CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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PRDM6
(
Homo sapiens
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSG00000061455
T094790_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
The protein encoded by this gene is a transcriptional repressor and a member of the PRDM family. Family members contain a PR domain and multiple zinc-finger domains. The encoded protein is involved in regulation of vascular smooth muscle cells (VSMC) contractile proteins. Mutations in this gene result in patent ductus arteriosus 3 (PDA3). [provided by RefSeq, Apr 2017]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
PRDM6
M08277_2.00
Homo sapiens
TTTTYYWBHHTTTYYHYTBYN
NRVARDRRAAADDVWRRAAAA
ChIP-seq
Schmitges et al.(2016)
Q9NQX0.MEME
(Direct)
(Direct)
PRDM6
M08855_2.00
Homo sapiens
NNKTTTTCYYBYB
VRVRRGAAAAMNN
Misc
Kulakovskiy et al.(2013)
PRDM6_HUMAN.H11MO.0.C
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000384725
C2H2 ZF
473
494
WKCGQCFKTFTQRILLQMHVCT
ENSP00000384725
C2H2 ZF
501
523
YQCGHCSQSFSQPSELRNHVVTH
ENSP00000384725
C2H2 ZF
529
551
FKCGYCGRAFAGATTLNNHIRTH
ENSP00000384725
C2H2 ZF
557
578
FKCERCERSFTQATQLSRHQRM
Links
Other
C2H2 ZF
family TFs
Other
Homo sapiens
TFs
51 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy