Zfhx3 (Mus musculus)
C2H2 ZF,Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2)
PF00046 (Homeobox) 		IPR007087
IPR001356 		ENSMUSG00000038872 T075921_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of cell adhesion; regulation of gene expression; and regulation of locomotor rhythm. Located in mitochondrion. Is expressed in several structures, including central nervous system; eye; foot; genitourinary system; and lung. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human ZFHX3 (zinc finger homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZFHX3
M10088_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AFP1_Q6 		0.996 0.996
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000044612 C2H2 ZF 672 695
ENSMUSP00000044612 C2H2 ZF 727 751
ENSMUSP00000044612 C2H2 ZF 805 829
ENSMUSP00000044612 C2H2 ZF 1089 1113
ENSMUSP00000044612 C2H2 ZF 1370 1395
ENSMUSP00000044612 C2H2 ZF 1411 1433
ENSMUSP00000044612 C2H2 ZF 1439 1462
ENSMUSP00000044612 C2H2 ZF 1555 1579
ENSMUSP00000044612 C2H2 ZF 1606 1630
ENSMUSP00000044612 Homeodomain 2153 2209
ENSMUSP00000044612 Homeodomain 2250 2306
ENSMUSP00000044612 C2H2 ZF 2335 2356
ENSMUSP00000044612 C2H2 ZF 2539 2561
ENSMUSP00000044612 Homeodomain 2651 2707
ENSMUSP00000044612 C2H2 ZF 2721 2743
ENSMUSP00000044612 Homeodomain 2955 3011

Links

Other C2H2 ZF,Homeodomain family TFs
Other Mus musculus TFs

114 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSMPUG00000007747 Mustela putorius furo ENSMPUG00000007747 I 1.000
ZFHX3 Felis catus ENSFCAG00000023839 I 1.000
Zfhx3 Rattus norvegicus ENSRNOG00000014452 I 1.000
ENSAMEG00000002197 Ailuropoda melanoleuca ENSAMEG00000002197 I 1.000
ZFHX3 Dasypus novemcinctus ENSDNOG00000046047 I 0.998
ZFHX3 Echinops telfairi ENSETEG00000014223 I 0.998
ZFHX3 Equus caballus ENSECAG00000022984 I 0.998
ZFHX3 Microcebus murinus ENSMICG00000003537 I 0.998
ENSOCUG00000017910 Oryctolagus cuniculus ENSOCUG00000017910 I 0.998
ENSP00000268489 Macaca fascicularis ENSP00000268489 I 0.998
ENSPPYG00000007513 Pongo abelii ENSPPYG00000007513 I 0.998
ENSPANG00000010456 Papio anubis ENSPANG00000010456 I 0.998
ENSCSAG00000004171 Chlorocebus sabaeus ENSCSAG00000004171 I 0.998
ZFHX3 Macaca mulatta ENSMMUG00000021041 I 0.998
ZFHX3 Ornithorhynchus anatinus ENSOANG00000005084 I 0.998
ZFHX3 Canis familiaris ENSCAFG00000020243 I 0.998
ZFHX3 Cavia porcellus ENSCPOG00000009111 I 0.998
ZFHX3 Gorilla gorilla ENSGGOG00000012083 I 0.996
ZFHX3 Gallus gallus ENSGALG00000000713 I 0.996
ZFHX3 Homo sapiens ENSG00000140836 D 0.996
ZFHX3 Loxodonta africana ENSLAFG00000017476 I 0.996
ZFHX3 Bos taurus ENSBTAG00000014636 I 0.996
ZFHX3 Pan troglodytes ENSPTRG00000008340 I 0.996
ENSOARG00000003669 Ovis aries ENSOARG00000003669 I 0.996
ENSBTAP00000019489-D1 Bos grunniens ENSBTAP00000019489-D1 I 0.996
ZFHX3 Myotis lucifugus ENSMLUG00000016100 I 0.996
ZFHX3 Monodelphis domestica ENSMODG00000002600 I 0.992
ENSSHAG00000014394 Sarcophilus harrisii ENSSHAG00000014394 I 0.992
zfhx3 Xenopus tropicalis XB-GENE-853731 I 0.992
ZFHX3 Taeniopygia guttata ENSTGUG00000008190 I 0.990
ENSFALG00000002706 Ficedula albicollis ENSFALG00000002706 I 0.986
ENSLACG00000015046 Latimeria chalumnae ENSLACG00000015046 I 0.982
Pvit_16272 Pogona vitticeps Pvit_16272 I 0.980
ENSLOCG00000004206 Lepisosteus oculatus ENSLOCG00000004206 I 0.978
ENSAMXG00000004340 Astyanax mexicanus ENSAMXG00000004340 I 0.978
zfhx3 Danio rerio ENSDARG00000103057 I 0.978
zfhx3 Oryzias latipes ENSORLG00000007874 I 0.976
ENSONIG00000005914 Oreochromis niloticus ENSONIG00000005914 I 0.970
ENSPFOG00000001702 Poecilia formosa ENSPFOG00000001702 I 0.968
ENSGMOG00000002909 Gadus morhua ENSGMOG00000002909 I 0.966
zfhx3 Takifugu rubripes ENSTRUG00000017601 I 0.964
Gfo_R000560 Geospiza fortis Gfo_R000560 I 0.916
ZFHX3 Erinaceus europaeus ENSEEUG00000008705 I 0.902
ENSPSIG00000003765 Pelodiscus sinensis ENSPSIG00000003765 I 0.878
ZFHX4 Pteropus vampyrus ENSPVAG00000004200 I 0.876
ZFHX4 Otolemur garnettii ENSOGAG00000000486 I 0.876
ENSOARG00000007353 Ovis aries ENSOARG00000007353 I 0.876
ZFHX4 Bos taurus ENSBTAG00000033268 I 0.876
ENSMPUG00000010092 Mustela putorius furo ENSMPUG00000010092 I 0.876
ENSP00000382394-D1 Bos grunniens ENSP00000382394-D1 I 0.876
ZFHX4 Canis familiaris ENSCAFG00000008310 I 0.876
ZFHX4 Felis catus ENSFCAG00000015688 I 0.876
ZFHX4 Sorex araneus ENSSARG00000001090 I 0.875
ZFHX3 Callithrix jacchus ENSCJAG00000015112 I 0.875
ZFHX4 Callithrix jacchus ENSCJAG00000000517 I 0.875
ZFHX4 Cavia porcellus ENSCPOG00000012693 I 0.875
ZFHX4 Equus caballus ENSECAG00000022611 I 0.875
ZFHX4 Oryctolagus cuniculus ENSOCUG00000001723 I 0.875
XP_002939633 Xenopus tropicalis XP_002939633 I 0.875
ZFHX4 Loxodonta africana ENSLAFG00000014395 I 0.875
Zfhx3 Dipodomys ordii ENSDORG00000016147 I 0.875
ZFHX4 Gorilla gorilla ENSGGOG00000024837 I 0.875
ENSAMXG00000013609 Astyanax mexicanus ENSAMXG00000013609 I 0.873
ENSPANG00000023610 Papio anubis ENSPANG00000023610 I 0.873
ZFHX4 Tupaia belangeri ENSTBEG00000012567 I 0.873
ENSP00000382394 Macaca fascicularis ENSP00000382394 I 0.873
ZFHX4 Homo sapiens ENSG00000091656 I 0.873
ENSCSAG00000013465 Chlorocebus sabaeus ENSCSAG00000013465 I 0.873
ZFHX3 Tursiops truncatus ENSTTRG00000002935 I 0.873
