ZIC2 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000043355 T094786_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZIC2
M08233_2.00
Homo sapiens
BBCCTGCWGNB

VNCWGCAGGVV
ChIP-seq
Najafabadi et al.(2015b)
ZIC2
(Direct) (Direct)
ZIC2
M10107_2.00
Homo sapiens
VACCMCCCH

DGGGKGGTB
Transfac
Matys et al.(2006)
V$ZIC2_01
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Zic2
M00150_2.00
Mus musculus
NCMYVYNRNN

NNYNRBRKGN
PBM
Badis et al.(2009)
Zic2_2895
0.827 1.000
Zic2
M09011_2.00
Mus musculus
NRMYHCCTGCTGDGH

DCHCAGCAGGDRKYN
Misc
Kulakovskiy et al.(2013)
ZIC2_MOUSE.H11MO.0.C
0.827 1.000
Zic1
M00137_2.00
Mus musculus
NCMYVBNGNK

MNCNVBRKGN
PBM
Badis et al.(2009)
Zic1_0991
0.804 0.973
ZIC1
M02893_2.00
Homo sapiens
KRCCCCCYGCTGYG

CRCAGCRGGGGGYM
SELEX
Jolma et al.(2013)
ZIC1_1
0.804 0.973
ZIC1
M04485_2.00
Homo sapiens
BVCCMCCYGYHGYGH

DCRCDRCRGGKGGBV
SELEX
Yin et al.(2017)
ZIC1_eDBD_HT-SELEX
0.804 0.973
ZIC1
M04487_2.00
Homo sapiens
BVCCCCCYGCTGYGH

DCRCAGCRGGGGGBV
SELEX
Yin et al.(2017)
ZIC1_FL_HT-SELEX
0.804 0.973
ZIC1
M08900_2.00
Homo sapiens
BMSCHCCCM

KGGGDGSKV
Misc
Kulakovskiy et al.(2013)
ZIC1_HUMAN.H11MO.0.B
0.804 0.973
Zic1
M08990_2.00
Mus musculus
BMSCHCCCM

KGGGDGSKV
Misc
Kulakovskiy et al.(2013)
ZIC1_MOUSE.H11MO.0.B
0.804 0.973
ZIC1
M10226_2.00
Homo sapiens
KRCNMMCYV

BRGKKNGTM
Transfac
Matys et al.(2006)
V$ZIC1_01
0.804 0.973
ZIC1
M10227_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$ZIC1_Q2
0.804 0.973
ZIC1
M04486_2.00
Homo sapiens
BACCCCCYRCTGTGM

KCACAGYRGGGGGTV
SELEX
Yin et al.(2017)
ZIC1_eDBD_Methyl-HT-SELEX
0.804 0.973
ZIC1
M04488_2.00
Homo sapiens
BRCCCCCTGCTGTGH

DCACAGCAGGGGGYV
SELEX
Yin et al.(2017)
ZIC1_FL_Methyl-HT-SELEX
0.804 0.973
Zic3
M00151_2.00
Mus musculus
NCMYVBNRNB

VNYNVBRKGN
PBM
Badis et al.(2009)
Zic3_3119
0.795 0.911
ZIC3
M02894_2.00
Homo sapiens
BACCCCCYGCKGYGH

DCRCMGCRGGGGGTV
SELEX
Jolma et al.(2013)
ZIC3_1
0.795 0.911
Zic3
M02936_2.00
Mus musculus
KRCCCCCYGCTGYGH

DCRCAGCRGGGGGYM
SELEX
Jolma et al.(2013)
Zic3_1
0.795 0.911
ZIC3
M04491_2.00
Homo sapiens
VGACCCCCYGCTGTGM

KCACAGCRGGGGGTCB
SELEX
Yin et al.(2017)
ZIC3_eDBD_HT-SELEX
0.795 0.911
ZIC3
M04493_2.00
Homo sapiens
BACCCCCYGCTGYGH

DCRCAGCRGGGGGTV
SELEX
Yin et al.(2017)
ZIC3_FL_HT-SELEX
0.795 0.911
ZIC3
M08902_2.00
Homo sapiens
NVVYHCCTGCTGDGN

NCHCAGCAGGDRBBN
Misc
Kulakovskiy et al.(2013)
ZIC3_HUMAN.H11MO.0.B
0.795 0.911
Zic3
M09013_2.00
Mus musculus
NVVYHCCTGCTGDGN

NCHCAGCAGGDRBBN
Misc
Kulakovskiy et al.(2013)
ZIC3_MOUSE.H11MO.0.A
0.795 0.911
ZIC3
M10229_2.00
Homo sapiens
VRBCMCCCN

NGGGKGVYB
Transfac
Matys et al.(2006)
V$ZIC3_01
0.795 0.911
Zic3
M10359_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$ZIC3_07
0.795 0.911
ZIC3
M04492_2.00
Homo sapiens
NKACCCCCTGCTGTGM

KCACAGCAGGGGGTMN
SELEX
Yin et al.(2017)
ZIC3_eDBD_Methyl-HT-SELEX
0.795 0.911
ZIC3
M04494_2.00
Homo sapiens
BRCCCCCTGCTGTGM

KCACAGCAGGGGGYV
SELEX
Yin et al.(2017)
ZIC3_FL_Methyl-HT-SELEX
0.795 0.911
ZIC4
M02912_2.00
Homo sapiens
KRCCCCCYGYDGNGH

DCNCHRCRGGGGGYM
SELEX
Jolma et al.(2013)
ZIC4_1
0.788 0.902
ZIC4
M04566_2.00
Homo sapiens
BVCMHCMYRYNRYGH

DCRYNRYRKGDKGBV
SELEX
Yin et al.(2017)
ZIC4_eDBD_HT-SELEX
0.788 0.902
ZIC4
M04567_2.00
Homo sapiens
BRCCHCCYRYBGTKH

DMACVRYRGGDGGYV
SELEX
Yin et al.(2017)
ZIC4_eDBD_Methyl-HT-SELEX
0.788 0.902
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000365514 C2H2 ZF 271 291
ENSP00000365514 C2H2 ZF 300 327
ENSP00000365514 C2H2 ZF 333 357
ENSP00000365514 C2H2 ZF 363 387
ENSP00000365514 C2H2 ZF 393 415
ENSP00000481510 C2H2 ZF 270 290
ENSP00000481510 C2H2 ZF 299 326
ENSP00000481510 C2H2 ZF 332 356
ENSP00000481510 C2H2 ZF 362 386
ENSP00000481510 C2H2 ZF 392 414

