fezf1 (Danio rerio)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSDARG00000010270 T090827_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cell differentiation and nervous system development. Predicted to be located in nucleus. Is expressed in hypothalamus. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 22 with or without anosmia. Orthologous to human FEZF1 (FEZ family zinc finger 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
FEZF1
M08307_2.00 		Homo sapiens
NNBTGYYYTTTTNNN
NNNAAAARRRCAVNN		 ChIP-seq
Schmitges et al.(2016)
A0PJY2_1-5.RCADE 		0.819 0.986
FEZF1
M08889_2.00 		Homo sapiens
DYTGYYCWTTTN
NAAAWGRRCARH		 Misc
Kulakovskiy et al.(2013)
FEZF1_HUMAN.H11MO.0.C 		0.819 0.986
erm
M03686_2.00 		Drosophila melanogaster
TGATTGCTCWTTT
AAAWGAGCAATCA		 SELEX
Nitta et al.(2015)
CG31670_1 		0.798 0.899
erm
M06128_2.00 		Drosophila melanogaster
KWTGYKCWTTT
AAAWGMRCAWM		 B1H
Zhu et al.(2011)
CG31670_SANGER_5_FBgn0031375 		0.798 0.899
erm
M06129_2.00 		Drosophila melanogaster
BBRTTGCTCWTTTBN
NVAAAWGAGCAAYVV		 B1H
Zhu et al.(2011)
CG31670_SOLEXA_5_FBgn0031375 		0.798 0.899
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000007655 C2H2 ZF 247 269
ENSDARP00000007655 C2H2 ZF 275 297
ENSDARP00000007655 C2H2 ZF 303 325
ENSDARP00000007655 C2H2 ZF 331 353
ENSDARP00000007655 C2H2 ZF 359 381
ENSDARP00000007655 C2H2 ZF 387 410

Links

Other C2H2 ZF family TFs
Other Danio rerio TFs

Invalid Input OrderBy

171 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action