PRDM14 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000147596 T094966_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer. [provided by RefSeq, Dec 2011]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PRDM14
M08897_2.00		 Homo sapiens
NRGGWCYCTAACYH
DRGTTAGRGWCCYN		 Misc
Kulakovskiy et al.(2013)
PRD14_HUMAN.H11MO.0.A		 (Direct) (Direct)
PRDM14
M09509_2.00		 Homo sapiens
RSTTAGRGACCY
RGGTCYCTAASY		 Misc
Heinz et al.(2010)
H1-PRDM14_GSE22767		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000276594 C2H2 ZF 400 421
ENSP00000276594 C2H2 ZF 432 455
ENSP00000276594 C2H2 ZF 461 483
ENSP00000276594 C2H2 ZF 489 511
ENSP00000276594 C2H2 ZF 517 540
ENSP00000276594 C2H2 ZF 546 568

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

19 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action