TF Information

HHAL005759-PA *(Halyomorpha halys)* bZIP
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00170 (bZIP_1)	IPR011616	HHAL005759-PA	T072789_2.00	Misc (2018-Jan-19)
NCBI Gene Info: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
HLF M02831_2.00	Homo sapiens	NRTTAYRTAABN	NVTTAYRTAAYN	SELEX Jolma et al.(2013) HLF_1	0.786	0.547
Hlf M02860_2.00	Mus musculus	KRTTACGTAAYN	NRTTACGTAAYM	SELEX Jolma et al.(2013) Hlf_1	0.786	0.547
HLF M04245_2.00	Homo sapiens	NVTTRCRYAABN	NVTTRYGYAABN	SELEX Yin et al.(2017) HLF_FL_HT-SELEX	0.786	0.547
HLF M04016_2.00	Homo sapiens	RTKAYRTAAB	VTTAYRTMAY	SELEX Rodriguez-Martinez et al.(2017) HLF.1	0.786	0.547
HLF M08786_2.00	Homo sapiens	NRTTRYGTAAYMS	SKRTTACRYAAYN	Misc Kulakovskiy et al.(2013) HLF_HUMAN.H11MO.0.C	0.786	0.547
Hlf M08815_2.00	Mus musculus	VTTRTGYAABH	DVTTRCAYAAB	Misc Kulakovskiy et al.(2013) HLF_MOUSE.H11MO.0.C	0.786	0.547
HLF M09937_2.00	Homo sapiens	ATKRYGTAAY	RTTACRYMAT	Transfac Matys et al.(2006) V$HLF_01	0.786	0.547
HLF M04246_2.00	Homo sapiens	NVTTRCRYAABN	NVTTRYGYAABN	SELEX Yin et al.(2017) HLF_FL_Methyl-HT-SELEX	0.786	0.547
Tef M01803_2.00	Mus musculus	NVTTRYVNNN	NNNBRYAABN	PBM Weirauch et al.(2014) pTH5078	0.786	0.547
TEF M02849_2.00	Homo sapiens	NRTTAYGTAAYN	NRTTACRTAAYN	SELEX Jolma et al.(2013) TEF_1	0.786	0.547
TEF M02850_2.00	Homo sapiens	NVTTAYGTAABN	NVTTACRTAABN	SELEX Jolma et al.(2013) TEF_2	0.786	0.547
TEF M04325_2.00	Homo sapiens	NRTTACGTAAYN	NRTTACGTAAYN	SELEX Yin et al.(2017) TEF_eDBD_HT-SELEX	0.786	0.547
TEF M09983_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TEF_05	0.786	0.547
TEF M09984_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TEF_06	0.786	0.547
TEF M09985_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TEF_Q6	0.786	0.547
TEF M09986_2.00	Homo sapiens	MTKAYGTAAY	RTTACRTMAK	Transfac Matys et al.(2006) V$VBP_01	0.786	0.547
TEF M04326_2.00	Homo sapiens	NRTTACRTAAYN	NRTTAYGTAAYN	SELEX Yin et al.(2017) TEF_eDBD_Methyl-HT-SELEX	0.786	0.547
CG7786 M03653_2.00	Drosophila melanogaster	NRTTAYRTAAYN	NRTTAYRTAAYN	SELEX Nitta et al.(2015) CG7786_1	0.783	0.672
For this family, TFs with SR scores > 0.782* will likely have a similar motif*