RBAK (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000146587 T094959_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
RBAK
M07595_2.00		 Homo sapiens
BSYYBYTYSTYHCBN
NVGDRASRARVRRSV		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
RBAK.RCADE.ReprocessedData		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000275423 C2H2 ZF 261 283
ENSP00000275423 C2H2 ZF 289 311
ENSP00000275423 C2H2 ZF 317 339
ENSP00000275423 C2H2 ZF 345 367
ENSP00000275423 C2H2 ZF 373 395
ENSP00000275423 C2H2 ZF 401 423
ENSP00000275423 C2H2 ZF 429 451
ENSP00000275423 C2H2 ZF 457 479
ENSP00000275423 C2H2 ZF 511 530
ENSP00000275423 C2H2 ZF 539 561
ENSP00000275423 C2H2 ZF 567 589
ENSP00000275423 C2H2 ZF 595 617
ENSP00000275423 C2H2 ZF 623 645
ENSP00000275423 C2H2 ZF 651 673
ENSP00000275423 C2H2 ZF 679 701
ENSP00000380120 C2H2 ZF 261 283
ENSP00000380120 C2H2 ZF 289 311
ENSP00000380120 C2H2 ZF 317 339
ENSP00000380120 C2H2 ZF 345 367
ENSP00000380120 C2H2 ZF 373 395
ENSP00000380120 C2H2 ZF 401 423
ENSP00000380120 C2H2 ZF 429 451
ENSP00000380120 C2H2 ZF 457 479
ENSP00000380120 C2H2 ZF 511 530
ENSP00000380120 C2H2 ZF 539 561
ENSP00000380120 C2H2 ZF 567 589
ENSP00000380120 C2H2 ZF 595 617
ENSP00000380120 C2H2 ZF 623 645
ENSP00000380120 C2H2 ZF 651 673
ENSP00000380120 C2H2 ZF 679 701

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

22 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action