ZNF423 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000102935 T094830_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development. Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2012]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF423
M10151_2.00		 Homo sapiens
KCACCCWWGGGTGC
GCACCCWWGGGTGM		 Transfac
Matys et al.(2006)
V$ROAZ_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000262383 C2H2 ZF 138 160
ENSP00000262383 C2H2 ZF 166 188
ENSP00000262383 C2H2 ZF 194 216
ENSP00000262383 C2H2 ZF 222 244
ENSP00000262383 C2H2 ZF 263 286
ENSP00000262383 C2H2 ZF 295 318
ENSP00000262383 C2H2 ZF 480 503
ENSP00000262383 C2H2 ZF 517 540
ENSP00000262383 C2H2 ZF 563 588
ENSP00000262383 C2H2 ZF 632 654
ENSP00000262383 C2H2 ZF 663 684
ENSP00000262383 C2H2 ZF 692 715
ENSP00000262383 C2H2 ZF 720 743
ENSP00000262383 C2H2 ZF 750 773
ENSP00000262383 C2H2 ZF 807 830
ENSP00000262383 C2H2 ZF 886 909
ENSP00000262383 C2H2 ZF 930 952
ENSP00000262383 C2H2 ZF 959 981
ENSP00000262383 C2H2 ZF 1229 1252
ENSP00000262383 C2H2 ZF 1259 1282
ENSP00000442321 C2H2 ZF 21 43
ENSP00000442321 C2H2 ZF 49 71
ENSP00000442321 C2H2 ZF 77 99
ENSP00000442321 C2H2 ZF 105 127
ENSP00000442321 C2H2 ZF 146 169
ENSP00000442321 C2H2 ZF 178 201
ENSP00000442321 C2H2 ZF 363 386
ENSP00000442321 C2H2 ZF 400 423
ENSP00000442321 C2H2 ZF 446 471
ENSP00000442321 C2H2 ZF 515 537
ENSP00000442321 C2H2 ZF 546 567
ENSP00000442321 C2H2 ZF 575 598
ENSP00000442321 C2H2 ZF 603 626
ENSP00000442321 C2H2 ZF 633 656
ENSP00000442321 C2H2 ZF 690 713
ENSP00000442321 C2H2 ZF 769 792
ENSP00000442321 C2H2 ZF 813 835
ENSP00000442321 C2H2 ZF 842 864
ENSP00000442321 C2H2 ZF 1112 1135
ENSP00000442321 C2H2 ZF 1142 1165
ENSP00000455061 C2H2 ZF 21 43
ENSP00000455061 C2H2 ZF 49 71
ENSP00000455061 C2H2 ZF 77 99
ENSP00000455061 C2H2 ZF 105 127
ENSP00000455061 C2H2 ZF 146 169
ENSP00000455061 C2H2 ZF 178 201
ENSP00000455061 C2H2 ZF 363 386
ENSP00000455061 C2H2 ZF 400 423
ENSP00000455061 C2H2 ZF 446 471
ENSP00000455061 C2H2 ZF 515 537
ENSP00000455061 C2H2 ZF 546 567
ENSP00000455061 C2H2 ZF 575 598
ENSP00000455061 C2H2 ZF 603 626
ENSP00000455061 C2H2 ZF 633 656
ENSP00000455061 C2H2 ZF 690 713
ENSP00000455061 C2H2 ZF 769 792
ENSP00000455061 C2H2 ZF 813 835
ENSP00000455061 C2H2 ZF 842 864
ENSP00000455061 C2H2 ZF 1112 1135
ENSP00000455061 C2H2 ZF 1142 1165
ENSP00000455426 C2H2 ZF 138 160
ENSP00000455426 C2H2 ZF 166 188
ENSP00000455426 C2H2 ZF 194 216
ENSP00000455426 C2H2 ZF 222 244
ENSP00000455426 C2H2 ZF 263 286
ENSP00000455426 C2H2 ZF 295 318
ENSP00000455426 C2H2 ZF 480 503
