dendroctonus ponderosae YQE_11799 I 0.864
ENSMMUG00000004874 Macaca mulatta ENSMMUG00000004874 I 0.859
ENSMODG00000016314 Monodelphis domestica ENSMODG00000016314 I 0.859
ENSMPUG00000019019 Mustela putorius furo ENSMPUG00000019019 I 0.859
CEBPB Myotis lucifugus ENSMLUG00000002060 I 0.859
CEBPB Homo sapiens ENSG00000172216 D 0.859
ENSOARG00000013395 Ovis aries ENSOARG00000013395 I 0.859
CEBPB Gorilla gorilla ENSGGOG00000025010 I 0.859
ENSLAFG00000026180 Loxodonta africana ENSLAFG00000026180 I 0.859
ENSMEUG00000000063 Macropus eugenii ENSMEUG00000000063 I 0.859
CEBPB Pan troglodytes ENSPTRG00000041263 I 0.859
ENSSSCG00000024816 Sus scrofa ENSSSCG00000024816 I 0.859
ENSSSCG00000028739 Sus scrofa ENSSSCG00000028739 I 0.859
CEBPB Tursiops truncatus ENSTTRG00000003985 I 0.859
Cebpb Rattus norvegicus ENSRNOG00000057347 I 0.859
CEBPB Pteropus vampyrus ENSPVAG00000003541 I 0.859
ENSPANG00000007537 Papio anubis ENSPANG00000007537 I 0.859
ENSPPYG00000011124 Pongo abelii ENSPPYG00000011124 I 0.859
CEBPB Dasypus novemcinctus ENSDNOG00000041573 I 0.859
CEBPB Otolemur garnettii ENSOGAG00000026467 I 0.859
CEBPB Oryctolagus cuniculus ENSOCUG00000024667 I 0.859
CEBPB Canis familiaris ENSCAFG00000031326 I 0.859
CEBPB Callithrix jacchus ENSCJAG00000000526 I 0.859
ENSAMEG00000013456 Ailuropoda melanoleuca ENSAMEG00000013456 I 0.859
ENSCPOG00000000811 Cavia porcellus ENSCPOG00000000811 I 0.859
ENSCSAG00000018746 Chlorocebus sabaeus ENSCSAG00000018746 I 0.859
Ogr08532 Ophisaurus gracilis Ogr08532 I 0.856
CEBPB Gallus gallus ENSGALG00000008014 I 0.856
Cebpb Mus musculus ENSMUSG00000056501 D 0.856
ENSFALG00000014081 Ficedula albicollis ENSFALG00000014081 I 0.856
CEBPB Anolis carolinensis ENSACAG00000015567 I 0.856
CEBPB Taeniopygia guttata ENSTGUG00000008707 I 0.856
Pvit_03335 Pogona vitticeps Pvit_03335 I 0.855
LDEC017703 Leptinotarsa decemlineata LDEC017703 I 0.850
Cmyd_10017449 Chelonia mydas Cmyd_10017449 I 0.845
cebpa Danio rerio ENSDARG00000036074 I 0.843
ENSLOCG00000017586 Lepisosteus oculatus ENSLOCG00000017586 I 0.843
ENSOARG00000019360 Ovis aries ENSOARG00000019360 I 0.842
ENSOANG00000007645 Ornithorhynchus anatinus ENSOANG00000007645 I 0.842
ENSNLEG00000014958 Nomascus leucogenys ENSNLEG00000014958 I 0.842
CEBPE Callithrix jacchus ENSCJAG00000008065 I 0.842
CEBPE Oryctolagus cuniculus ENSOCUG00000022235 I 0.842
CEBPE Otolemur garnettii ENSOGAG00000001312 I 0.842
CEBPE Tursiops truncatus ENSTTRG00000017229 I 0.842
ENSPANG00000019646 Papio anubis ENSPANG00000019646 I 0.842
CEBPE Sus scrofa ENSSSCG00000002033 I 0.842
