Zfhx3 (Mus musculus)
C2H2 ZF,Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2)
PF00046 (Homeobox) 		IPR007087
IPR001356 		ENSMUSG00000038872 T075921_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of cell adhesion; regulation of gene expression; and regulation of locomotor rhythm. Located in mitochondrion. Is expressed in several structures, including central nervous system; eye; foot; genitourinary system; and lung. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human ZFHX3 (zinc finger homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZFHX3
M10088_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AFP1_Q6 		0.996 0.996
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000044612 C2H2 ZF 672 695
ENSMUSP00000044612 C2H2 ZF 727 751
ENSMUSP00000044612 C2H2 ZF 805 829
ENSMUSP00000044612 C2H2 ZF 1089 1113
ENSMUSP00000044612 C2H2 ZF 1370 1395
ENSMUSP00000044612 C2H2 ZF 1411 1433
ENSMUSP00000044612 C2H2 ZF 1439 1462
ENSMUSP00000044612 C2H2 ZF 1555 1579
ENSMUSP00000044612 C2H2 ZF 1606 1630
ENSMUSP00000044612 Homeodomain 2153 2209
ENSMUSP00000044612 Homeodomain 2250 2306
ENSMUSP00000044612 C2H2 ZF 2335 2356
ENSMUSP00000044612 C2H2 ZF 2539 2561
ENSMUSP00000044612 Homeodomain 2651 2707
ENSMUSP00000044612 C2H2 ZF 2721 2743
ENSMUSP00000044612 Homeodomain 2955 3011

Links

Other C2H2 ZF,Homeodomain family TFs
Other Mus musculus TFs

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114 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action