klf11a (Danio rerio)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSDARG00000030844 T090878_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 7 and type 2 diabetes mellitus. Orthologous to human KLF11 (Kruppel like factor 11). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
KLF11
M00242_2.00 		Homo sapiens
MCGCCCCC
GGGGGCGK		 PBM
Barrera et al.(2016)
KLF11_REF 		0.804 0.928
KLF11
M04554_2.00 		Homo sapiens
VMCMCRCCCMYNMCACGCCCMC
GKGGGCGTGKNRKGGGYGKGKB		 SELEX
Yin et al.(2017)
KLF11_eDBD_HT-SELEX 		0.804 0.928
KLF11
M10261_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FKLF_Q5 		0.804 0.928
KLF11
M00241_2.00 		Homo sapiens
MCGCCCMC
GKGGGCGK		 PBM
Barrera et al.(2016)
KLF11_R402Q 		0.804 0.928
KLF11
M04555_2.00 		Homo sapiens
VMCMCRCCCHYNHCACGCCCMC
GKGGGCGTGDNRDGGGYGKGKB		 SELEX
Yin et al.(2017)
KLF11_eDBD_Methyl-HT-SELEX 		0.804 0.928
KLF10
M04489_2.00 		Homo sapiens
RMCACRCCCMYVHCACRCCCMC
GKGGGYGTGDBRKGGGYGTGKY		 SELEX
Yin et al.(2017)
KLF10_eDBD_HT-SELEX 		0.784 0.826
KLF10
M08246_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 ChIP-seq
Najafabadi et al.(2015b)
KLF10 		0.784 0.826
KLF10
M08317_2.00 		Homo sapiens
SMCMCRCCCMYNBSN
NSVNRKGGGYGKGKS		 ChIP-seq
Schmitges et al.(2016)
Q13118.MEME 		0.784 0.826
KLF10
M10228_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TIEG1_Q6 		0.784 0.826
KLF10
M04490_2.00 		Homo sapiens
RMCACRCCCMYGMCACRCCCHC
GDGGGYGTGKCRKGGGYGTGKY		 SELEX
Yin et al.(2017)
KLF10_eDBD_Methyl-HT-SELEX 		0.784 0.826
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000112617 C2H2 ZF 359 383
ENSDARP00000112617 C2H2 ZF 389 413
ENSDARP00000112617 C2H2 ZF 419 441

Links

Other C2H2 ZF family TFs
Other Danio rerio TFs

Invalid Input OrderBy

157 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action