ENSSTOG00000024425 Ictidomys tridecemlineatus ENSSTOG00000024425 I 0.871
zfhx4 Danio rerio ENSDARG00000075542 I 0.869
Zfhx4 Rattus norvegicus ENSRNOG00000008765 I 0.865
ZFHX4 Sus scrofa ENSSSCG00000006169 I 0.865
ZFHX3 Sorex araneus ENSSARG00000011764 I 0.859
ZFHX3 Sus scrofa ENSSSCG00000002752 I 0.859
ZFHX4 Pan troglodytes ENSPTRG00000020358 I 0.856
ZFHX3 Anolis carolinensis ENSACAG00000008238 I 0.851
ZFHX3 Procavia capensis ENSPCAG00000010600 I 0.851
ENSAPLG00000002327 Anas platyrhynchos ENSAPLG00000002327 I 0.850
Aan_R009157 Calypte anna Aan_R009157 I 0.850
Afo_R007434 Aptenodytes forsteri Afo_R007434 I 0.850
ZFHX3 Meleagris gallopavo ENSMGAG00000008764 I 0.848
Ogr16853 Ophisaurus gracilis Ogr16853 I 0.843
ENSAMEG00000016203 Ailuropoda melanoleuca ENSAMEG00000016203 I 0.840
zfhx4 Takifugu rubripes ENSTRUG00000000173 I 0.836
zfhx4 Gasterosteus aculeatus ENSGACG00000002418 I 0.830
Zfhx4 Mus musculus ENSMUSG00000025255 I 0.830
ENSXMAG00000000693 Xiphophorus maculatus ENSXMAG00000000693 I 0.830
ENSPFOG00000009152 Poecilia formosa ENSPFOG00000009152 I 0.830
ENSONIG00000014495 Oreochromis niloticus ENSONIG00000014495 I 0.829
zfhx4 Oryzias latipes ENSORLG00000006928 I 0.829
ENSSTOG00000027206 Ictidomys tridecemlineatus ENSSTOG00000027206 I 0.815
Myotis_brandtii_ZFHX3_10022430 Myotis brandtii Myotis_brandtii_ZFHX3_10022430 I 0.815
ZFHX3 Otolemur garnettii ENSOGAG00000010886 I 0.815
Alligator_sinensis_CCG000692.1 Alligator sinensis Alligator_sinensis_CCG000692.1 I 0.813
zfhx3 Gasterosteus aculeatus ENSGACG00000015779 I 0.795
si:ch73-386h18.1 Danio rerio ENSDARG00000073944 I 0.791
ENSPSIG00000004618 Pelodiscus sinensis ENSPSIG00000004618 I 0.779
ZFHX4 Microcebus murinus ENSMICG00000008252 I 0.777
ENSPPYG00000018687 Pongo abelii ENSPPYG00000018687 I 0.775
Afo_R013178 Aptenodytes forsteri Afo_R013178 I 0.765
ENSGALG00000015673 Gallus gallus ENSGALG00000015673 I 0.765
Gfo_R007559 Geospiza fortis Gfo_R007559 I 0.765
ENSSHAG00000013776 Sarcophilus harrisii ENSSHAG00000013776 I 0.765
ENSFALG00000008584 Ficedula albicollis ENSFALG00000008584 I 0.765
ZFHX4 Monodelphis domestica ENSMODG00000006777 I 0.765
Tal_R008844 Tyto alba Tal_R008844 I 0.765
Aan_R002979 Calypte anna Aan_R002979 I 0.765
Pvit_00058 Pogona vitticeps Pvit_00058 I 0.763
ENSAPLG00000012910 Anas platyrhynchos ENSAPLG00000012910 I 0.763
ENSLOCG00000013472 Lepisosteus oculatus ENSLOCG00000013472 I 0.757
ENSNLEG00000001972 Nomascus leucogenys ENSNLEG00000001972 I 0.711
Cflo_00361--XP_393785.3_APIME Camponotus floridanus Cflo_00361--XP_393785.3_APIME I 0.709
ENSMGAG00000011602 Meleagris gallopavo ENSMGAG00000011602 I 0.705