SALL4 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000101115 T094824_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
SALL4
M08866_2.00
Homo sapiens
CMCWCCCHNN

NNDGGGWGKG
Misc
Kulakovskiy et al.(2013)
SALL4_HUMAN.H11MO.0.B
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Sall4
M08979_2.00
Mus musculus
CMCWCCCHNN

NNDGGGWGKG
Misc
Kulakovskiy et al.(2013)
SALL4_MOUSE.H11MO.0.A
0.810 0.949
Sall4
M10341_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$DRRS_05
0.810 0.949
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000217086 C2H2 ZF 382 404
ENSP00000217086 C2H2 ZF 410 432
ENSP00000217086 C2H2 ZF 594 616
ENSP00000217086 C2H2 ZF 626 648
ENSP00000217086 C2H2 ZF 872 892
ENSP00000217086 C2H2 ZF 898 920
ENSP00000360594 C2H2 ZF 95 115
ENSP00000360594 C2H2 ZF 121 143
ENSP00000379319 C2H2 ZF 435 455
ENSP00000379319 C2H2 ZF 461 483

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

36 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSAMEG00000013250 Ailuropoda melanoleuca ENSAMEG00000013250 I 0.790
ENSCAFG00000011738 Canis familiaris ENSCAFG00000011738 I 0.790
ENSCJAG00000000591 Callithrix jacchus ENSCJAG00000000591 I 0.827
ENSCJAG00000021107 Callithrix jacchus ENSCJAG00000021107 N 0.827
ENSCSAG00000015269 Chlorocebus sabaeus ENSCSAG00000015269 I 0.827
ENSMLUG00000007060 Myotis lucifugus ENSMLUG00000007060 I 0.806
ENSMLUG00000008405 Myotis lucifugus ENSMLUG00000008405 I 0.781
ENSMPUG00000017543 Mustela putorius furo ENSMPUG00000017543 I 0.790
ENSNLEG00000007013 Nomascus leucogenys ENSNLEG00000007013 I 0.827
ENSP00000217086 Macaca fascicularis ENSP00000217086 I 0.817
ENSPANG00000021792 Papio anubis ENSPANG00000021792 I 0.827
ENSPPYG00000011138 Pongo abelii ENSPPYG00000011138 I 0.790
ENSSTOG00000025002 Ictidomys tridecemlineatus ENSSTOG00000025002 I 0.825
ENSTGUG00000018244 Taeniopygia guttata ENSTGUG00000018244 N 0.758
ENSTSYG00000007359 Tarsius syrichta ENSTSYG00000007359 I 0.795
HelroG138365 Helobdella robusta HelroG138365 N 0.769
Ogr03507 Ophisaurus gracilis Ogr03507 N 0.758
SALL4 Macaca mulatta ENSMMUG00000003870 I 0.827
SALL4 Bos taurus ENSBTAG00000003101 I 0.780
SALL4 Dasypus novemcinctus ENSDNOG00000040633 I 0.827
SALL4 Tursiops truncatus ENSTTRG00000007753 I 0.827
SALL4 Equus caballus ENSECAG00000018533 N 0.827
SALL4 Erinaceus europaeus ENSEEUG00000003649 I 0.827
SALL4 Felis catus ENSFCAG00000002822 I 0.789
SALL4 Sus scrofa ENSSSCG00000007479 I 0.821
Sall4 Rattus norvegicus ENSRNOG00000050035 I 0.816
SALL4 Pteropus vampyrus ENSPVAG00000002075 I 0.819
SALL4 Pan troglodytes ENSPTRG00000013631 I 0.827
SALL4 Gorilla gorilla ENSGGOG00000001832 I 0.827
SALL4 Ochotona princeps ENSOPRG00000011640 I 0.790
SALL4 Otolemur garnettii ENSOGAG00000013799 I 0.790
SALL4 Oryctolagus cuniculus ENSOCUG00000011797 I 0.778
SALL4 Loxodonta africana ENSLAFG00000004309 I 0.817
SALL4 Microcebus murinus ENSMICG00000000027 I 0.825
Sall4 Mus musculus ENSMUSG00000027547 D 0.810