ENSCAFG00000011433 Canis familiaris ENSCAFG00000011433 I 0.842
CEBPE Bos taurus ENSBTAG00000005952 I 0.842
CEBPE Pan troglodytes ENSPTRG00000006162 I 0.842
ENSPPYG00000005659 Pongo abelii ENSPPYG00000005659 I 0.842
ENSSTOG00000007204 Ictidomys tridecemlineatus ENSSTOG00000007204 I 0.842
CEBPE Equus caballus ENSECAG00000012883 I 0.842
ENSTBEG00000017246 Tupaia belangeri ENSTBEG00000017246 I 0.842
CEBPE Cavia porcellus ENSCPOG00000014049 I 0.842
ENSP00000206513 Macaca fascicularis ENSP00000206513 I 0.842
ENSMICG00000002591 Microcebus murinus ENSMICG00000002591 I 0.842
CEBPE Myotis lucifugus ENSMLUG00000030209 I 0.842
Myotis_brandtii_CEBPE_10009435 Myotis brandtii Myotis_brandtii_CEBPE_10009435 I 0.842
CEBPE Gorilla gorilla ENSGGOG00000007419 I 0.842
CEBPE Felis catus ENSFCAG00000002334 I 0.842
CEBPE Homo sapiens ENSG00000092067 D 0.842
ENSCSAG00000016086 Chlorocebus sabaeus ENSCSAG00000016086 I 0.842
ENSP00000206513-D1 Bos grunniens ENSP00000206513-D1 I 0.842
ENSMPUG00000006815 Mustela putorius furo ENSMPUG00000006815 I 0.842
ENSAMEG00000007625 Ailuropoda melanoleuca ENSAMEG00000007625 I 0.842
CEBPE Erinaceus europaeus ENSEEUG00000005848 I 0.842
CEBPE Macaca mulatta ENSMMUG00000019652 I 0.842
Cebpe Mus musculus ENSMUSG00000052435 D 0.841
ENSSHAG00000013989 Sarcophilus harrisii ENSSHAG00000013989 I 0.841
Cebpe Rattus norvegicus ENSRNOG00000014282 I 0.841
CEBPE Monodelphis domestica ENSMODG00000004586 I 0.841
cebpb Xenopus tropicalis XB-GENE-479779 I 0.840
cebpb.L Xenopus laevis XB-GENE-865306 I 0.840
ENSLACG00000002076 Latimeria chalumnae ENSLACG00000002076 I 0.839
ENSLACG00000005924 Latimeria chalumnae ENSLACG00000005924 I 0.833
NV14868 Nasonia vitripennis NV14868 I 0.830
Hsal_02456--XP_394681.2_APIME Harpegnathos saltator Hsal_02456--XP_394681.2_APIME I 0.830
cebpa Takifugu rubripes ENSTRUG00000006383 I 0.827
ACEP26309 Atta cephalotes ACEP26309 I 0.826
GB44204 Apis mellifera GB44204 I 0.826
Cflo_01516--XP_394681.2_APIME Camponotus floridanus Cflo_01516--XP_394681.2_APIME I 0.826
cebpa Tetraodon nigroviridis ENSTNIG00000003102 I 0.825
CEBPE Anolis carolinensis ENSACAG00000007268 I 0.825
ENSAMXG00000026122 Astyanax mexicanus ENSAMXG00000026122 I 0.825
Ogr08265 Ophisaurus gracilis Ogr08265 I 0.825
cebpb Takifugu rubripes ENSTRUG00000007449 I 0.824
ENSXMAG00000019665 Xiphophorus maculatus ENSXMAG00000019665 I 0.824
ENSAMXG00000018723 Astyanax mexicanus ENSAMXG00000018723 I 0.824
ENSPFOG00000020954 Poecilia formosa ENSPFOG00000020954 I 0.824
ENSONIG00000021137 Oreochromis niloticus ENSONIG00000021137 I 0.824
