CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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MZF1
(
Homo sapiens
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSG00000099326
T094821_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
MZF1
M02663_2.00
Homo sapiens
TCCCCN
NGGGGA
SELEX
Mathelier et al.(2014)
MA0056.1
(Direct)
(Direct)
MZF1
M02664_2.00
Homo sapiens
BYHCCCMTMV
BKAKGGGDRV
SELEX
Mathelier et al.(2014)
MA0057.1
(Direct)
(Direct)
MZF1
M08236_2.00
Homo sapiens
CCATTTT
AAAATGG
ChIP-seq
Najafabadi et al.(2015b)
MZF1
(Direct)
(Direct)
MZF1
M08286_2.00
Homo sapiens
HAARATGGCKSCYNN
NNRGSMGCCATYTTD
ChIP-seq
Schmitges et al.(2016)
P28698.MEME
(Direct)
(Direct)
MZF1
M08863_2.00
Homo sapiens
BYNMWTCCCYHYB
VRDRGGGAWKNRV
Misc
Kulakovskiy et al.(2013)
MZF1_HUMAN.H11MO.0.B
(Direct)
(Direct)
MZF1
M10133_2.00
Homo sapiens
TCCCCNHN
NDNGGGGA
Transfac
Matys et al.(2006)
V$MZF1_01
(Direct)
(Direct)
MZF1
M10134_2.00
Homo sapiens
KWBCCCCTMVHHM
KDDBKAGGGGVAM
Transfac
Matys et al.(2006)
V$MZF1_02
(Direct)
(Direct)
MZF1
M10135_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$MZF1_Q5_01
(Direct)
(Direct)
MZF1
M10136_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$MZF1_Q5
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Mzf1
M00773_2.00
Mus musculus
RATCCCCH
DGGGGATY
PBM
Weirauch et al.(2013)
pTH3991
0.801
0.956
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000215057
C2H2 ZF
357
378
RCDVCGKVFSQRSNLLRHQKIH
ENSP00000215057
C2H2 ZF
384
406
FVCSECGRSFSRSSHLLRHQLTH
ENSP00000215057
C2H2 ZF
412
434
FVCGDCGQGFVRSARLEEHRRVH
ENSP00000215057
C2H2 ZF
440
462
FRCAECGQSFRQRSNLLQHQRIH
ENSP00000215057
C2H2 ZF
485
507
FPCSECRESFARRAVLLEHQAVH
ENSP00000215057
C2H2 ZF
513
535
FGCVECGERFGRRSVLLQHRRVH
ENSP00000215057
C2H2 ZF
541
563
FACAECGQSFRQRSNLTQHRRIH
ENSP00000215057
C2H2 ZF
569
591
FACAECGKAFRQRPTLTQHLRVH
ENSP00000215057
C2H2 ZF
597
619
FACPECGQRFSQRLKLTRHQRTH
ENSP00000215057
C2H2 ZF
625
647
YHCGECGLGFTQVSRLTEHQRIH
ENSP00000215057
C2H2 ZF
653
675
FACPECGQSFRQHANLTQHRRIH
ENSP00000215057
C2H2 ZF
681
703
YACPECGKAFRQRPTLTQHLRTH
ENSP00000215057
C2H2 ZF
709
731
FACQDCGRRFHQSTKLIQHQRVH
ENSP00000469493
C2H2 ZF
357
378
RCDVCGKVFSQRSNLLRHQKIH
ENSP00000469493
C2H2 ZF
384
406
FVCSECGRSFSRSSHLLRHQLTH
ENSP00000469493
C2H2 ZF
412
434
FVCGDCGQGFVRSARLEEHRRVH
ENSP00000469493
C2H2 ZF
440
462
FRCAECGQSFRQRSNLLQHQRIH
ENSP00000469493
C2H2 ZF
485
507
FPCSECRESFARRAVLLEHQAVH
ENSP00000469493
C2H2 ZF
513
535
FGCVECGERFGRRSVLLQHRRVH
ENSP00000469493
C2H2 ZF
541
563
FACAECGQSFRQRSNLTQHRRIH
ENSP00000469493
C2H2 ZF
569
591
FACAECGKAFRQRPTLTQHLRVH
ENSP00000469493
C2H2 ZF
597
619
FACPECGQRFSQRLKLTRHQRTH
ENSP00000469493
C2H2 ZF
625
647
YHCGECGLGFTQVSRLTEHQRIH
ENSP00000469493
C2H2 ZF
653
675
FACPECGQSFRQHANLTQHRRIH
ENSP00000469493
C2H2 ZF
681
703
YACPECGKAFRQRPTLTQHLRTH
ENSP00000469493
C2H2 ZF
709
731
FACQDCGRRFHQSTKLIQHQRVH
Links
Other
C2H2 ZF
family TFs
Other
Homo sapiens
TFs
22 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy