ZFAT (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000066827 T094795_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000367069 C2H2 ZF 271 293
ENSP00000367069 C2H2 ZF 299 321
ENSP00000367069 C2H2 ZF 326 349
ENSP00000367069 C2H2 ZF 355 377
ENSP00000367069 C2H2 ZF 404 426
ENSP00000367069 C2H2 ZF 458 481
ENSP00000367069 C2H2 ZF 742 764
ENSP00000367069 C2H2 ZF 798 822
ENSP00000367069 C2H2 ZF 830 853
ENSP00000367069 C2H2 ZF 909 931
ENSP00000367069 C2H2 ZF 937 959
ENSP00000367069 C2H2 ZF 966 988
ENSP00000367069 C2H2 ZF 994 1017
ENSP00000367069 C2H2 ZF 1041 1064
ENSP00000394501 C2H2 ZF 259 281
ENSP00000394501 C2H2 ZF 287 309
ENSP00000394501 C2H2 ZF 314 337
ENSP00000394501 C2H2 ZF 343 365
ENSP00000394501 C2H2 ZF 392 414
ENSP00000394501 C2H2 ZF 420 442
ENSP00000394501 C2H2 ZF 446 469
ENSP00000394501 C2H2 ZF 730 752
ENSP00000394501 C2H2 ZF 786 810
ENSP00000394501 C2H2 ZF 818 841
ENSP00000394501 C2H2 ZF 897 919
ENSP00000394501 C2H2 ZF 925 947
ENSP00000394501 C2H2 ZF 954 976
ENSP00000394501 C2H2 ZF 982 1005
ENSP00000394501 C2H2 ZF 1029 1052
ENSP00000427831 C2H2 ZF 259 281
ENSP00000427831 C2H2 ZF 287 309
ENSP00000427831 C2H2 ZF 314 337
ENSP00000427831 C2H2 ZF 343 365
ENSP00000427831 C2H2 ZF 392 414
ENSP00000427831 C2H2 ZF 446 469
ENSP00000427831 C2H2 ZF 730 752
ENSP00000427831 C2H2 ZF 786 810
ENSP00000427831 C2H2 ZF 818 841
ENSP00000427831 C2H2 ZF 897 919
ENSP00000427831 C2H2 ZF 925 947
ENSP00000427831 C2H2 ZF 954 976
ENSP00000427831 C2H2 ZF 982 1005
ENSP00000427831 C2H2 ZF 1029 1052
ENSP00000427879 C2H2 ZF 259 281
ENSP00000427879 C2H2 ZF 287 309
ENSP00000427879 C2H2 ZF 314 337
ENSP00000427879 C2H2 ZF 343 365
ENSP00000427879 C2H2 ZF 392 414
ENSP00000427879 C2H2 ZF 420 442
ENSP00000427879 C2H2 ZF 446 469
ENSP00000427879 C2H2 ZF 730 752
ENSP00000427879 C2H2 ZF 786 810
ENSP00000427879 C2H2 ZF 818 841
ENSP00000427879 C2H2 ZF 897 919
ENSP00000427879 C2H2 ZF 925 947
ENSP00000427879 C2H2 ZF 954 976
ENSP00000427879 C2H2 ZF 982 1005
ENSP00000427879 C2H2 ZF 1029 1052
ENSP00000428483 C2H2 ZF 259 281
ENSP00000428483 C2H2 ZF 287 309
ENSP00000428483 C2H2 ZF 314 337
ENSP00000428483 C2H2 ZF 343 365
ENSP00000428483 C2H2 ZF 392 414
ENSP00000428483 C2H2 ZF 446 469
ENSP00000428483 C2H2 ZF 730 752
ENSP00000428483 C2H2 ZF 786 810
ENSP00000428483 C2H2 ZF 818 841
ENSP00000428483 C2H2 ZF 897 919
ENSP00000428483 C2H2 ZF 925 947
ENSP00000428483 C2H2 ZF 954 976
ENSP00000428483 C2H2 ZF 982 1005
ENSP00000428483 C2H2 ZF 1029 1052
ENSP00000429091 C2H2 ZF 209 231
ENSP00000429091 C2H2 ZF 237 259
ENSP00000429091 C2H2 ZF 264 287
ENSP00000429091 C2H2 ZF 293 315
ENSP00000429091 C2H2 ZF 342 364
ENSP00000429091 C2H2 ZF 396 419
ENSP00000429091 C2H2 ZF 680 702
ENSP00000429091 C2H2 ZF 736 760
ENSP00000429091 C2H2 ZF 768 791
ENSP00000429091 C2H2 ZF 847 869
ENSP00000429091 C2H2 ZF 875 897
ENSP00000429091 C2H2 ZF 904 926
ENSP00000429091 C2H2 ZF 932 955
ENSP00000429091 C2H2 ZF 979 1002
ENSP00000429930 C2H2 ZF 271 293
ENSP00000429930 C2H2 ZF 299 321
ENSP00000429930 C2H2 ZF 326 349
ENSP00000429930 C2H2 ZF 355 377
ENSP00000429930 C2H2 ZF 404 426
ENSP00000429930 C2H2 ZF 458 481
ENSP00000429930 C2H2 ZF 742 764
ENSP00000429930 C2H2 ZF 798 822
ENSP00000429930 C2H2 ZF 830 853
ENSP00000429930 C2H2 ZF 909 931
ENSP00000429930 C2H2 ZF 937 959
ENSP00000429930 C2H2 ZF 966 988
ENSP00000430924 C2H2 ZF 23 46
ENSP00000430924 C2H2 ZF 51 75

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

18 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZFAT Pan troglodytes ENSPTRG00000020607 N 0.818
ZFAT Gorilla gorilla ENSGGOG00000007362 N 0.818
ENSPANG00000017457 Papio anubis ENSPANG00000017457 N 0.817
ENSCSAG00000009828 Chlorocebus sabaeus ENSCSAG00000009828 N 0.817
ENSNLEG00000010576 Nomascus leucogenys ENSNLEG00000010576 N 0.817
ENSSTOG00000006903 Ictidomys tridecemlineatus ENSSTOG00000006903 N 0.816
ZFAT Microcebus murinus ENSMICG00000007692 N 0.816
ZFAT Callithrix jacchus ENSCJAG00000004348 N 0.816
ZFAT Equus caballus ENSECAG00000024767 N 0.816
ZFAT Oryctolagus cuniculus ENSOCUG00000017015 N 0.815
Zfat Rattus norvegicus ENSRNOG00000025140 N 0.814
Zfat Mus musculus ENSMUSG00000022335 N 0.814
ZFAT Cavia porcellus ENSCPOG00000000083 N 0.814
ZFAT Canis familiaris ENSCAFG00000001159 N 0.812
ENSMPUG00000001862 Mustela putorius furo ENSMPUG00000001862 N 0.805
ZFAT Pteropus vampyrus ENSPVAG00000003836 N 0.804
ZFAT Loxodonta africana ENSLAFG00000010205 N 0.792