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

237 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ZIC4 Homo sapiens ENSG00000174963 D 0.788
Zic2 Mus musculus ENSMUSG00000061524 D 0.827
Zic3 Mus musculus ENSMUSG00000067860 D 0.795
ZIC3 Homo sapiens ENSG00000156925 D 0.795
Zic1 Mus musculus ENSMUSG00000032368 D 0.804
ZIC1 Homo sapiens ENSG00000152977 D 0.804
ZIC2 Sus scrofa ENSSSCG00000009520 I 0.827
ENSSHAG00000015091 Sarcophilus harrisii ENSSHAG00000015091 I 0.792
ENSSHAG00000003850 Sarcophilus harrisii ENSSHAG00000003850 I 0.814
ZIC3 Sorex araneus ENSSARG00000012492 I 0.782
ZIC4 Pan troglodytes ENSPTRG00000015500 I 0.788
ZIC1 Pan troglodytes ENSPTRG00000015501 I 0.804
Zic2 Rattus norvegicus ENSRNOG00000054879 I 0.827
Zic4 Rattus norvegicus ENSRNOG00000014871 I 0.788
Zic3 Rattus norvegicus ENSRNOG00000000861 I 0.795
ZIC3 Pteropus vampyrus ENSPVAG00000011652 I 0.795
ZIC4 Pteropus vampyrus ENSPVAG00000003870 I 0.788
Zic1 Rattus norvegicus ENSRNOG00000014644 I 0.804
ZIC1 Sus scrofa ENSSSCG00000011692 I 0.804
zic2b Tetraodon nigroviridis ENSTNIG00000014979 I 0.816
zic4 Tetraodon nigroviridis ENSTNIG00000012759 I 0.782
zic1 Tetraodon nigroviridis ENSTNIG00000012758 I 0.802
ZIC1 Taeniopygia guttata ENSTGUG00000008838 I 0.804
ENSTGUG00000008837 Taeniopygia guttata ENSTGUG00000008837 I 0.786
ZIC3 Taeniopygia guttata ENSTGUG00000002155 I 0.786
ENSSTOG00000024153 Ictidomys tridecemlineatus ENSSTOG00000024153 I 0.795
ENSSTOG00000023178 Ictidomys tridecemlineatus ENSSTOG00000023178 I 0.827
ENSSTOG00000015977 Ictidomys tridecemlineatus ENSSTOG00000015977 I 0.788
ENSSTOG00000000952 Ictidomys tridecemlineatus ENSSTOG00000000952 I 0.804
ZIC3 Sus scrofa ENSSSCG00000012705 I 0.795
ZIC4 Sus scrofa ENSSSCG00000011693 I 0.788
ZIC2 Pan troglodytes ENSPTRG00000006000 I 0.827
ENSPSIG00000011896 Pelodiscus sinensis ENSPSIG00000011896 I 0.786
ENSPSIG00000009089 Pelodiscus sinensis ENSPSIG00000009089 I 0.756
ENSPANG00000005804 Papio anubis ENSPANG00000005804 I 0.804
zic5 Oryzias latipes ENSORLG00000011124 I 0.756
zic2b Oryzias latipes ENSORLG00000011117 I 0.820
zic4 Oryzias latipes ENSORLG00000010055 I 0.782
zic1 Oryzias latipes ENSORLG00000010050 I 0.809
zic3 Oryzias latipes ENSORLG00000001654 I 0.797
ENSONIG00000006788 Oreochromis niloticus ENSONIG00000006788 I 0.820
ENSONIG00000006787 Oreochromis niloticus ENSONIG00000006787 I 0.756
ENSONIG00000005878 Oreochromis niloticus ENSONIG00000005878 I 0.782
ENSONIG00000005875 Oreochromis niloticus ENSONIG00000005875 I 0.811
ENSONIG00000002716 Oreochromis niloticus ENSONIG00000002716 I 0.797
ZIC2 Otolemur garnettii ENSOGAG00000025901 I 0.827
ENSPANG00000007601 Papio anubis ENSPANG00000007601 I 0.827
ENSPANG00000011357 Papio anubis ENSPANG00000011357 I 0.795
ENSPSIG00000009132 Pelodiscus sinensis ENSPSIG00000009132 I 0.816
ENSPSIG00000005002 Pelodiscus sinensis ENSPSIG00000005002 I 0.804
ENSPSIG00000004881 Pelodiscus sinensis ENSPSIG00000004881 I 0.788
ENSPPYG00000020775 Pongo abelii ENSPPYG00000020775 I 0.795
ENSPPYG00000014188 Pongo abelii ENSPPYG00000014188 I 0.788
ENSPPYG00000005472 Pongo abelii ENSPPYG00000005472 I 0.827
ENSPFOG00000014007 Poecilia formosa ENSPFOG00000014007 I 0.782
ENSPFOG00000013981 Poecilia formosa ENSPFOG00000013981 I 0.811
ENSPFOG00000012982 Poecilia formosa ENSPFOG00000012982 I 0.797
ENSPFOG00000012173 Poecilia formosa ENSPFOG00000012173 I 0.811
ENSPFOG00000012158 Poecilia formosa ENSPFOG00000012158 I 0.756
ZIC4 Procavia capensis ENSPCAG00000008210 I 0.776
ENSPANG00000024745 Papio anubis ENSPANG00000024745 I 0.788
ZIC3 Otolemur garnettii ENSOGAG00000011700 I 0.795
XP_002937379 Xenopus tropicalis XP_002937379 I 0.804
Ogr15027 Ophisaurus gracilis Ogr15027 I 0.790
Ogr05309 Ophisaurus gracilis Ogr05309 I 0.781
Myotis_brandtii_Zic4_10009542 Myotis brandtii Myotis_brandtii_Zic4_10009542 I 0.788
Myotis_brandtii_ZIC3_10005513 Myotis brandtii Myotis_brandtii_ZIC3_10005513 I 0.795
Myotis_brandtii_ZIC1_10009541 Myotis brandtii Myotis_brandtii_ZIC1_10009541 I 0.804
Myotis_brandtii_PCCA_10007322 Myotis brandtii Myotis_brandtii_PCCA_10007322 I 0.823
Gfo_R015355 Geospiza fortis Gfo_R015355 I 0.825
Gfo_R005436 Geospiza fortis Gfo_R005436 I 0.804
ENSP00000397695 Macaca fascicularis ENSP00000397695 I 0.788
ENSP00000397695-D1 Bos grunniens ENSP00000397695-D1 I 0.788
ENSP00000287538 Macaca fascicularis ENSP00000287538 I 0.795
ENSP00000287538-D1 Bos grunniens ENSP00000287538-D1 I 0.795
Ogr15030 Ophisaurus gracilis Ogr15030 I 0.800
Ogr17255 Ophisaurus gracilis Ogr17255 I 0.818
Pvit_01478 Pogona vitticeps Pvit_01478 I 0.790
zic5.S Xenopus laevis XB-GENE-865408 I 0.756
zic3.S Xenopus laevis XB-GENE-865376 I 0.781
zic1.S Xenopus laevis XB-GENE-864815 I 0.794
zic2.S Xenopus laevis XB-GENE-6251643 I 0.818
zic2.L Xenopus laevis XB-GENE-482658 I 0.818
zic5 Xenopus tropicalis XB-GENE-480775 I 0.766
zic3 Xenopus tropicalis XB-GENE-480431 I 0.781
zic4.L Xenopus laevis XB-GENE-1033019 I 0.790
zic4 Xenopus tropicalis XB-GENE-1033015 I 0.788
estExt_gwp.C_400285 Branchiostoma floridae estExt_gwp.C_400285 I 0.785
Pvit_14047 Pogona vitticeps Pvit_14047 I 0.818
Pvit_01479 Pogona vitticeps Pvit_01479 I 0.804
ENSP00000282928 Macaca fascicularis ENSP00000282928 I 0.804
ENSP00000282928-D1 Bos grunniens ENSP00000282928-D1 I 0.804
ENSBTAP00000035289-D2 Bos grunniens ENSBTAP00000035289-D2 I 0.827
ENSXMAG00000010996 Xiphophorus maculatus ENSXMAG00000010996 I 0.756
