RREB1 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000124782 T094891_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
RREB1
M02665_2.00		 Homo sapiens
MCMCMAMMCAMCMMCHMMSV
BSKKDGKKGKTGKKTKGKGK		 SELEX
Mathelier et al.(2014)
MA0073.1		 (Direct) (Direct)
RREB1
M10203_2.00		 Homo sapiens
MCCCAAMCMMMCMM
KKGKKKGKTTGGGK		 Transfac
Matys et al.(2006)
V$RREB1_01		 (Direct) (Direct)
RREB1
M10204_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$RREB1_Q5		 (Direct) (Direct)
RREB1
M10205_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$RREB_Q5		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000305560 C2H2 ZF 66 88
ENSP00000305560 C2H2 ZF 97 119
ENSP00000305560 C2H2 ZF 125 147
ENSP00000305560 C2H2 ZF 643 665
ENSP00000305560 C2H2 ZF 671 693
ENSP00000305560 C2H2 ZF 699 722
ENSP00000305560 C2H2 ZF 753 775
ENSP00000305560 C2H2 ZF 790 813
ENSP00000305560 C2H2 ZF 1512 1534
ENSP00000305560 C2H2 ZF 1540 1562
ENSP00000335574 C2H2 ZF 66 88
ENSP00000335574 C2H2 ZF 97 119
ENSP00000335574 C2H2 ZF 125 147
ENSP00000335574 C2H2 ZF 643 665
ENSP00000335574 C2H2 ZF 671 693
ENSP00000335574 C2H2 ZF 699 722
ENSP00000335574 C2H2 ZF 753 775
ENSP00000335574 C2H2 ZF 790 813
ENSP00000335574 C2H2 ZF 1246 1268
ENSP00000335574 C2H2 ZF 1274 1297
ENSP00000335574 C2H2 ZF 1329 1351
ENSP00000369265 C2H2 ZF 66 88
ENSP00000369265 C2H2 ZF 97 119
ENSP00000369265 C2H2 ZF 125 147
ENSP00000369265 C2H2 ZF 643 665
ENSP00000369265 C2H2 ZF 671 693
ENSP00000369265 C2H2 ZF 699 722
ENSP00000369265 C2H2 ZF 753 775
ENSP00000369265 C2H2 ZF 790 813
ENSP00000369265 C2H2 ZF 1512 1534
ENSP00000369265 C2H2 ZF 1540 1562
ENSP00000369270 C2H2 ZF 66 88
ENSP00000369270 C2H2 ZF 97 119
ENSP00000369270 C2H2 ZF 125 147
ENSP00000369270 C2H2 ZF 643 665
ENSP00000369270 C2H2 ZF 671 693
ENSP00000369270 C2H2 ZF 699 722
ENSP00000369270 C2H2 ZF 753 775
ENSP00000369270 C2H2 ZF 790 813
ENSP00000369270 C2H2 ZF 1246 1268
ENSP00000369270 C2H2 ZF 1274 1297
ENSP00000369270 C2H2 ZF 1567 1589
ENSP00000369270 C2H2 ZF 1595 1617
ENSP00000419511 C2H2 ZF 66 88
ENSP00000419511 C2H2 ZF 97 119
ENSP00000419511 C2H2 ZF 125 147
ENSP00000419511 C2H2 ZF 643 665
ENSP00000419511 C2H2 ZF 671 693
ENSP00000419511 C2H2 ZF 699 722
ENSP00000419511 C2H2 ZF 753 775
ENSP00000420299 C2H2 ZF 66 88
ENSP00000420299 C2H2 ZF 97 119
ENSP00000420299 C2H2 ZF 125 147
ENSP00000420519 C2H2 ZF 66 88
ENSP00000420519 C2H2 ZF 97 119
ENSP00000420519 C2H2 ZF 125 136
ENSP00000483108 C2H2 ZF 580 602
ENSP00000483108 C2H2 ZF 608 630

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

44 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action