PRDM6 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000061455 T094790_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene is a transcriptional repressor and a member of the PRDM family. Family members contain a PR domain and multiple zinc-finger domains. The encoded protein is involved in regulation of vascular smooth muscle cells (VSMC) contractile proteins. Mutations in this gene result in patent ductus arteriosus 3 (PDA3). [provided by RefSeq, Apr 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
PRDM6
M08277_2.00
Homo sapiens
TTTTYYWBHHTTTYYHYTBYN

NRVARDRRAAADDVWRRAAAA
ChIP-seq
Schmitges et al.(2016)
Q9NQX0.MEME
(Direct) (Direct)
PRDM6
M08855_2.00
Homo sapiens
NNKTTTTCYYBYB

VRVRRGAAAAMNN
Misc
Kulakovskiy et al.(2013)
PRDM6_HUMAN.H11MO.0.C
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000384725 C2H2 ZF 473 494
ENSP00000384725 C2H2 ZF 501 523
ENSP00000384725 C2H2 ZF 529 551
ENSP00000384725 C2H2 ZF 557 578

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

51 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPSIG00000007714 Pelodiscus sinensis ENSPSIG00000007714 I 0.827
PRDM6 Pan troglodytes ENSPTRG00000017180 I 0.827
PRDM6 Pteropus vampyrus ENSPVAG00000006781 I 0.827
Prdm6 Rattus norvegicus ENSRNOG00000030486 I 0.827
ENSPANG00000020936 Papio anubis ENSPANG00000020936 I 0.827
PRDM6 Ochotona princeps ENSOPRG00000004020 I 0.827
ENSNLEG00000012064 Nomascus leucogenys ENSNLEG00000012064 I 0.827
PRDM6 Anolis carolinensis ENSACAG00000003401 I 0.827
ENSOARG00000018873 Ovis aries ENSOARG00000018873 I 0.827
PRDM6 Oryctolagus cuniculus ENSOCUG00000003454 I 0.827
ENSSHAG00000009542 Sarcophilus harrisii ENSSHAG00000009542 I 0.827
PRDM6 Sus scrofa ENSSSCG00000014238 I 0.827
Myotis_brandtii_PRDM6_10015768 Myotis brandtii Myotis_brandtii_PRDM6_10015768 I 0.827
Ogr18847 Ophisaurus gracilis Ogr18847 I 0.827
Pvit_11059 Pogona vitticeps Pvit_11059 I 0.827
prdm6 Xenopus tropicalis XB-GENE-854907 I 0.827
ENSP00000261364 Macaca fascicularis ENSP00000261364 I 0.827
ENSBTAP00000027421-D1 Bos grunniens ENSBTAP00000027421-D1 I 0.827
PRDM6 Tupaia belangeri ENSTBEG00000010088 I 0.827
ENSTSYG00000009407 Tarsius syrichta ENSTSYG00000009407 I 0.827
PRDM6 Tursiops truncatus ENSTTRG00000006808 I 0.827
Alligator_sinensis_CCG004791.1 Alligator sinensis Alligator_sinensis_CCG004791.1 I 0.827
Prdm6 Mus musculus ENSMUSG00000069378 I 0.827
ENSOANG00000001527 Ornithorhynchus anatinus ENSOANG00000001527 I 0.827
ENSCSAG00000014599 Chlorocebus sabaeus ENSCSAG00000014599 I 0.827
ENSCPOG00000004258 Cavia porcellus ENSCPOG00000004258 I 0.827
PRDM6 Dasypus novemcinctus ENSDNOG00000006337 I 0.827
PRDM6 Equus caballus ENSECAG00000004532 I 0.827
PRDM6 Erinaceus europaeus ENSEEUG00000005543 I 0.827
PRDM6 Callithrix jacchus ENSCJAG00000017318 I 0.827
PRDM6 Choloepus hoffmanni ENSCHOG00000003085 I 0.827
ENSAMEG00000015711 Ailuropoda melanoleuca ENSAMEG00000015711 I 0.827
ENSAMXG00000012588 Astyanax mexicanus ENSAMXG00000012588 I 0.827
PRDM6 Bos taurus ENSBTAG00000020578 I 0.827
PRDM6 Canis familiaris ENSCAFG00000023666 I 0.827
ENSMPUG00000012965 Mustela putorius furo ENSMPUG00000012965 I 0.827
ENSFALG00000007522 Ficedula albicollis ENSFALG00000007522 I 0.827
PRDM6 Felis catus ENSFCAG00000026249 I 0.827
ENSMEUG00000011470 Macropus eugenii ENSMEUG00000011470 I 0.827
PRDM6 Myotis lucifugus ENSMLUG00000010064 I 0.827
ENSMICG00000007754 Microcebus murinus ENSMICG00000007754 I 0.827
ENSLOCG00000008663 Lepisosteus oculatus ENSLOCG00000008663 I 0.827
ENSMMUG00000010652 Macaca mulatta ENSMMUG00000010652 I 0.827
PRDM6 Gallus gallus ENSGALG00000005351 I 0.827
PRDM6 Loxodonta africana ENSLAFG00000000396 I 0.827
PRDM6 Monodelphis domestica ENSMODG00000013415 I 0.827
ENSONIG00000013818 Oreochromis niloticus ENSONIG00000013818 I 0.818
ENSPFOG00000000918 Poecilia formosa ENSPFOG00000000918 I 0.818
ENSORLG00000017089 Oryzias latipes ENSORLG00000017089 I 0.818
ENSTNIG00000004450 Tetraodon nigroviridis ENSTNIG00000004450 I 0.762
PRDM6 Takifugu rubripes ENSTRUG00000011582 I 0.762