ENSGMOG00000019534 Gadus morhua ENSGMOG00000019534 I 0.824
cebpb Danio rerio ENSDARG00000042725 I 0.824
cebpb Oryzias latipes ENSORLG00000015032 I 0.824
SINV13631 Solenopsis invicta SINV13631 I 0.823
EBP Gallus gallus ENSGALG00000026525 I 0.822
ENSXMAG00000019692 Xiphophorus maculatus ENSXMAG00000019692 I 0.821
ENSONIG00000003300 Oreochromis niloticus ENSONIG00000003300 I 0.821
CAA76309 Xenopus laevis CAA76309 I 0.821
ENSPFOG00000019930 Poecilia formosa ENSPFOG00000019930 I 0.821
cebpa Xenopus tropicalis XB-GENE-853397 I 0.821
ENSOARG00000004414 Ovis aries ENSOARG00000004414 I 0.820
ENSAMEG00000008255 Ailuropoda melanoleuca ENSAMEG00000008255 I 0.820
CEBPE Procavia capensis ENSPCAG00000015039 I 0.819
CEBPE Echinops telfairi ENSETEG00000000035 I 0.819
CEBPE Loxodonta africana ENSLAFG00000031400 I 0.819
DAPPUDRAFT_18594 Daphnia pulex DAPPUDRAFT_18594 I 0.819
cebpa.L Xenopus laevis XB-GENE-855405 I 0.814
ENSLOCG00000018358 Lepisosteus oculatus ENSLOCG00000018358 I 0.812
cebpa Oryzias latipes ENSORLG00000018660 I 0.808
cebpe Xenopus tropicalis XB-GENE-853430 I 0.807
CEBPE Pteropus vampyrus ENSPVAG00000005264 I 0.807
Alligator_sinensis_CCG003052.1 Alligator sinensis Alligator_sinensis_CCG003052.1 I 0.804
CEBPA Loxodonta africana ENSLAFG00000030435 I 0.803
CEBPA Homo sapiens ENSG00000245848 D 0.803
ENSFALG00000007785 Ficedula albicollis ENSFALG00000007785 I 0.803
CEBPA Dasypus novemcinctus ENSDNOG00000041488 I 0.803
ENSCSAG00000018515 Chlorocebus sabaeus ENSCSAG00000018515 I 0.803
ENSCAFG00000007407 Canis familiaris ENSCAFG00000007407 I 0.803
ENSCPOG00000023297 Cavia porcellus ENSCPOG00000023297 I 0.803
CEBPA Pan troglodytes ENSPTRG00000038687 I 0.803
ENSSHAG00000014918 Sarcophilus harrisii ENSSHAG00000014918 I 0.803
CEBPA Taeniopygia guttata ENSTGUG00000009472 I 0.803
ENSPANG00000002974 Papio anubis ENSPANG00000002974 I 0.803
ENSPSIG00000000363 Pelodiscus sinensis ENSPSIG00000000363 I 0.803
CEBPA Otolemur garnettii ENSOGAG00000024661 I 0.803
CEBPA Ornithorhynchus anatinus ENSOANG00000008144 I 0.803
CEBPA Macaca mulatta ENSMMUG00000006124 I 0.803
CEBPA Sus scrofa ENSSSCG00000002866 I 0.803
Cebpa Rattus norvegicus ENSRNOG00000010918 I 0.803
Cebpa Mus musculus ENSMUSG00000034957 D 0.803
ENSMPUG00000007593 Mustela putorius furo ENSMPUG00000007593 I 0.803
Afo_R013999 Aptenodytes forsteri Afo_R013999 I 0.799
cebpa.S Xenopus laevis XB-GENE-17335551 I 0.796
tetur13g00160 Tetranychus urticae tetur13g00160 N 0.794
cebpb Gasterosteus aculeatus ENSGACG00000011827 I 0.789
ENSPMAG00000004124 Petromyzon marinus ENSPMAG00000004124 I 0.782