ENSXMAG00000010995 Xiphophorus maculatus ENSXMAG00000010995 I 0.811
ENSXMAG00000009164 Xiphophorus maculatus ENSXMAG00000009164 I 0.802
ENSXMAG00000009162 Xiphophorus maculatus ENSXMAG00000009162 I 0.782
ZIC1 Tursiops truncatus ENSTTRG00000014350 I 0.804
ZIC4 Tursiops truncatus ENSTTRG00000014343 I 0.788
ZIC2 Tursiops truncatus ENSTTRG00000002568 I 0.827
ENSTSYG00000003356 Tarsius syrichta ENSTSYG00000003356 I 0.795
zic4 Takifugu rubripes ENSTRUG00000017765 I 0.782
zic1 Takifugu rubripes ENSTRUG00000017760 I 0.804
zic3 Takifugu rubripes ENSTRUG00000003550 I 0.785
zic3 Tetraodon nigroviridis ENSTNIG00000016841 I 0.772
L798_08424 Zootermopsis nevadensis L798_08424 I 0.783
LotgiG193238 Lottia gigantea LotgiG193238 I 0.781
PHUM303860 Pediculus humanus PHUM303860 I 0.783
Cmyd_10020767 Chelonia mydas Cmyd_10020767 I 0.804
Cmyd_10016552 Chelonia mydas Cmyd_10016552 I 0.816
Alligator_sinensis_CCG018453.1 Alligator sinensis Alligator_sinensis_CCG018453.1 I 0.821
Alligator_sinensis_CCG012205.1 Alligator sinensis Alligator_sinensis_CCG012205.1 I 0.790
Alligator_sinensis_CCG012204.1 Alligator sinensis Alligator_sinensis_CCG012204.1 I 0.804
Alligator_sinensis_CCG005717.1 Alligator sinensis Alligator_sinensis_CCG005717.1 I 0.782
Aan_R013349 Calypte anna Aan_R013349 I 0.804
Aan_R005804 Calypte anna Aan_R005804 I 0.825
Aan_R004772 Calypte anna Aan_R004772 I 0.786
SPU_030070 Strongylocentrotus purpuratus SPU_030070 I 0.783
SPU_028583 Strongylocentrotus purpuratus SPU_028583 I 0.783
SMAR005380 Strigamia maritima SMAR005380 I 0.785
ENSXMAG00000013404 Xiphophorus maculatus ENSXMAG00000013404 I 0.797
ZIC1 Felis catus ENSFCAG00000007061 I 0.804
ZIC1 Dasypus novemcinctus ENSDNOG00000047101 I 0.804
ZIC2 Dasypus novemcinctus ENSDNOG00000043170 I 0.827
ZIC3 Dasypus novemcinctus ENSDNOG00000006192 I 0.795
ZIC4 Dasypus novemcinctus ENSDNOG00000001881 I 0.788
zic3 Danio rerio ENSDARG00000071497 I 0.794
zic2b Danio rerio ENSDARG00000037178 I 0.788
zic4 Danio rerio ENSDARG00000031307 I 0.784
zic5 Danio rerio ENSDARG00000016022 I 0.762
zic1 Danio rerio ENSDARG00000015567 I 0.804
zic2a Danio rerio ENSDARG00000015554 I 0.818
ENSCSAG00000017494 Chlorocebus sabaeus ENSCSAG00000017494 I 0.827
ENSCSAG00000011409 Chlorocebus sabaeus ENSCSAG00000011409 I 0.804
ENSDORG00000014318 Dipodomys ordii ENSDORG00000014318 I 0.795
ZIC3 Equus caballus ENSECAG00000013318 I 0.795
ZIC4 Felis catus ENSFCAG00000007059 I 0.788
ENSFALG00000007094 Ficedula albicollis ENSFALG00000007094 I 0.804
ENSFALG00000007091 Ficedula albicollis ENSFALG00000007091 I 0.790
ENSFALG00000004344 Ficedula albicollis ENSFALG00000004344 I 0.825
ENSFALG00000003772 Ficedula albicollis ENSFALG00000003772 I 0.786
ZIC3 Echinops telfairi ENSETEG00000018846 I 0.795
ZIC2 Echinops telfairi ENSETEG00000007329 I 0.827
ZIC2 Erinaceus europaeus ENSEEUG00000013747 I 0.827
ZIC4 Erinaceus europaeus ENSEEUG00000000251 I 0.788
ZIC1 Equus caballus ENSECAG00000020355 I 0.799
ZIC4 Equus caballus ENSECAG00000020070 I 0.788
ZIC2 Equus caballus ENSECAG00000018593 I 0.827
ENSCSAG00000011405 Chlorocebus sabaeus ENSCSAG00000011405 I 0.788
ENSCSAG00000007453 Chlorocebus sabaeus ENSCSAG00000007453 I 0.795
ZIC2 Cavia porcellus ENSCPOG00000026926 I 0.827
ENSAPLG00000002960 Anas platyrhynchos ENSAPLG00000002960 I 0.804
ENSAMXG00000012325 Astyanax mexicanus ENSAMXG00000012325 I 0.785
ENSAMXG00000010941 Astyanax mexicanus ENSAMXG00000010941 I 0.794
ENSAMXG00000010931 Astyanax mexicanus ENSAMXG00000010931 I 0.804
ENSAMXG00000002323 Astyanax mexicanus ENSAMXG00000002323 I 0.762
ENSAMXG00000002320 Astyanax mexicanus ENSAMXG00000002320 I 0.815
ENSAMEG00000004503 Ailuropoda melanoleuca ENSAMEG00000004503 I 0.827
ENSAMEG00000002684 Ailuropoda melanoleuca ENSAMEG00000002684 I 0.795
ENSAMEG00000002149 Ailuropoda melanoleuca ENSAMEG00000002149 I 0.804
ENSAMEG00000002144 Ailuropoda melanoleuca ENSAMEG00000002144 I 0.788
ZIC1 Anolis carolinensis ENSACAG00000006947 I 0.804
ENSACAG00000003681 Anolis carolinensis ENSACAG00000003681 I 0.818
ENSAPLG00000003027 Anas platyrhynchos ENSAPLG00000003027 I 0.780
ENSAPLG00000010556 Anas platyrhynchos ENSAPLG00000010556 I 0.786
ZIC4 Cavia porcellus ENSCPOG00000010981 I 0.788
ENSCPOG00000002374 Cavia porcellus ENSCPOG00000002374 I 0.795
ZIC2 Callithrix jacchus ENSCJAG00000020988 I 0.827
ZIC3 Callithrix jacchus ENSCJAG00000013792 I 0.795
ZIC1 Callithrix jacchus ENSCJAG00000001524 I 0.804
ZIC3 Canis familiaris ENSCAFG00000018979 I 0.795
ZIC4 Canis familiaris ENSCAFG00000008194 I 0.788
ZIC2 Canis familiaris ENSCAFG00000005835 I 0.827
ZIC2 Bos taurus ENSBTAG00000025246 I 0.827
ZIC3 Bos taurus ENSBTAG00000021413 I 0.795
ZIC1 Bos taurus ENSBTAG00000014751 I 0.800
ZIC4 Bos taurus ENSBTAG00000014749 I 0.788
CapteG160442 Capitella teleta CapteG160442 I 0.779
ZIC3 Felis catus ENSFCAG00000025684 I 0.795
ZIC1 Otolemur garnettii ENSOGAG00000007465 I 0.804
ENSMPUG00000011375 Mustela putorius furo ENSMPUG00000011375 I 0.827
ENSMPUG00000001786 Mustela putorius furo ENSMPUG00000001786 I 0.795
ENSMODG00000021250 Monodelphis domestica ENSMODG00000021250 I 0.786
ZIC3 Monodelphis domestica ENSMODG00000014029 I 0.786
ZIC2 Monodelphis domestica ENSMODG00000007718 I 0.818
ZIC2 Macaca mulatta ENSMMUG00000014822 I 0.827
ZIC1 Macaca mulatta ENSMMUG00000004742 I 0.804
ZIC4 Macaca mulatta ENSMMUG00000004741 I 0.788
ZIC3 Myotis lucifugus ENSMLUG00000011691 I 0.795
ZIC2 Myotis lucifugus ENSMLUG00000003412 I 0.827
ZIC2 Microcebus murinus ENSMICG00000015310 I 0.827
ZIC1 Microcebus murinus ENSMICG00000014401 I 0.804
ENSMPUG00000011764 Mustela putorius furo ENSMPUG00000011764 I 0.804
ENSMPUG00000011767 Mustela putorius furo ENSMPUG00000011767 I 0.788
ZIC4 Otolemur garnettii ENSOGAG00000007463 I 0.797
ZIC4 Oryctolagus cuniculus ENSOCUG00000010959 I 0.788
ZIC3 Oryctolagus cuniculus ENSOCUG00000009358 I 0.795
ENSOARG00000010774 Ovis aries ENSOARG00000010774 I 0.795
ENSOARG00000005467 Ovis aries ENSOARG00000005467 I 0.786
ENSOARG00000005434 Ovis aries ENSOARG00000005434 I 0.804
ZIC4 Ornithorhynchus anatinus ENSOANG00000007364 I 0.788
ENSNLEG00000007808 Nomascus leucogenys ENSNLEG00000007808 I 0.827
ENSNLEG00000003005 Nomascus leucogenys ENSNLEG00000003005 I 0.795
ENSNLEG00000002407 Nomascus leucogenys ENSNLEG00000002407 I 0.804
ENSNLEG00000002375 Nomascus leucogenys ENSNLEG00000002375 I 0.788
Zic4 Mus musculus ENSMUSG00000036972 I 0.788
ZIC4 Microcebus murinus ENSMICG00000014391 I 0.788
ENSMICG00000010339 Microcebus murinus ENSMICG00000010339 I 0.795
ENSMEUG00000014290 Macropus eugenii ENSMEUG00000014290 I 0.786
ENSGMOG00000001788 Gadus morhua ENSGMOG00000001788 I 0.804
ZIC3 Gorilla gorilla ENSGGOG00000011914 I 0.795
ZIC4 Gorilla gorilla ENSGGOG00000008924 I 0.788
ZIC2 Gorilla gorilla ENSGGOG00000006512 I 0.827
ZIC1 Gorilla gorilla ENSGGOG00000001101 I 0.804
ENSGALG00000006811 Gallus gallus ENSGALG00000006811 I 0.804
ENSGALG00000006810 Gallus gallus ENSGALG00000006810 I 0.786
ENSGALG00000006497 Gallus gallus ENSGALG00000006497 I 0.786
zic3 Gasterosteus aculeatus ENSGACG00000017212 I 0.787
zic4 Gasterosteus aculeatus ENSGACG00000003685 I 0.782
zic1 Gasterosteus aculeatus ENSGACG00000003678 I 0.804
zic2b Gasterosteus aculeatus ENSGACG00000001901 I 0.825
ENSGMOG00000001798 Gadus morhua ENSGMOG00000001798 I 0.782
ENSGMOG00000004438 Gadus morhua ENSGMOG00000004438 I 0.785
ENSMEUG00000009632 Macropus eugenii ENSMEUG00000009632 I 0.788
ENSLOCG00000015155 Lepisosteus oculatus ENSLOCG00000015155 I 0.787
ENSLOCG00000007717 Lepisosteus oculatus ENSLOCG00000007717 I 0.782
ENSLOCG00000007706 Lepisosteus oculatus ENSLOCG00000007706 I 0.804
ENSLOCG00000003087 Lepisosteus oculatus ENSLOCG00000003087 I 0.762
ENSLOCG00000003077 Lepisosteus oculatus ENSLOCG00000003077 I 0.818
ZIC1 Loxodonta africana ENSLAFG00000030632 I 0.804
ZIC2 Loxodonta africana ENSLAFG00000008431 I 0.827
ZIC3 Loxodonta africana ENSLAFG00000007048 I 0.765
ENSLACG00000014597 Latimeria chalumnae ENSLACG00000014597 I 0.785
ENSLACG00000008525 Latimeria chalumnae ENSLACG00000008525 I 0.786
ENSGMOG00000019585 Gadus morhua ENSGMOG00000019585 I 0.823
ENSFCAG00000030117 Felis catus ENSFCAG00000030117 I 0.827