ENSP00000455426 C2H2 ZF 517 540
ENSP00000455426 C2H2 ZF 563 588
ENSP00000455426 C2H2 ZF 632 654
ENSP00000455426 C2H2 ZF 663 684
ENSP00000455426 C2H2 ZF 692 715
ENSP00000455426 C2H2 ZF 720 743
ENSP00000455426 C2H2 ZF 750 773
ENSP00000455426 C2H2 ZF 807 830
ENSP00000455426 C2H2 ZF 886 909
ENSP00000455426 C2H2 ZF 930 952
ENSP00000455426 C2H2 ZF 959 981
ENSP00000455426 C2H2 ZF 1229 1252
ENSP00000455426 C2H2 ZF 1259 1282
ENSP00000455588 C2H2 ZF 78 100
ENSP00000455588 C2H2 ZF 106 128
ENSP00000455588 C2H2 ZF 134 156
ENSP00000455588 C2H2 ZF 162 184
ENSP00000455588 C2H2 ZF 203 226
ENSP00000455588 C2H2 ZF 235 258
ENSP00000455588 C2H2 ZF 420 443
ENSP00000455588 C2H2 ZF 457 480
ENSP00000455588 C2H2 ZF 503 528
ENSP00000455588 C2H2 ZF 572 594
ENSP00000455588 C2H2 ZF 603 624
ENSP00000455588 C2H2 ZF 632 655
ENSP00000455588 C2H2 ZF 660 683
ENSP00000455588 C2H2 ZF 690 713
ENSP00000455588 C2H2 ZF 747 770
ENSP00000455588 C2H2 ZF 826 849
ENSP00000455588 C2H2 ZF 870 892
ENSP00000455588 C2H2 ZF 899 921
ENSP00000455588 C2H2 ZF 1169 1192
ENSP00000455588 C2H2 ZF 1199 1222
ENSP00000457664 C2H2 ZF 78 100
ENSP00000457664 C2H2 ZF 106 128
ENSP00000457664 C2H2 ZF 134 156
ENSP00000457664 C2H2 ZF 162 184
ENSP00000457664 C2H2 ZF 203 226
ENSP00000457664 C2H2 ZF 235 258
ENSP00000457664 C2H2 ZF 420 443
ENSP00000457664 C2H2 ZF 457 480
ENSP00000457664 C2H2 ZF 503 528
ENSP00000457664 C2H2 ZF 572 594
ENSP00000457664 C2H2 ZF 603 624
ENSP00000457664 C2H2 ZF 632 655
ENSP00000457664 C2H2 ZF 660 683
ENSP00000457664 C2H2 ZF 690 713
ENSP00000457664 C2H2 ZF 747 770
ENSP00000457664 C2H2 ZF 826 849
ENSP00000457664 C2H2 ZF 870 892
ENSP00000457664 C2H2 ZF 899 921
ENSP00000457664 C2H2 ZF 1169 1192
ENSP00000457664 C2H2 ZF 1199 1222
ENSP00000457928 C2H2 ZF 78 100
ENSP00000457928 C2H2 ZF 106 128
ENSP00000457928 C2H2 ZF 134 156
ENSP00000457928 C2H2 ZF 162 184
ENSP00000457928 C2H2 ZF 203 226
ENSP00000457928 C2H2 ZF 235 258
ENSP00000457928 C2H2 ZF 420 443
ENSP00000457928 C2H2 ZF 457 480
ENSP00000457928 C2H2 ZF 503 528
ENSP00000457928 C2H2 ZF 572 594
ENSP00000457928 C2H2 ZF 603 624
ENSP00000457928 C2H2 ZF 632 655
ENSP00000457928 C2H2 ZF 660 683
ENSP00000457928 C2H2 ZF 690 713
ENSP00000457928 C2H2 ZF 747 770
ENSP00000457928 C2H2 ZF 826 849
ENSP00000457928 C2H2 ZF 870 892
ENSP00000457928 C2H2 ZF 899 921
ENSP00000457928 C2H2 ZF 1169 1192
ENSP00000457928 C2H2 ZF 1199 1222

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

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13 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action