CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Zfhx3
(
Mus musculus
)
C2H2 ZF,Homeodomain
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
PF00046 (Homeobox)
IPR007087
IPR001356
ENSMUSG00000038872
T075921_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of cell adhesion; regulation of gene expression; and regulation of locomotor rhythm. Located in mitochondrion. Is expressed in several structures, including central nervous system; eye; foot; genitourinary system; and lung. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human ZFHX3 (zinc finger homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
ZFHX3
M10088_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AFP1_Q6
0.996
0.996
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSMUSP00000044612
C2H2 ZF
672
695
LKCPKCNWHYKYQQTLEAHMKEKH
ENSMUSP00000044612
C2H2 ZF
727
751
FRCEVCNYSTTTKGNLSIHMQSDKH
ENSMUSP00000044612
C2H2 ZF
805
829
WRCEVCDYETNVARNLRIHMTSEKH
ENSMUSP00000044612
C2H2 ZF
1089
1113
YHCVLCNYSTKAKLNLIQHVRSMKH
ENSMUSP00000044612
C2H2 ZF
1370
1395
FLCWKKGCNQVFKTSATLQTHFNEVH
ENSMUSP00000044612
C2H2 ZF
1411
1433
YRCNQCSLAFKTIEKLQLHSQYH
ENSMUSP00000044612
C2H2 ZF
1439
1462
TMCCLCQRSFRTFQALKKHLETSH
ENSMUSP00000044612
C2H2 ZF
1555
1579
YKCTVCKESFTQKNILLVHYNSVSH
ENSMUSP00000044612
C2H2 ZF
1606
1630
FKCNTCNVAYSQSSTLEIHMRSVLH
ENSMUSP00000044612
Homeodomain
2153
2209
KRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQ
ENSMUSP00000044612
Homeodomain
2250
2306
RSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK
ENSMUSP00000044612
C2H2 ZF
2335
2356
YQCKKCSLVFQRIFDLIKHQKK
ENSMUSP00000044612
C2H2 ZF
2539
2561
YQCDQCKLAFPSFEHWQEHQQLH
ENSMUSP00000044612
Homeodomain
2651
2707
KRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK
ENSMUSP00000044612
C2H2 ZF
2721
2743
RCPFCRALFKAKTALEAHIRSRH
ENSMUSP00000044612
Homeodomain
2955
3011
KRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKK
Links
Other
C2H2 ZF,Homeodomain
family TFs
Other
Mus musculus
TFs
114 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy