TF Information

znf281b *(Danio rerio)* C2H2 ZF
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00096 (zf-C2H2)	IPR007087	ENSDARG00000035910	T090889_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in hindbrain; midbrain; neural plate; and neural tube. Orthologous to human ZNF281 (zinc finger protein 281). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Zfp281 M00139_2.00	Mus musculus	NHDCCCCCHH	DDGGGGGHDN	PBM Badis et al.(2009) Zfp281_0973	0.801	0.901
ZNF281 M04509_2.00	Homo sapiens	SCCCCTCCCCCM	KGGGGGAGGGGS	SELEX Yin et al.(2017) ZNF281_eDBD_HT-SELEX	0.801	0.901
ZNF281 M08321_2.00	Homo sapiens	BNCCCCTCCCCC	GGGGGAGGGGNV	ChIP-seq Schmitges et al.(2016) Q9Y2X9_1-4.RCADE	0.801	0.901
Zfp281 M08025_2.00	Mus musculus	CCCCWCCCCCMVCHB	VDGBKGGGGGWGGGG	ChIP-seq Chen et al.(2011) GSE11329_zfp281	0.801	0.901
ZNF281 M08906_2.00	Homo sapiens	BCCCCTCCCCCHNYN	NRNDGGGGGAGGGGV	Misc Kulakovskiy et al.(2013) ZN281_HUMAN.H11MO.0.A	0.801	0.901
Zfp281 M08999_2.00	Mus musculus	CCCCTCCCCCMMCBB	VVGKKGGGGGAGGGG	Misc Kulakovskiy et al.(2013) ZN281_MOUSE.H11MO.0.A	0.801	0.901
ZNF281 M10237_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ZFP281_01	0.801	0.901
ZNF281 M04510_2.00	Homo sapiens	RCCCMTCCCCCR	YGGGGGAKGGGY	SELEX Yin et al.(2017) ZNF281_eDBD_Methyl-HT-SELEX	0.801	0.901
For this family, TFs with SR scores > 0.755* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSDARP00000120960	C2H2 ZF	181	203	HICEHCSAAFRSSYHLRRHVLIH
ENSDARP00000120960	C2H2 ZF	209	231	FRCSQCNMSFIQKYLLQRHEKIH
ENSDARP00000120960	C2H2 ZF	237	259	FSCDQCNMRFIQKYHMERHKRTH
ENSDARP00000120960	C2H2 ZF	265	286	YKCDTCLQYFSRTDRLLKHKRT

Links
Other C2H2 ZF family TFs
Other *Danio rerio* TFs

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60 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action