CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ENSP00000319248
(
Macaca fascicularis
)
C2H2 ZF,Homeodomain
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
PF00096 (zf-C2H2)
PF00046 (Homeobox)
IPR007087
IPR001356
ENSP00000319248
T076236_2.00
GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
ZEB1
M08080_2.00
Homo sapiens
NNCACCTGBNN
NNVCAGGTGNN
ChIP-seq
Mathelier et al.(2014)
MA0103.3
1.000
1.000
ZEB1
M07842_2.00
Homo sapiens
YNCACCTG
CAGGTGNR
ChIP-seq
Gerstein et al.(2012)
GM12878_ZEB1_HudsonAlpha
1.000
1.000
ZEB1
M08190_2.00
Homo sapiens
CVCWCACCTG
CAGGTGWGBG
ChIP-seq
Contrino et al.(2012)
Mv136
1.000
1.000
ZEB1
M08848_2.00
Homo sapiens
YHYACCTGBV
BVCAGGTRDR
Misc
Kulakovskiy et al.(2013)
ZEB1_HUMAN.H11MO.0.A
1.000
1.000
ZEB1
M10089_2.00
Homo sapiens
NHYDYACCTGWVY
RBWCAGGTRHRDN
Transfac
Matys et al.(2006)
V$AREB6_01
1.000
1.000
ZEB1
M10090_2.00
Homo sapiens
WHWCACCTKWNN
NNWMAGGTGWDW
Transfac
Matys et al.(2006)
V$AREB6_02
1.000
1.000
ZEB1
M10091_2.00
Homo sapiens
VBRCACCTGKDV
BHMCAGGTGYVB
Transfac
Matys et al.(2006)
V$AREB6_03
1.000
1.000
ZEB1
M10092_2.00
Homo sapiens
NNSAAACVB
VBGTTTSNN
Transfac
Matys et al.(2006)
V$AREB6_04
1.000
1.000
ZEB1
M10093_2.00
Homo sapiens
NHNCACCTDRV
BYHAGGTGNDN
Transfac
Matys et al.(2006)
V$DELTAEF1_01
1.000
1.000
ZEB1
M10094_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$ZEB1_03
1.000
1.000
ZEB1
M10095_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$ZEB_Q3
1.000
1.000
Zeb1
M05844_2.00
Mus musculus
NYACCTGN
NCAGGTRN
SMiLE-seq
Isakova et al.(2017)
ZEB1
0.986
0.986
Zeb1
M08849_2.00
Mus musculus
YHYACCTGBV
BVCAGGTRDR
Misc
Kulakovskiy et al.(2013)
ZEB1_MOUSE.H11MO.0.B
0.986
0.986
ZEB2
M10096_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIP1_Q6
0.837
0.837
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000319248
C2H2 ZF
152
175
LTCPYCDRGYKRFTSLKEHIKYRH
ENSP00000319248
C2H2 ZF
182
204
FSCSLCSYTFAYRTQLERHMTSH
ENSP00000319248
C2H2 ZF
222
244
FKCTECGKAFKYKHHLKEHLRIH
ENSP00000319248
C2H2 ZF
250
271
YECPNCKKRFSHSGSYSSHISS
ENSP00000319248
Homeodomain
568
616
QPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLPLDVVKKWFEKMQA
ENSP00000319248
C2H2 ZF
886
908
YACDLCDKIFQKSSSLLRHKYEH
ENSP00000319248
C2H2 ZF
914
936
HECGICKKAFKHKHHLIEHMRLH
ENSP00000319248
C2H2 ZF
942
963
YQCDKCGKRFSHSGSYSQHMNH
Links
Other
C2H2 ZF,Homeodomain
family TFs
Other
Macaca fascicularis
TFs
126 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy