CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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HIVEP3
(
Homo sapiens
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSG00000127124
T094902_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
This gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family. Members of this protein family contain multiple zinc finger and acid-rich (ZAS) domains and serine-threonine rich regions. This protein acts as a transcription factor and is able to regulate nuclear factor kappaB-mediated transcription by binding the kappaB motif in target genes. This protein also binds the recombination signal sequence that flanks the V, D, and J regions of immunoglobulin and T-cell receptors. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Sep 2011]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
HIVEP2
M10101_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$MIBP1_Q6
0.797
0.924
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000247584
C2H2 ZF
192
214
YICQYCSRPCAKPSVLQKHIRSH
ENSP00000247584
C2H2 ZF
220
242
YPCGPCGFSFKTKSNLYKHRKSH
ENSP00000247584
C2H2 ZF
1754
1776
YVCEECGIRCKKPSMLKKHIRTH
ENSP00000247584
C2H2 ZF
1782
1806
YVCKHCHFAFKTKGNLTKHMKSKAH
ENSP00000361664
C2H2 ZF
192
214
YICQYCSRPCAKPSVLQKHIRSH
ENSP00000361664
C2H2 ZF
220
242
YPCGPCGFSFKTKSNLYKHRKSH
ENSP00000361664
C2H2 ZF
1754
1776
YVCEECGIRCKKPSMLKKHIRTH
ENSP00000361664
C2H2 ZF
1782
1806
YVCKHCHFAFKTKGNLTKHMKSKAH
ENSP00000361665
C2H2 ZF
192
214
YICQYCSRPCAKPSVLQKHIRSH
ENSP00000361665
C2H2 ZF
220
242
YPCGPCGFSFKTKSNLYKHRKSH
ENSP00000361665
C2H2 ZF
1754
1776
YVCEECGIRCKKPSMLKKHIRTH
ENSP00000361665
C2H2 ZF
1782
1806
YVCKHCHFAFKTKGNLTKHMKSKAH
Links
Other
C2H2 ZF
family TFs
Other
Homo sapiens
TFs
199 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy