ZNF304 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000131845 T094924_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein functions as a transcriptional repressor that recruits a corepressor complex to stimulate promoter hypermethylation and transcriptional silencing of target genes. Expression of this gene is upregulated in colorectal, ovarian and breast cancer, and this gene may promote cancer cell survival, growth and invasion. [provided by RefSeq, Jul 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF304
M07587_2.00
Homo sapiens
BNCCBKCCCCRVYCBRSYCBBNNN

NNNVVGRSYVGRBYGGGGMVGGNV
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF304.RCADE.ReprocessedData
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000282286 C2H2 ZF 194 215
ENSP00000282286 C2H2 ZF 251 273
ENSP00000282286 C2H2 ZF 279 301
ENSP00000282286 C2H2 ZF 307 329
ENSP00000282286 C2H2 ZF 335 357
ENSP00000282286 C2H2 ZF 363 385
ENSP00000282286 C2H2 ZF 391 413
ENSP00000282286 C2H2 ZF 419 441
ENSP00000282286 C2H2 ZF 447 469
ENSP00000282286 C2H2 ZF 475 497
ENSP00000282286 C2H2 ZF 503 525
ENSP00000282286 C2H2 ZF 531 553
ENSP00000282286 C2H2 ZF 559 581
ENSP00000282286 C2H2 ZF 587 609
ENSP00000282286 C2H2 ZF 615 637
ENSP00000375586 C2H2 ZF 194 215
ENSP00000375586 C2H2 ZF 251 273
ENSP00000375586 C2H2 ZF 279 301
ENSP00000375586 C2H2 ZF 307 329
ENSP00000375586 C2H2 ZF 335 357
ENSP00000375586 C2H2 ZF 363 385
ENSP00000375586 C2H2 ZF 391 413
ENSP00000375586 C2H2 ZF 419 441
ENSP00000375586 C2H2 ZF 447 469
ENSP00000375586 C2H2 ZF 475 497
ENSP00000375586 C2H2 ZF 503 525
ENSP00000375586 C2H2 ZF 531 553
ENSP00000375586 C2H2 ZF 559 581
ENSP00000375586 C2H2 ZF 587 609
ENSP00000375586 C2H2 ZF 615 637
ENSP00000401642 C2H2 ZF 241 262
ENSP00000401642 C2H2 ZF 298 320
ENSP00000401642 C2H2 ZF 326 348
ENSP00000401642 C2H2 ZF 354 376
ENSP00000401642 C2H2 ZF 382 404
ENSP00000401642 C2H2 ZF 410 432
ENSP00000401642 C2H2 ZF 438 460
ENSP00000401642 C2H2 ZF 466 488
ENSP00000401642 C2H2 ZF 494 516
ENSP00000401642 C2H2 ZF 522 544
ENSP00000401642 C2H2 ZF 550 572
ENSP00000401642 C2H2 ZF 578 600
ENSP00000401642 C2H2 ZF 606 628
ENSP00000401642 C2H2 ZF 634 656
ENSP00000401642 C2H2 ZF 662 684
ENSP00000470319 C2H2 ZF 152 173
ENSP00000470319 C2H2 ZF 209 231
ENSP00000470319 C2H2 ZF 237 259
ENSP00000470319 C2H2 ZF 265 287
ENSP00000470319 C2H2 ZF 293 315
ENSP00000470319 C2H2 ZF 321 343
ENSP00000470319 C2H2 ZF 349 371
ENSP00000470319 C2H2 ZF 377 399
ENSP00000470319 C2H2 ZF 405 427
ENSP00000470319 C2H2 ZF 433 455
ENSP00000470319 C2H2 ZF 461 483
ENSP00000470319 C2H2 ZF 489 511
ENSP00000470319 C2H2 ZF 517 539
ENSP00000470319 C2H2 ZF 545 567
ENSP00000470319 C2H2 ZF 573 595

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

7 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPPYG00000010462 Pongo abelii ENSPPYG00000010462 I 0.821
ENSNLEG00000010939 Nomascus leucogenys ENSNLEG00000010939 I 0.810
ENSMMUP00000025340 Macaca fascicularis ENSMMUP00000025340 I 0.770
ZNF304 Macaca mulatta ENSMMUG00000019284 I 0.770
ENSPANG00000012856 Papio anubis ENSPANG00000012856 I 0.770
ENSCSAG00000001643 Chlorocebus sabaeus ENSCSAG00000001643 I 0.770