SALL4 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000101115 T094824_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SALL4
M08866_2.00		 Homo sapiens
CMCWCCCHNN
NNDGGGWGKG		 Misc
Kulakovskiy et al.(2013)
SALL4_HUMAN.H11MO.0.B		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Sall4
M08979_2.00 		Mus musculus
CMCWCCCHNN
NNDGGGWGKG		 Misc
Kulakovskiy et al.(2013)
SALL4_MOUSE.H11MO.0.A 		0.810 0.949
Sall4
M10341_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$DRRS_05 		0.810 0.949
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000217086 C2H2 ZF 382 404
ENSP00000217086 C2H2 ZF 410 432
ENSP00000217086 C2H2 ZF 594 616
ENSP00000217086 C2H2 ZF 626 648
ENSP00000217086 C2H2 ZF 872 892
ENSP00000217086 C2H2 ZF 898 920
ENSP00000360594 C2H2 ZF 95 115
ENSP00000360594 C2H2 ZF 121 143
ENSP00000379319 C2H2 ZF 435 455
ENSP00000379319 C2H2 ZF 461 483

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

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36 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action